Moonlighting activity of presenilin in plants is independent of gamma-secretase and evolutionarily conserved. - Wikidata - awgldk - TriplyDB

Moonlighting activity of presenilin in plants is independent of gamma-secretase and evolutionarily conserved.

Moonlighting activity of presenilin in plants is independent of gamma-secretase and evolutionarily conserved.

http://www.wikidata.org/entity/Q35941365

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A protease-independent function for SPPL3 in NFAT activation Asynchronous evolutionary origins of Aβ and BACE1 Subcellular localization of Arabidopsis arogenate dehydratases suggests novel and non-enzymatic roles Dictyostelium possesses highly diverged presenilin/gamma-secretase that regulates growth and cell-fate specification and can accurately process human APP: a system for functional studies of the presenilin/gamma-secretase complex.Notch and presenilin regulate cellular expansion and cytokine secretion but cannot instruct Th1/Th2 fate acquisition Origin and evolution of the Notch signalling pathway: an overview from eukaryotic genomes.Presenilins and the gamma-secretase: still a complex problem.Gamma-secretase subunits associate in intracellular membrane compartments in Arabidopsis thaliana.Mutagenesis mapping of the presenilin 1 calcium leak conductance pore.Presenilins and γ-secretase: structure, function, and role in Alzheimer Disease.Presenilin transgenic mice as models of Alzheimer's disease.Non-Catalytic Roles of Presenilin Throughout Evolution.Sequence analyses of presenilin mutations linked to familial Alzheimer's disease.Presenilin: RIP and beyond.Presenilins: members of the gamma-secretase quartets, but part-time soloists too.An ancestral non-proteolytic role for presenilin proteins in multicellular development of the social amoeba Dictyostelium discoideum.Plant RMR proteins: unique vacuolar sorting receptors that couple ligand sorting with membrane internalization.Modeling human neurodegenerative diseases in transgenic systems.The very many faces of presenilins and the γ-secretase complex.Biological function of Presenilin and its role in AD pathogenesis Regulated intramembrane proteolysis of the TGFβ type I receptor conveys oncogenic signals.Biogenesis of gamma-secretase early in the secretory pathway.Role of Presenilin in Mitochondrial Oxidative Stress and Neurodegeneration in

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P2860

Moonlighting activity of presenilin in plants is independent of gamma-secretase and evolutionarily conserved.

http://www.wikidata.org/entity/Q35941365

description

2007 nî lūn-bûn

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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2007年论文

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2007年论文

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name

Moonlighting activity of prese ...... and evolutionarily conserved.

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Moonlighting activity of prese ...... and evolutionarily conserved.

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type

label

Moonlighting activity of prese ...... and evolutionarily conserved.

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Moonlighting activity of prese ...... and evolutionarily conserved.

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prefLabel

Moonlighting activity of prese ...... and evolutionarily conserved.

@ast

Moonlighting activity of prese ...... and evolutionarily conserved.

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PNAS.0702038104

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Moonlighting activity of prese ...... and evolutionarily conserved.

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P2093

Abha Khandelwal

http://www.w3.org/2001/XMLSchema#string

Catherine M Roe

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Dilip Chandu

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Ralph S Quatrano

http://www.w3.org/2001/XMLSchema#string

Raphael Kopan

http://www.w3.org/2001/XMLSchema#string

P2860

Role of Notch signaling in cell-fate determination of human mammary stem/progenitor cells

Presenilins form ER Ca2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations

Impas 1 possesses endoproteolytic activity against multipass membrane protein substrate cleaving the presenilin 1 holoprotein

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity

CD147 is a regulatory subunit of the gamma-secretase complex in Alzheimer's disease amyloid beta-peptide production

Role that phosphorylation of GSK3 plays in insulin and Wnt signalling defined by knockin analysis

Presenilin and nicastrin regulate each other and determine amyloid beta-peptide production via complex formation

Nicastrin is critical for stability and trafficking but not association of other presenilin/gamma-secretase components.

Presenilin couples the paired phosphorylation of beta-catenin independent of axin: implications for beta-catenin activation in tumorigenesis

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13337-13342

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scholarly article

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10.1073/PNAS.0702038104

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104

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17684101

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1948938

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