Autoantibodies against the amino-terminal cadherin-like binding domain of pemphigus vulgaris antigen are pathogenic
about
Pemphigus vulgaris antibody identifies pemphaxin. A novel keratinocyte annexin-like molecule binding acetylcholinePemphigus foliaceus IgG causes dissociation of desmoglein 1-containing junctions without blocking desmoglein 1 transinteractionNovel human alpha9 acetylcholine receptor regulating keratinocyte adhesion is targeted by Pemphigus vulgaris autoimmunityPemphigus vulgaris antigen, a desmoglein type of cadherin, is localized within keratinocyte desmosomesEpitope definition by proteomic similarity analysis: identification of the linear determinant of the anti-Dsg3 MAb 5H10Desmosomes in acquired diseaseDownregulation of E-cadherin and Desmoglein 1 by autocrine hepatocyte growth factor during melanoma developmentPemphigus vulgaris IgG-induced desmoglein-3 endocytosis and desmosomal disassembly are mediated by a clathrin- and dynamin-independent mechanismGenetic and functional characterization of human pemphigus vulgaris monoclonal autoantibodies isolated by phage display.Pemphigus vulgaris IgG cause loss of desmoglein-mediated adhesion and keratinocyte dissociation independent of epidermal growth factor receptorStructural basis for major histocompatibility complex (MHC)-linked susceptibility to autoimmunity: charged residues of a single MHC binding pocket confer selective presentation of self-peptides in pemphigus vulgaris.HLA class II restriction of autoreactive T cell responses in pemphigus vulgaris: review of the literature and potential applications for the development of a specific immunotherapy.Analysis of the T cells that are potentially involved in autoantibody production in pemphigus vulgaris.Adhesion receptors in health and disease.Loss of the desmosomal protein perp enhances the phenotypic effects of pemphigus vulgaris autoantibodies.Use of autoantigen-knockout mice in developing an active autoimmune disease model for pemphigusMerging experimental data and in silico analysis: a systems-level approach to autoimmune disease and cancer.Correlation of peptide specificity and IgG subclass with pathogenic and nonpathogenic autoantibodies in pemphigus vulgaris: a model for autoimmunityDesmosomes: structure and function in normal and diseased epidermis.p38 MAPK activation is downstream of the loss of intercellular adhesion in pemphigus vulgaris.Pemphigus vulgaris autoantibody profiling by proteomic technique.Pemphigus vulgaris: update on etiopathogenesis, oral manifestations, and management.Autoimmune and infectious skin diseases that target desmogleins.p38MAPK inhibition prevents disease in pemphigus vulgaris mice.Current and prospective understanding of clinical classification, pathomechanisms and therapy in pemphigus.Pathogenic relevance of IgG and IgM antibodies against desmoglein 3 in blister formation in pemphigus vulgarisMolecular genetics of the cutaneous basement membrane zone. Perspectives on epidermolysis bullosa and other blistering skin diseases.Therapy of autoimmune bullous diseasesMice expressing a mutant desmosomal cadherin exhibit abnormalities in desmosomes, proliferation, and epidermal differentiation.Targeted disruption of the pemphigus vulgaris antigen (desmoglein 3) gene in mice causes loss of keratinocyte cell adhesion with a phenotype similar to pemphigus vulgaris.Autoantibodies against adhesion molecules and structures in blistering skin diseasesSelective binding of self peptides to disease-associated major histocompatibility complex (MHC) molecules: a mechanism for MHC-linked susceptibility to human autoimmune diseasesA central role for the armadillo protein plakoglobin in the autoimmune disease pemphigus vulgaris.Multiple cadherin extracellular repeats mediate homophilic binding and adhesion.T cell control in autoimmune bullous skin disorders.Super-Resolution Microscopy Reveals Altered Desmosomal Protein Organization in Tissue from Patients with Pemphigus Vulgaris.Desmoglein autoimmunity in the pathogenesis of pemphigus.Significance of autoimmunity to non-desmoglein targets in pemphigus.Pemphigus in the XXI century: new life to an old story.Enrichment of total serum IgG4 in patients with pemphigus
P2860
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P2860
Autoantibodies against the amino-terminal cadherin-like binding domain of pemphigus vulgaris antigen are pathogenic
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年学术文章
@wuu
1992年学术文章
@zh-cn
1992年学术文章
@zh-hans
1992年学术文章
@zh-my
1992年学术文章
@zh-sg
1992年學術文章
@yue
1992年學術文章
@zh
1992年學術文章
@zh-hant
name
Autoantibodies against the ami ...... ulgaris antigen are pathogenic
@ast
Autoantibodies against the ami ...... ulgaris antigen are pathogenic
@en
type
label
Autoantibodies against the ami ...... ulgaris antigen are pathogenic
@ast
Autoantibodies against the ami ...... ulgaris antigen are pathogenic
@en
prefLabel
Autoantibodies against the ami ...... ulgaris antigen are pathogenic
@ast
Autoantibodies against the ami ...... ulgaris antigen are pathogenic
@en
P2093
P2860
P356
P1476
Autoantibodies against the ami ...... ulgaris antigen are pathogenic
@en
P2093
Klaus-Kovtun V
Prussick R
Stanley JR
P2860
P304
P356
10.1172/JCI115968
P407
P577
1992-09-01T00:00:00Z