Tal-1 induces T cell acute lymphoblastic leukemia accelerated by casein kinase IIalpha.
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Cell cycle-specific function of Ikaros in human leukemiaDifferential genomic targeting of the transcription factor TAL1 in alternate haematopoietic lineagesThe pleckstrin homology domain-containing protein CKIP-1 is involved in regulation of cell morphology and the actin cytoskeleton and interaction with actin capping proteinTAL1 and LIM-only proteins synergistically induce retinaldehyde dehydrogenase 2 expression in T-cell acute lymphoblastic leukemia by acting as cofactors for GATA3Protein kinase CK2 inhibitor 4,5,6,7-tetrabromobenzotriazole (TBB) induces apoptosis and caspase-dependent degradation of haematopoietic lineage cell-specific protein 1 (HS1) in Jurkat cellsCK2 forms a stable complex with TFIIIB and activates RNA polymerase III transcription in human cells.A pentamer transcriptional complex including tal-1 and retinoblastoma protein downmodulates c-kit expression in normal erythroblastsThe multiple personalities of the regulatory subunit of protein kinase CK2: CK2 dependent and CK2 independent roles reveal a secret identity for CK2beta.Structural features underlying selective inhibition of protein kinase CK2 by ATP site-directed tetrabromo-2-benzotriazoleAutocatalytic tyrosine-phosphorylation of protein kinase CK2 alpha and alpha' subunits: implication of Tyr182Assembly of protein kinase CK2: investigation of complex formation between catalytic and regulatory subunits using a zinc-finger-deficient mutant of CK2betaDisordered T-cell development and T-cell malignancies in SCL LMO1 double-transgenic mice: parallels with E2A-deficient miceTyrosine phosphorylation of protein kinase CK2 by Src-related tyrosine kinases correlates with increased catalytic activity.Modeling T-cell acute lymphoblastic leukemia induced by the SCL and LMO1 oncogenes.The oncogenic T cell LIM-protein Lmo2 forms part of a DNA-binding complex specifically in immature T cellsChromatin immunoselection defines a TAL-1 target geneEmergence of protein kinase CK2 as a key target in cancer therapyGenome-wide distribution of Auts2 binding localizes with active neurodevelopmental genes.Cystic fibrosis transmembrane regulator fragments with the Phe508 deletion exert a dual allosteric control over the master kinase CK2.P/CAF-mediated acetylation regulates the function of the basic helix-loop-helix transcription factor TAL1/SCLSCL, LMO1 and Notch1 reprogram thymocytes into self-renewing cellsProtein kinase CK2: structure, regulation and role in cellular decisions of life and death.ck2-dependent phosphorylation of progesterone receptors (PR) on Ser81 regulates PR-B isoform-specific target gene expression in breast cancer cells.Notch1 contributes to mouse T-cell leukemia by directly inducing the expression of c-mycNotch1 inhibition targets the leukemia-initiating cells in a Tal1/Lmo2 mouse model of T-ALL.Protein kinase CK2 in health and disease: CK2: a key player in cancer biologyHierarchical phosphorylation within the ankyrin repeat domain defines a phosphoregulatory loop that regulates Notch transcriptional activityUnbiased functional proteomics strategy for protein kinase inhibitor validation and identification of bona fide protein kinase substrates: application to identification of EEF1D as a substrate for CK2.Cre-loxP-mediated recombination between the SIL and SCL genes leads to a block in T-cell development at the CD4- CD8- to CD4+ CD8+ transition.Functional annotation of HOT regions in the human genome: implications for human disease and cancer.Disregulated expression of the transcription factor ThPOK during T-cell development leads to high incidence of T-cell lymphomas.Activating Notch1 mutations in mouse models of T-ALL.p16INK4A tumor suppressor gene expression and CD3epsilon deficiency but not pre-TCR deficiency inhibit TAL1-linked T-lineage leukemogenesis.Targeting casein kinase II restores Ikaros tumor suppressor activity and demonstrates therapeutic efficacy in high-risk leukemia.Growth inhibition and apoptosis due to restoration of E2A activity in T cell acute lymphoblastic leukemia cells.Transcription factor SCL is required for c-kit expression and c-Kit function in hemopoietic cells.The alpha catalytic subunit of protein kinase CK2 is required for mouse embryonic developmentHigh incidence of T-cell tumors in E2A-null mice and E2A/Id1 double-knockout mice.UTX inhibition as selective epigenetic therapy against TAL1-driven T-cell acute lymphoblastic leukemiaPRDM14 promotes RAG-dependent Notch1 driver mutations in mouse T-ALL.
P2860
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P2860
Tal-1 induces T cell acute lymphoblastic leukemia accelerated by casein kinase IIalpha.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Tal-1 induces T cell acute lymphoblastic leukemia accelerated by casein kinase IIalpha.
@en
type
label
Tal-1 induces T cell acute lymphoblastic leukemia accelerated by casein kinase IIalpha.
@en
prefLabel
Tal-1 induces T cell acute lymphoblastic leukemia accelerated by casein kinase IIalpha.
@en
P2093
P2860
P1433
P1476
Tal-1 induces T cell acute lymphoblastic leukemia accelerated by casein kinase IIalpha
@en
P2093
P2860
P304
P356
10.1002/J.1460-2075.1996.TB00900.X
P407
P577
1996-10-01T00:00:00Z