Participation of the S4 voltage sensor in the Mg2+-dependent activation of large conductance (BK) K+ channels.
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Slo3 K+ channels: voltage and pH dependence of macroscopic currentsBK channels: multiple sensors, one activation gateTwo separate interfaces between the voltage sensor and pore are required for the function of voltage-dependent K(+) channelsStructural basis for calcium and magnesium regulation of a large conductance calcium-activated potassium channel with β1 subunitsA BK (Slo1) channel journey from molecule to physiology.Operation of the voltage sensor of a human voltage- and Ca2+-activated K+ channel.Allosteric mechanism of Ca2+ activation and H+-inhibited gating of the MthK K+ channelA charged residue in S4 regulates coupling among the activation gate, voltage, and Ca2+ sensors in BK channels.Single-channel kinetics of BK (Slo1) channels.Mg(2+) binding to open and closed states can activate BK channels provided that the voltage sensors are elevatedOpposite Effects of the S4-S5 Linker and PIP(2) on Voltage-Gated Channel Function: KCNQ1/KCNE1 and Other Channels.Mg2+ mediates interaction between the voltage sensor and cytosolic domain to activate BK channelsRole of charged residues in the S1-S4 voltage sensor of BK channels.Intra- and intersubunit cooperativity in activation of BK channels by Ca2+Mg2+ enhances voltage sensor/gate coupling in BK channels.Cysteine modification alters voltage- and Ca(2+)-dependent gating of large conductance (BK) potassium channels.The NH2 terminus of RCK1 domain regulates Ca2+-dependent BK(Ca) channel gating.Heme regulates allosteric activation of the Slo1 BK channelGating and ionic currents reveal how the BKCa channel's Ca2+ sensitivity is enhanced by its beta1 subunitInteraction between residues in the Mg2+-binding site regulates BK channel activationBK Channels in Cardiovascular Diseases and AgingThe interface between membrane-spanning and cytosolic domains in Ca²+-dependent K+ channels is involved in β subunit modulation of gating.Transduction of voltage and Ca2+ signals by Slo1 BK channels.Molecular mechanisms of BK channel activation.Ethanol modulates BKCa channels by acting as an adjuvant of calciumInteractions of divalent cations with calcium binding sites of BK channels reveal independent motions within the gating ringBK-type calcium-activated potassium channels: coupling of metal ions and voltage sensing.Molecular Determinants of BK Channel Functional Diversity and Functioning.Voltage sensor of ion channels and enzymes.Activation of large-conductance, Ca2+-activated K+ channels by cannabinoids.Deletion of cytosolic gating ring decreases gate and voltage sensor coupling in BK channelsMg2+-dependent regulation of BK channels: importance of electrostatics.Ethanol Effect on BK Channels is Modulated by Magnesium.Threading the biophysics of mammalian Slo1 channels onto structures of an invertebrate Slo1 channel.Mechanism of increased open probability by a mutation of the BK channel.The Maxi-K (BK) Channel Antagonist Penitrem A as a Novel Breast Cancer-Targeted Therapeutic.
P2860
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P2860
Participation of the S4 voltage sensor in the Mg2+-dependent activation of large conductance (BK) K+ channels.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Participation of the S4 voltag ...... conductance (BK) K+ channels.
@ast
Participation of the S4 voltag ...... conductance (BK) K+ channels.
@en
type
label
Participation of the S4 voltag ...... conductance (BK) K+ channels.
@ast
Participation of the S4 voltag ...... conductance (BK) K+ channels.
@en
prefLabel
Participation of the S4 voltag ...... conductance (BK) K+ channels.
@ast
Participation of the S4 voltag ...... conductance (BK) K+ channels.
@en
P2093
P2860
P356
P1476
Participation of the S4 voltag ...... conductance (BK) K+ channels.
@en
P2093
Frank T Horrigan
Fred Sieling
Gayathri Krishnamoorthy
Guangping Zhang
Jianmin Cui
Jingyi Shi
Zhongming Ma
P2860
P304
10488-10493
P356
10.1073/PNAS.1834300100
P407
P577
2003-08-18T00:00:00Z