Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase. - Wikidata - awgldk - TriplyDB

Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase.

Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase.

http://www.wikidata.org/entity/Q36103541

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NetPath: a public resource of curated signal transduction pathways Akt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 function Akt augments the oncogenic potential of the HBx protein of hepatitis B virus by phosphorylation Functional cooperation of the interleukin-2 receptor beta chain and Jak1 in phosphatidylinositol 3-kinase recruitment and phosphorylation Multiple forms of p55PIK, a regulatory subunit of phosphoinositide 3-kinase, are generated by alternative initiation of translation Akt phosphorylates and regulates the orphan nuclear receptor Nur77 Tcl1 enhances Akt kinase activity and mediates its nuclear translocation Dual phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 has a therapeutic potential and sensitizes cisplatin in nasopharyngeal carcinoma cbl-b inhibits epidermal growth factor receptor signaling STAM2, a new member of the STAM family, binding to the Janus kinases The costimulation-regulated duration of PKB activation controls T cell longevity Mitogenic activation, phosphorylation, and nuclear translocation of protein kinase Bbeta Modulation of the Akt pathway reveals a novel link with PERK/eIF2α, which is relevant during hypoxia PKB/Akt partners with Dab2 in albumin endocytosis Platelet-derived growth factor-BB-mediated activation of Akt suppresses smooth muscle-specific gene expression through inhibition of mitogen-activated protein kinase and redistribution of serum response factor Akt mediates the effect of insulin on epithelial sodium channels by inhibiting Nedd4-2 PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway The role of Asp-462 in regulating Akt activity Regulation of diacylglycerol kinase alpha by phosphoinositide 3-kinase lipid products Tyrosine 1101 of Tie2 is the major site of association of p85 and is required for activation of phosphatidylinositol 3-kinase and Akt 4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway A new tyrosine-phosphorylated 97-kDa adaptor protein mediates interleukin-2-induced association of SHP-2 with p85-phosphatidylinositol 3-kinase in human T lymphocytes.The sphingosine 1-phosphate receptor S1P₂ maintains the homeostasis of germinal center B cells and promotes niche confinement.Peptide and protein library screening defines optimal substrate motifs for AKT/PKB.Suppression of apoptosis induced by growth factor withdrawal by an oncogenic form of c-Cbl.A winged helix forkhead (FOXD2) tunes sensitivity to cAMP in T lymphocytes through regulation of cAMP-dependent protein kinase RIalpha.IGF-I differentially regulates Bcl-xL and Bax and confers myocardial protection in the rat heart.Neuroprotection by sodium ferulate against glutamate-induced apoptosis is mediated by ERK and PI3 kinase pathways.Oscillations of the p53-Akt network: implications on cell survival and death Apoptosis of CD4+ CD25(high) T cells in type 1 diabetes may be partially mediated by IL-2 deprivation.Regulation of protein kinase B.The Croonian Lecture 1998. Identification of a protein kinase cascade of major importance in insulin signal transduction.The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway.Cigarette smoke regulates VEGFR2-mediated survival signaling in rat lungs Distinct IL-2 receptor signaling pattern in CD4+CD25+ regulatory T cells.Regulation of the postnatal development of dopamine neurons of the substantia nigra in vivo by Akt/protein kinase B.Identification of differentially expressed genes in lung tissues of nickel-exposed rats using suppression subtractive hybridization.mcl-1 is an immediate-early gene activated by the granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling pathway and is one component of the GM-CSF viability response.Naive CD4 t cell proliferation is controlled by mammalian target of rapamycin regulation of GRAIL expression Latent membrane protein 2A-mediated effects on the phosphatidylinositol 3-Kinase/Akt pathway.

P2860

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P2860

Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase.

http://www.wikidata.org/entity/Q36103541

description

1997 nî lūn-bûn

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1997年の論文

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1997年論文

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1997年論文

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1997年論文

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1997年論文

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1997年論文

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1997年论文

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1997年论文

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1997年论文

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name

Transduction of interleukin-2 ...... ignals via Akt protein kinase.

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Transduction of interleukin-2 ...... ignals via Akt protein kinase.

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type

label

Transduction of interleukin-2 ...... ignals via Akt protein kinase.

@ast

Transduction of interleukin-2 ...... ignals via Akt protein kinase.

@en

prefLabel

Transduction of interleukin-2 ...... ignals via Akt protein kinase.

@ast

Transduction of interleukin-2 ...... ignals via Akt protein kinase.

@en

P1433

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P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Transduction of interleukin-2 ...... ignals via Akt protein kinase.

@en

P2093

A Bellacosa

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N N Ahmed

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P N Tsichlis

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T O Chan

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P2860

Three distinct IL-2 signaling pathways mediated by bcl-2, c-myc, and lck cooperate in hematopoietic cell proliferation

AH/PH domain-mediated interaction between Akt molecules and its potential role in Akt regulation

Utilization of the beta and gamma chains of the IL-2 receptor by the novel cytokine IL-15

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

Functional activation of Jak1 and Jak3 by selective association with IL-2 receptor subunits

The adapter protein Shc interacts with the interleukin-2 (IL-2) receptor upon IL-2 stimulation

Protein tyrosine kinase Syk is associated with and activated by the IL-2 receptor: possible link with the c-myc induction pathway

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

T-cell lymphoma lines derived from rat thymomas induced by Moloney murine leukemia virus: phenotypic diversity and its implications

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3627-3632

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10.1073/PNAS.94.8.3627

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H. Leighton Grimes

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14109828

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9108028

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20491

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