Peptidyl-transferase inhibitors have antiviral properties by altering programmed -1 ribosomal frameshifting efficiencies: development of model systems
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Characterization of the frameshift signal of Edr, a mammalian example of programmed -1 ribosomal frameshiftingThe frameshift signal of HIV-1 involves a potential intramolecular triplex RNA structureA three-stemmed mRNA pseudoknot in the SARS coronavirus frameshift signalFactors affecting translation at the programmed -1 ribosomal frameshifting site of Cocksfoot mottle virus RNA in vivo.Mechanisms and implications of programmed translational frameshiftingRibosomal frameshifting and transcriptional slippage: From genetic steganography and cryptography to adventitious useTriple Decoding of Hepatitis C Virus RNA by Programmed Translational FrameshiftingGuanidinoneomycin B Recognition of an HIV-1 RNA HelixThe Mof2/Sui1 protein is a general monitor of translational accuracy.Specific effects of ribosome-tethered molecular chaperones on programmed -1 ribosomal frameshifting.Ribosomal protein L5 helps anchor peptidyl-tRNA to the P-site in Saccharomyces cerevisiae.Importance of ribosomal frameshifting for human immunodeficiency virus type 1 particle assembly and replication.tRNAGlu wobble uridine methylation by Trm9 identifies Elongator's key role for zymocin-induced cell death in yeast.Systematic analysis of bicistronic reporter assay dataIdentification of novel antipoxviral agents: mitoxantrone inhibits vaccinia virus replication by blocking virion assembly.Selection of peptides interfering with a ribosomal frameshift in the human immunodeficiency virus type 1Selection and characterization of small molecules that bind the HIV-1 frameshift site RNA.Ski6p is a homolog of RNA-processing enzymes that affects translation of non-poly(A) mRNAs and 60S ribosomal subunit biogenesis.Ribosomal protein L3 mutants alter translational fidelity and promote rapid loss of the yeast killer virus.Structure and function of the stimulatory RNAs involved in programmed eukaryotic-1 ribosomal frameshifting.Decreased peptidyltransferase activity correlates with increased programmed -1 ribosomal frameshifting and viral maintenance defects in the yeast Saccharomyces cerevisiaeThe pokeweed antiviral protein specifically inhibits Ty1-directed +1 ribosomal frameshifting and retrotransposition in Saccharomyces cerevisiae.Structural and functional analysis of 5S rRNA in Saccharomyces cerevisiaeIdentification of functionally important amino acids of ribosomal protein L3 by saturation mutagenesis.A molecular clamp ensures allosteric coordination of peptidyltransfer and ligand binding to the ribosomal A-siteThe Gag domain of the Gag-Pol fusion protein directs incorporation into the L-A double-stranded RNA viral particles in Saccharomyces cerevisiae.The many paths to frameshifting: kinetic modelling and analysis of the effects of different elongation steps on programmed -1 ribosomal frameshiftingThe potential role of ribosomal frameshifting in generating aberrant proteins implicated in neurodegenerative diseases.Identification of putative programmed -1 ribosomal frameshift signals in large DNA databasesThe 9-A solution: how mRNA pseudoknots promote efficient programmed -1 ribosomal frameshifting.A rapid, inexpensive yeast-based dual-fluorescence assay of programmed--1 ribosomal frameshifting for high-throughput screening.rRNA pseudouridylation defects affect ribosomal ligand binding and translational fidelity from yeast to human cells.The SMC Loader Scc2 Promotes ncRNA Biogenesis and Translational Fidelity.Revealing -1 programmed ribosomal frameshifting mechanisms by single-molecule techniques and computational methodsThe upf3 protein is a component of the surveillance complex that monitors both translation and mRNA turnover and affects viral propagation.Spine expansion and stabilization associated with long-term potentiation.A programmed -1 ribosomal frameshift signal can function as a cis-acting mRNA destabilizing element.Yeast telomere maintenance is globally controlled by programmed ribosomal frameshifting and the nonsense-mediated mRNA decay pathwayDelayed rRNA processing results in significant ribosome biogenesis and functional defects.A homogeneous cell-based bicistronic fluorescence assay for high-throughput identification of drugs that perturb viral gene recoding and read-through of nonsense stop codons.
P2860
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P2860
Peptidyl-transferase inhibitors have antiviral properties by altering programmed -1 ribosomal frameshifting efficiencies: development of model systems
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Peptidyl-transferase inhibitor ...... : development of model systems
@ast
Peptidyl-transferase inhibitor ...... : development of model systems
@en
type
label
Peptidyl-transferase inhibitor ...... : development of model systems
@ast
Peptidyl-transferase inhibitor ...... : development of model systems
@en
prefLabel
Peptidyl-transferase inhibitor ...... : development of model systems
@ast
Peptidyl-transferase inhibitor ...... : development of model systems
@en
P2093
P2860
P356
P1476
Peptidyl-transferase inhibitor ...... : development of model systems
@en
P2093
K Czaplinski
M J Ruiz-Echevarria
P2860
P304
P356
10.1073/PNAS.94.13.6606
P407
P577
1997-06-01T00:00:00Z