The human relevance of information on carcinogenic modes of action: overview.
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Identifying an indoor air exposure limit for formaldehyde considering both irritation and cancer hazardsCreating context for the use of DNA adduct data in cancer risk assessment: I. Data organization.Mode of action and human relevance analysis for nuclear receptor-mediated liver toxicity: A case study with phenobarbital as a model constitutive androstane receptor (CAR) activatorThe Key Events Dose-Response Framework: a cross-disciplinary mode-of-action based approach to examining dose-response and thresholds.Methylated arsenicals: the implications of metabolism and carcinogenicity studies in rodents to human risk assessment.Changes in male rat urinary protein profile during puberty: a pilot study.Toxicology and epidemiology: improving the science with a framework for combining toxicological and epidemiological evidence to establish causal inferencealpha 2u-globulin nephropathy and renal tumors in national toxicology program studiesMode of action: developmental thyroid hormone insufficiency--neurological abnormalities resulting from exposure to propylthiouracil.Mode-of-action analysis for induction of rat liver tumors by pyrethrins: relevance to human cancer risk.Species differences in the hepatic effects of inducers of CYP2B and CYP4A subfamily forms: relationship to rodent liver tumour formation.Guidance for the classification of carcinogens under the Globally Harmonised System of Classification and Labelling of Chemicals (GHS).Hypothesis-based weight of evidence: a tool for evaluating and communicating uncertainties and inconsistencies in the large body of evidence in proposing a carcinogenic mode of action--naphthalene as an example.Challenges in the application of quantitative approaches in risk assessment: a case study with di-(2-ethylhexyl)phthalate.Mode of action framework analysis for receptor-mediated toxicity: The peroxisome proliferator-activated receptor alpha (PPARα) as a case study.Mode of action and dose-response framework analysis for receptor-mediated toxicity: The aryl hydrocarbon receptor as a case study.Human relevance framework for rodent liver tumors induced by the insecticide sulfoxaflor.Mode-of-action and human relevance framework analysis for rat Leydig cell tumors associated with sulfoxaflor.The use of mode of action information in risk assessment: quantitative key events/dose-response framework for modeling the dose-response for key events.The Multiple Chemicals and Actions Model of carcinogenesis. A possible new approach to developing prevention strategies for environmental carcinogenesis.The role of hepatocyte nuclear factor 4-alpha in perfluorooctanoic acid- and perfluorooctanesulfonic acid-induced hepatocellular dysfunction.Different pathways of constitutive androstane receptor-mediated liver hypertrophy and hepatocarcinogenesis in mice treated with piperonyl butoxide or decabromodiphenyl ether.Mode of action: moving toward a more relevant and efficient assessment paradigm.Case study: weight of evidence evaluation of the human health relevance of thiamethoxam-related mouse liver tumors.Integration of novel approaches demonstrates simultaneous metabolic inactivation and CAR-mediated hepatocarcinogenesis of a nitrification inhibitor.Mode of action analysis for the synthetic pyrethroid metofluthrin-induced rat liver tumors: evidence for hepatic CYP2B induction and hepatocyte proliferation.The PPARα-dependent rodent liver tumor response is not relevant to humans: addressing misconceptions.Application of the International Life Sciences Institute Key Events Dose-Response Framework to food contaminants.Perfluoroalkyl acids and related chemistries--toxicokinetics and modes of action.Mode of action in relevance of rodent liver tumors to human cancer risk.IPCS framework for analyzing the relevance of a cancer mode of action for humans.
P2860
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P2860
The human relevance of information on carcinogenic modes of action: overview.
description
2003 nî lūn-bûn
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2003年の論文
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2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
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2003年论文
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name
The human relevance of information on carcinogenic modes of action: overview.
@ast
The human relevance of information on carcinogenic modes of action: overview.
@en
type
label
The human relevance of information on carcinogenic modes of action: overview.
@ast
The human relevance of information on carcinogenic modes of action: overview.
@en
prefLabel
The human relevance of information on carcinogenic modes of action: overview.
@ast
The human relevance of information on carcinogenic modes of action: overview.
@en
P2093
P2860
P356
P1476
The human relevance of information on carcinogenic modes of action: overview.
@en
P2093
Dorothy E Patton
James E Klaunig
M E Bette Meek
Penelope A Fenner-Crisp
Samuel M Cohen
P2860
P304
P356
10.1080/713608371
P407
P577
2003-01-01T00:00:00Z