Inactivation of Btk by insertion of lacZ reveals defects in B cell development only past the pre-B cell stage.
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Mutations in the human lambda5/14.1 gene result in B cell deficiency and agammaglobulinemiaBLNK: molecular scaffolding through 'cis'-mediated organization of signaling proteinsA phosphorylation site in Bruton's tyrosine kinase selectively regulates B cell calcium signaling efficiency by altering phospholipase C-gamma activation.B cell-specific lentiviral gene therapy leads to sustained B-cell functional recovery in a murine model of X-linked agammaglobulinemia.Early B cell defects.Severe B cell deficiency and disrupted splenic architecture in transgenic mice expressing the E41K mutated form of Bruton's tyrosine kinase.Entering the era of targeted therapy for chronic lymphocytic leukemia: impact on the practicing clinician.BAFF receptor signaling aids the differentiation of immature B cells into transitional B cells following tonic BCR signalingSplice-correction strategies for treatment of X-linked agammaglobulinemia.Pre-B cell receptor signaling induces immunoglobulin κ locus accessibility by functional redistribution of enhancer-mediated chromatin interactions.Correction of the X-linked immunodeficiency phenotype by transgenic expression of human Bruton tyrosine kinase under the control of the class II major histocompatibility complex Ea locus control regionComparison of predicted and actual consequences of missense mutations.Severe B cell deficiency in mice lacking the tec kinase family members Tec and Btk.Bruton's tyrosine kinase regulates the activation of gene rearrangements at the lambda light chain locus in precursor B cells in the mouseIndependent and opposing roles for Btk and lyn in B and myeloid signaling pathways.Bruton's tyrosine kinase mediated signaling enhances leukemogenesis in a mouse model for chronic lymphocytic leukemia.Btk dosage determines sensitivity to B cell antigen receptor cross-linkingCTCF regulates cell cycle progression of alphabeta T cells in the thymus.The role of Bruton's tyrosine kinase in autoimmunity and implications for therapy.The DNA-binding factor Ctcf critically controls gene expression in macrophages.The B lymphocyte-specific coactivator BOB.1/OBF.1 is required at multiple stages of B-cell development.Btk expression is controlled by Oct and BOB.1/OBF.1.Btk is required for an efficient response to erythropoietin and for SCF-controlled protection against TRAIL in erythroid progenitors.Bruton's tyrosine kinase: from X-linked agammaglobulinemia toward targeted therapy for B-cell malignancies.Bruton's tyrosine kinase cooperates with the B cell linker protein SLP-65 as a tumor suppressor in Pre-B cells.Btk regulates macrophage polarization in response to lipopolysaccharide.The B cell antigen receptor controls integrin activity through Btk and PLCgamma2.Role of Bruton's tyrosine kinase in B cells and malignancies.Bruton's Tyrosine Kinase, a Component of B Cell Signaling Pathways, Has Multiple Roles in the Pathogenesis of Lupus.Stimulus strength determines the BTK-dependence of the SHIP1-deficient phenotype in IgE/antigen-triggered mast cellsDistinct Roles for Bruton's Tyrosine Kinase in B Cell Immune Synapse Formation
P2860
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P2860
Inactivation of Btk by insertion of lacZ reveals defects in B cell development only past the pre-B cell stage.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Inactivation of Btk by inserti ...... nly past the pre-B cell stage.
@ast
Inactivation of Btk by inserti ...... nly past the pre-B cell stage.
@en
type
label
Inactivation of Btk by inserti ...... nly past the pre-B cell stage.
@ast
Inactivation of Btk by inserti ...... nly past the pre-B cell stage.
@en
prefLabel
Inactivation of Btk by inserti ...... nly past the pre-B cell stage.
@ast
Inactivation of Btk by inserti ...... nly past the pre-B cell stage.
@en
P2093
P2860
P1433
P1476
Inactivation of Btk by inserti ...... nly past the pre-B cell stage.
@en
P2093
P2860
P304
P407
P577
1996-09-01T00:00:00Z