Design and synthesis of selective, high-affinity inhibitors of human cytochrome P450 2J2.
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Selective inhibitors of CYP2J2 related to terfenadine exhibit strong activity against human cancers in vitro and in vivoCytochrome P450 2J2 is highly expressed in hematologic malignant diseases and promotes tumor cell growthInducible CYP2J2 and its product 11,12-EET promotes bacterial phagocytosis: a role for CYP2J2 deficiency in the pathogenesis of Crohn's disease?Cytochrome P450 2J2: distribution, function, regulation, genetic polymorphisms and clinical significance.Identifying a selective substrate and inhibitor pair for the evaluation of CYP2J2 activityUnusual regioselectivity and active site topology of human cytochrome P450 2J2Roles of the epoxygenase CYP2J2 in the endothelium.Selective, competitive and mechanism-based inhibitors of human cytochrome P450 2J2.Heme Modification Contributes to the Mechanism-Based Inactivation of Human Cytochrome P450 2J2 by Two Terminal Acetylenic Compounds.Role of Arginine 117 in Substrate Recognition by Human Cytochrome P450 2J2
P2860
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P2860
Design and synthesis of selective, high-affinity inhibitors of human cytochrome P450 2J2.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Design and synthesis of selective, high-affinity inhibitors of human cytochrome P450 2J2.
@ast
Design and synthesis of selective, high-affinity inhibitors of human cytochrome P450 2J2.
@en
type
label
Design and synthesis of selective, high-affinity inhibitors of human cytochrome P450 2J2.
@ast
Design and synthesis of selective, high-affinity inhibitors of human cytochrome P450 2J2.
@en
prefLabel
Design and synthesis of selective, high-affinity inhibitors of human cytochrome P450 2J2.
@ast
Design and synthesis of selective, high-affinity inhibitors of human cytochrome P450 2J2.
@en
P2093
P2860
P1476
Design and synthesis of selective, high-affinity inhibitors of human cytochrome P450 2J2.
@en
P2093
Anne-Christine Macherey
Daniel Mansuy
Darryl C Zeldin
Didier Buisson
Patrick M Dansette
Pierre Lafite
Sylvie Dijols
P2860
P304
P356
10.1016/J.BMCL.2006.02.004
P407
P577
2006-02-21T00:00:00Z