Potentiation of the novel topoisomerase I inhibitor indenoisoquinoline LMP-400 by the cell checkpoint and Chk1-Chk2 inhibitor AZD7762.
about
ATR inhibitors VE-821 and VX-970 sensitize cancer cells to topoisomerase i inhibitors by disabling DNA replication initiation and fork elongation responses.Topotecan synergizes with CHEK1 (CHK1) inhibitor to induce apoptosis in ovarian cancer cells.Structural basis for inhibition of the histone chaperone activity of SET/TAF-Iβ by cytochrome c.Suppression of the metastatic spread of breast cancer by DN10764 (AZD7762)-mediated inhibition of AXL signaling.Combined inhibition of Wee1 and Chk1 gives synergistic DNA damage in S-phase due to distinct regulation of CDK activity and CDC45 loading.Cancer-Specific Synthetic Lethality between ATR and CHK1 Kinase Activities.ATR-mediated phosphorylation of FANCI regulates dormant origin firing in response to replication stress.Topoisomerases: Resistance versus Sensitivity, How Far We Can Go?RhoB promotes γH2AX dephosphorylation and DNA double-strand break repair
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P2860
Potentiation of the novel topoisomerase I inhibitor indenoisoquinoline LMP-400 by the cell checkpoint and Chk1-Chk2 inhibitor AZD7762.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Potentiation of the novel topo ...... d Chk1-Chk2 inhibitor AZD7762.
@ast
Potentiation of the novel topo ...... d Chk1-Chk2 inhibitor AZD7762.
@en
type
label
Potentiation of the novel topo ...... d Chk1-Chk2 inhibitor AZD7762.
@ast
Potentiation of the novel topo ...... d Chk1-Chk2 inhibitor AZD7762.
@en
prefLabel
Potentiation of the novel topo ...... d Chk1-Chk2 inhibitor AZD7762.
@ast
Potentiation of the novel topo ...... d Chk1-Chk2 inhibitor AZD7762.
@en
P2860
P1433
P1476
Potentiation of the novel topo ...... d Chk1-Chk2 inhibitor AZD7762.
@en
P2093
Sheena M Aris
P2860
P304
P356
10.1158/0008-5472.CAN-11-2579
P407
P50
P577
2011-12-21T00:00:00Z