The E2A and tal-1 helix-loop-helix proteins associate in vivo and are modulated by Id proteins during interleukin 6-induced myeloid differentiation.
about
Fetal Alz-50 clone 1, a novel zinc finger protein, binds a specific DNA sequence and acts as a transcriptional regulatorNKX3.1 is a direct TAL1 target gene that mediates proliferation of TAL1-expressing human T cell acute lymphoblastic leukemiaThe AD1 and AD2 transactivation domains of E2A are essential for the antiapoptotic activity of the chimeric oncoprotein E2A-HLFId2 specifically alters regulation of the cell cycle by tumor suppressor proteinsHelix-loop-helix proteins LYL1 and E2a form heterodimeric complexes with distinctive DNA-binding properties in hematolymphoid cellsOLIG2 (BHLHB1), a bHLH transcription factor, contributes to leukemogenesis in concert with LMO1Regulation of pT alpha gene expression by a dosage of E2A, HEB, and SCLLymphoid-specific expression of the Id3 gene in hematopoietic cells. Selective antagonism of E2A basic helix-loop-helix protein associated with Id3-induced differentiation of erythroleukemia cellsDisordered T-cell development and T-cell malignancies in SCL LMO1 double-transgenic mice: parallels with E2A-deficient miceTarget-dependent effect of phosphorylation on the DNA binding activity of the TAL1/SCL oncoproteinThe DNA binding activity of TAL-1 is not required to induce leukemia/lymphoma in miceThe TAL1/SCL transcription factor regulates cell cycle progression and proliferation in differentiating murine bone marrow monocyte precursorsId2 intrinsically regulates lymphoid and erythroid development via interaction with different target proteinsThe E47 transcription factor binds to the enhancer sequences of recombinant murine leukemia viruses and influences enhancer functionInhibitor of differentiation 4 (Id4) is a potential tumor suppressor in prostate cancer.An scl gene product lacking the transactivation domain induces bony abnormalities and cooperates with LMO1 to generate T-cell malignancies in transgenic mice.Disruption of pre-TCR expression accelerates lymphomagenesis in E2A-deficient miceRepression of Id2 expression by Gfi-1 is required for B-cell and myeloid developmentGfi-1 regulates the erythroid transcription factor network through Id2 repression in murine hematopoietic progenitor cells.Ectopic expression of E47 or E12 promotes the death of E2A-deficient lymphomasThe t(14;21)(q11.2;q22) chromosomal translocation associated with T-cell acute lymphoblastic leukemia activates the BHLHB1 geneC/EBPalpha determines hematopoietic cell fate in multipotential progenitor cells by inhibiting erythroid differentiation and inducing myeloid differentiationTranscriptional regulatory networks downstream of TAL1/SCL in T-cell acute lymphoblastic leukemia.Human Cytomegalovirus Immediate-Early 1 Protein Rewires Upstream STAT3 to Downstream STAT1 Signaling Switching an IL6-Type to an IFNγ-Like ResponseInduction of early B cell factor (EBF) and multiple B lineage genes by the basic helix-loop-helix transcription factor E12.Diversity, function, and transcriptional regulation of gut innate lymphocytesA splice variant of the ITF-2 transcript encodes a transcription factor that inhibits MyoD activity.Transcription of tal-1, a putative oncogene playing an important role in childhood T-ALL, can be shown in normal peripheral blood cells by a highly sensitive RT-PCR assay.Efficient retroviral transduction of human B-lymphoid and myeloid progenitors: marked inhibition of their growth by the Pax5 transgene.E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas.ID1 and ID2 are retinoic acid responsive genes and induce a G0/G1 accumulation in acute promyelocytic leukemia cells.The hematopoietic transcription factor SCL binds the p44 subunit of TFIIH.Suppression of interleukin-3-induced gene expression by a C-terminal truncated Stat5: role of Stat5 in proliferation.Tal-1 induces T cell acute lymphoblastic leukemia accelerated by casein kinase IIalpha.E-box sequence and context-dependent TAL1/SCL modulation of basic helix-loop-helix protein-mediated transcriptional activation.Role of DNA sequence in the binding specificity of synthetic basic-helix-loop-helix domains.
P2860
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P2860
The E2A and tal-1 helix-loop-helix proteins associate in vivo and are modulated by Id proteins during interleukin 6-induced myeloid differentiation.
description
1994 nî lūn-bûn
@nan
1994 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
The E2A and tal-1 helix-loop-h ...... duced myeloid differentiation.
@ast
The E2A and tal-1 helix-loop-h ...... duced myeloid differentiation.
@en
type
label
The E2A and tal-1 helix-loop-h ...... duced myeloid differentiation.
@ast
The E2A and tal-1 helix-loop-h ...... duced myeloid differentiation.
@en
prefLabel
The E2A and tal-1 helix-loop-h ...... duced myeloid differentiation.
@ast
The E2A and tal-1 helix-loop-h ...... duced myeloid differentiation.
@en
P2860
P356
P1476
The E2A and tal-1 helix-loop-h ...... duced myeloid differentiation.
@en
P2093
P2860
P304
P356
10.1073/PNAS.91.13.5952
P407
P577
1994-06-01T00:00:00Z