Np95 is implicated in pericentromeric heterochromatin replication and in major satellite silencing
about
ICBP90, a novel methyl K9 H3 binding protein linking protein ubiquitination with heterochromatin formationRecognition of multivalent histone states associated with heterochromatin by UHRF1 proteinPHD finger recognition of unmodified histone H3R2 links UHRF1 to regulation of euchromatic gene expressionNp95 interacts with de novo DNA methyltransferases, Dnmt3a and Dnmt3b, and mediates epigenetic silencing of the viral CMV promoter in embryonic stem cellsUHRF1 plays a role in maintaining DNA methylation in mammalian cellsTargeted DNA methylation by homology-directed repair in mammalian cells. Transcription reshapes methylation on the repaired gene.Modifiers and Readers of DNA Modifications and Their Impact on Genome Structure, Expression, and Stability in DiseaseNIRF/UHRF2 occupies a central position in the cell cycle network and allows coupling with the epigenetic landscapePartners in crime: The role of tandem modules in gene transcriptionUHRF1, a modular multi-domain protein, regulates replication-coupled crosstalk between DNA methylation and histone modificationsStructural Insight into Coordinated Recognition of Trimethylated Histone H3 Lysine 9 (H3K9me3) by the Plant Homeodomain (PHD) and Tandem Tudor Domain (TTD) of UHRF1 (Ubiquitin-like, Containing PHD and RING Finger Domains, 1) ProteinThe PHD Finger of Human UHRF1 Reveals a New Subgroup of Unmethylated Histone H3 Tail ReadersConserved linker regions and their regulation determine multiple chromatin-binding modes of UHRF1MBD4 interacts with and recruits USP7 to heterochromatic fociWDHD1 modulates the post-transcriptional step of the centromeric silencing pathwayIn Vitro Toxicity and Epigenotoxicity of Different Types of Ambient Particulate MatterThree SRA-domain methylcytosine-binding proteins cooperate to maintain global CpG methylation and epigenetic silencing in Arabidopsis.HAC stability in murine cells is influenced by nuclear localization and chromatin organization.Poly(ADP-ribose) polymerase 1 (PARP1) associates with E3 ubiquitin-protein ligase UHRF1 and modulates UHRF1 biological functionsFunctional dissection of the role of UHRF1 in the regulation of retinoblastoma methylome.UHRF1 is a genome caretaker that facilitates the DNA damage response to gamma-irradiationORTH/VIM proteins that regulate DNA methylation are functional ubiquitin E3 ligases.H3K9me3-binding proteins are dispensable for SETDB1/H3K9me3-dependent retroviral silencing.An Allosteric Interaction Links USP7 to Deubiquitination and Chromatin Targeting of UHRF1.Histone demethylase JARID1C inactivation triggers genomic instability in sporadic renal cancer.Hemi-methylated DNA opens a closed conformation of UHRF1 to facilitate its histone recognition.The PHD domain of Np95 (mUHRF1) is involved in large-scale reorganization of pericentromeric heterochromatinMultivalent histone engagement by the linked tandem Tudor and PHD domains of UHRF1 is required for the epigenetic inheritance of DNA methylation.Mammalian DNA methyltransferases: a structural perspective.KDM2A represses transcription of centromeric satellite repeats and maintains the heterochromatic stateThe role of methyl-binding proteins in chromatin organization and epigenome maintenance.Control of genetic stability by a new heterochromatin compaction pathway involving the Tip60 histone acetyltransferase.Maintenance of Epigenetic Information.Heterochromatin and the molecular mechanisms of 'parent-of-origin' effects in animals.DNA damage regulates UHRF1 stability via the SCF(β-TrCP) E3 ligase.The SRA protein UHRF1 promotes epigenetic crosstalks and is involved in prostate cancer progression.UHRF1 coordinates peroxisome proliferator activated receptor gamma (PPARG) epigenetic silencing and mediates colorectal cancer progression.The multi-domain protein Np95 connects DNA methylation and histone modification.UHRF1 binds G9a and participates in p21 transcriptional regulation in mammalian cells.Uhrf1 and Dnmt1 are required for development and maintenance of the zebrafish lens
P2860
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P2860
Np95 is implicated in pericentromeric heterochromatin replication and in major satellite silencing
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Np95 is implicated in pericent ...... d in major satellite silencing
@ast
Np95 is implicated in pericent ...... d in major satellite silencing
@en
type
label
Np95 is implicated in pericent ...... d in major satellite silencing
@ast
Np95 is implicated in pericent ...... d in major satellite silencing
@en
prefLabel
Np95 is implicated in pericent ...... d in major satellite silencing
@ast
Np95 is implicated in pericent ...... d in major satellite silencing
@en
P2093
P2860
P356
P1476
Np95 is implicated in pericent ...... d in major satellite silencing
@en
P2093
Christian Pistore
Daniela Pecoraro
Diego Negri
Ian Marc Bonapace
Lisa Cantarini
P2860
P304
P356
10.1091/MBC.E06-09-0874
P577
2006-12-20T00:00:00Z