Two atomic constraints unambiguously position the S4 segment relative to S1 and S2 segments in the closed state of Shaker K channel.
about
Strong cooperativity between subunits in voltage-gated proton channelsWater wires in atomistic models of the Hv1 proton channelPortability of paddle motif function and pharmacology in voltage sensorsVoltage-gated proton channels: what's next?Omega pore, an alternative ion channel permeation pathway involved in the development of several channelopathiesStructural Refinement of Proteins by Restrained Molecular Dynamics Simulations with Non-interacting Molecular Fragments.Structure of the transmembrane regions of a bacterial cyclic nucleotide-regulated channelA Conformational Intermediate in Glutamate Receptor ActivationConformational changes and slow dynamics through microsecond polarized atomistic molecular simulation of an integral Kv1.2 ion channelVoltage-gated proton channels: molecular biology, physiology, and pathophysiology of the H(V) familyStructure and function of voltage-gated sodium channels at atomic resolution.Proton currents constrain structural models of voltage sensor activation.Gating of Connexin Channels by transjunctional-voltage: Conformations and models of open and closed states.Molecular and biophysical basis of glutamate and trace metal modulation of voltage-gated Ca(v)2.3 calcium channels.The voltage-gated proton channel Hv1 has two pores, each controlled by one voltage sensor.Molecular dynamics simulation of Kv channel voltage sensor helix in a lipid membrane with applied electric fieldA multiscale model linking ion-channel molecular dynamics and electrostatics to the cardiac action potential.From the gating charge response to pore domain movement: initial motions of Kv1.2 dynamics under physiological voltage changes.The sliding-helix voltage sensor: mesoscale views of a robust structure-function relationship.Hydrophobic plug functions as a gate in voltage-gated proton channels.S1 constrains S4 in the voltage sensor domain of Kv7.1 K+ channels.Non-native R1 substitution in the s4 domain uniquely alters Kv4.3 channel gating.Moving gating charges through the gating pore in a Kv channel voltage sensor.Reduced voltage sensitivity in a K+-channel voltage sensor by electric field remodeling.Transfer of ion binding site from ether-a-go-go to Shaker: Mg2+ binds to resting state to modulate channel openingCalculation of the gating charge for the Kv1.2 voltage-activated potassium channelDown-state model of the voltage-sensing domain of a potassium channel.State-dependent electrostatic interactions of S4 arginines with E1 in S2 during Kv7.1 activationMulti-scale electrophysiology modeling: from atom to organStructural mechanism of voltage-dependent gating in an isolated voltage-sensing domainIon channel voltage sensors: structure, function, and pathophysiology.In search of a consensus model of the resting state of a voltage-sensing domainVoltage-gated sodium channels at 60: structure, function and pathophysiology.A shaker K+ channel with a miniature engineered voltage sensor.The free energy barrier for arginine gating charge translation is altered by mutations in the voltage sensor domain.Capturing distinct KCNQ2 channel resting states by metal ion bridges in the voltage-sensor domain.3₁₀-helix conformation facilitates the transition of a voltage sensor S4 segment toward the down state.Intermediate states of the Kv1.2 voltage sensor from atomistic molecular dynamics simulations.Alpha-scorpion toxin impairs a conformational change that leads to fast inactivation of muscle sodium channels.Control of a final gating charge transition by a hydrophobic residue in the S2 segment of a K+ channel voltage sensor.
P2860
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P2860
Two atomic constraints unambiguously position the S4 segment relative to S1 and S2 segments in the closed state of Shaker K channel.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Two atomic constraints unambig ...... sed state of Shaker K channel.
@ast
Two atomic constraints unambig ...... sed state of Shaker K channel.
@en
type
label
Two atomic constraints unambig ...... sed state of Shaker K channel.
@ast
Two atomic constraints unambig ...... sed state of Shaker K channel.
@en
prefLabel
Two atomic constraints unambig ...... sed state of Shaker K channel.
@ast
Two atomic constraints unambig ...... sed state of Shaker K channel.
@en
P2860
P356
P1476
Two atomic constraints unambig ...... sed state of Shaker K channel.
@en
P2093
Benoît Roux
Francisco Bezanilla
P2860
P304
P356
10.1073/PNAS.0702638104
P407
P577
2007-04-30T00:00:00Z