MLK3 regulates bone development downstream of the faciogenital dysplasia protein FGD1 in mice - Wikidata - awgldk - TriplyDB

MLK3 regulates bone development downstream of the faciogenital dysplasia protein FGD1 in mice

MLK3 regulates bone development downstream of the faciogenital dysplasia protein FGD1 in mice

http://www.wikidata.org/entity/Q35484970

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p38 MAPK Signaling in Osteoblast Differentiation Mixed-lineage kinase 3 deficiency promotes neointima formation through increased activation of the RhoA pathway in vascular smooth muscle cells The E3 ligase CHIP mediates ubiquitination and degradation of mixed-lineage kinase 3 O-GlcNAc modification of the runt-related transcription factor 2 (Runx2) links osteogenesis and nutrient metabolism in bone marrow mesenchymal stem cells.p38α MAPK is required for tooth morphogenesis and enamel secretion Identification of novel mutations in Mexican patients with Aarskog-Scott syndrome.Clinical Aspects associated with Syndromic forms of Orofacial Clefts in a Colombian population.Lysine 63-linked ubiquitination modulates mixed lineage kinase-3 interaction with JIP1 scaffold protein in cytokine-induced pancreatic β cell death MEKK2 mediates an alternative β-catenin pathway that promotes bone formation Signaling Cascades Governing Cdc42-Mediated Chondrogenic Differentiation and Mensenchymal Condensation Schnurri-3 regulates ERK downstream of WNT signaling in osteoblasts.RNA-binding protein SAMD4 regulates skeleton development through translational inhibition of Mig6 expression.SMURF2 regulates bone homeostasis by disrupting SMAD3 interaction with vitamin D receptor in osteoblasts Role and mechanism of action of leucine-rich repeat kinase 1 in bone.Involvement of mixed lineage kinase 3 in cancer.Focus on the p38 MAPK signaling pathway in bone development and maintenance.Melatonin promotes osteoblast differentiation and mineralization of MC3T3-E1 cells under hypoxic conditions through activation of PKD/p38 pathways.MLK3 promotes melanoma proliferation and invasion and is a target of microRNA-125b.p190-B RhoGAP regulates the functional composition of the mesenchymal microenvironment.Reciprocal regulation of PPARγ and RUNX2 activities in marrow mesenchymal stem cells: Fine balance between p38 MAPK and Protein Phosphatase 5.Review of X-linked syndromes with arthrogryposis or early contractures-aid to diagnosis and pathway identification.H3K36 trimethylation mediated by SETD2 regulates the fate of bone marrow mesenchymal stem cells

P2860

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P2860

MLK3 regulates bone development downstream of the faciogenital dysplasia protein FGD1 in mice

http://www.wikidata.org/entity/Q35484970

description

2011 nî lūn-bûn

@nan

2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

MLK3 regulates bone developmen ...... dysplasia protein FGD1 in mice

@ast

MLK3 regulates bone developmen ...... dysplasia protein FGD1 in mice

@en

type

label

MLK3 regulates bone developmen ...... dysplasia protein FGD1 in mice

@ast

MLK3 regulates bone developmen ...... dysplasia protein FGD1 in mice

@en

prefLabel

MLK3 regulates bone developmen ...... dysplasia protein FGD1 in mice

@ast

MLK3 regulates bone developmen ...... dysplasia protein FGD1 in mice

@en

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P1433

Journal of Clinical Investigation

P1476

MLK3 regulates bone developmen ...... dysplasia protein FGD1 in mice

@en

P2093

Bo Zhai

http://www.w3.org/2001/XMLSchema#string

Dallas Jones

http://www.w3.org/2001/XMLSchema#string

Dorothy Zhang Hu

http://www.w3.org/2001/XMLSchema#string

Jae-Hyuck Shim

http://www.w3.org/2001/XMLSchema#string

Matthew B Greenblatt

http://www.w3.org/2001/XMLSchema#string

Roger J Davis

http://www.w3.org/2001/XMLSchema#string

Roland Baron

http://www.w3.org/2001/XMLSchema#string

Shashi Kant

http://www.w3.org/2001/XMLSchema#string

Sutada Lotinun

http://www.w3.org/2001/XMLSchema#string

Weiguo Zou

http://www.w3.org/2001/XMLSchema#string

P2860

The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42

The kinase activation loop is the key to mixed lineage kinase-3 activation via both autophosphorylation and hematopoietic progenitor kinase 1 phosphorylation

MLK3 is required for mitogen activation of B-Raf, ERK and cell proliferation

A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases

The faciogenital dysplasia gene product FGD1 functions as a Cdc42Hs-specific guanine-nucleotide exchange factor

Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization

Myotonic dystrophy kinase-related Cdc42-binding kinase acts as a Cdc42 effector in promoting cytoskeletal reorganization

Isolation and characterization of the faciogenital dysplasia (Aarskog-Scott syndrome) gene: a putative Rho/Rac guanine nucleotide exchange factor

A non-receptor tyrosine kinase that inhibits the GTPase activity of p21cdc42

The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice

P304

4383-4392

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scholarly article

P356

10.1172/JCI59041

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11

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121

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Laurie H Glimcher

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2011-10-03T00:00:00Z

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51686654

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21965325

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3204846

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