Efficient transplantation of BCR-ABL-induced chronic myelogenous leukemia-like syndrome in mice. - Wikidata - awgldk - TriplyDB

Efficient transplantation of BCR-ABL-induced chronic myelogenous leukemia-like syndrome in mice.

Efficient transplantation of BCR-ABL-induced chronic myelogenous leukemia-like syndrome in mice.

http://www.wikidata.org/entity/Q36262876

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Bcr-Abl oncoproteins bind directly to activators of the Ras signalling pathway Transcriptional activation of a ras-like gene (kir) by oncogenic tyrosine kinases MicroRNAs mediated regulation of MAPK signaling pathways in chronic myeloid leukemia A BCR-ABL mutant lacking direct binding sites for the GRB2, CBL and CRKL adapter proteins fails to induce leukemia in mice Murine models of acute leukemia: important tools in current pediatric leukemia research.BCR-ABL enhances differentiation of long-term repopulating hematopoietic stem cells Cytogenetics and molecular genetics of childhood leukemia.Biological consequences of the BCR/ABL fusion gene in humans and mice Signaling by ABL oncogenes through cyclin D1.Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo- and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes.Immature B-cell progenitors survive oncogenic stress and efficiently initiate Ph+ B-acute lymphoblastic leukemia Tumorigenic activity of the BCR-ABL oncogenes is mediated by BCL2.Modeling Philadelphia chromosome positive leukemias.Philadelphia-positive B-cell acute lymphoblastic leukemia is initiated in an uncommitted progenitor cell.Expression of p210 and p190 BCR-ABL due to alternative splicing in chronic myelogenous leukaemia.The Ph-positive and Ph-negative myeloproliferative neoplasms: some topical pre-clinical and clinical issues.Dissecting the molecular mechanism of chronic myelogenous leukemia using murine models.BCR/ABL: from molecular mechanisms of leukemia induction to treatment of chronic myelogenous leukemia.The biology of chronic myelogenous leukemia:mouse models and cell adhesion.The molecular mechanism of chronic myelogenous leukemia and its therapeutic implications: studies in a murine model.Cytokine therapeutics: lessons from interferon alpha SHP-2 phosphatase is required for hematopoietic cell transformation by Bcr-Abl.Expression of BCR/ABL and BCL-2 in myeloid progenitors leads to myeloid leukemias.The P190, P210, and P230 forms of the BCR/ABL oncogene induce a similar chronic myeloid leukemia-like syndrome in mice but have different lymphoid leukemogenic activity.An evolutionary perspective on anti-tumor immunity Regulated expression of P210 Bcr-Abl during embryonic stem cell differentiation stimulates multipotential progenitor expansion and myeloid cell fate Tumour induction by activated abl involves tyrosine phosphorylation of the product of the cbl oncogene.Molecular pathology of tumor-initiating cells: lessons from Philadelphia chromosome-positive leukemia.Evolution of therapies for chronic myelogenous leukemia.Maintaining low BCR-ABL signaling output to restrict CML progression and enable persistence Ameliorating effect of Kalpaamruthaa on altered energy metabolism in BCR-ABL(+) cell line induced leukemic mouse model.Autocrine and paracrine effects of an ES-cell derived, BCR/ABL-transformed hematopoietic cell line that induces leukemia in mice.Retroviral vector design for gene therapy of cancer: specific inhibition and tagging of BCR-ABLp190 cells.Rationalizing autotransplant strategies for chronic myeloid leukemia.Sipa1 deficiency unleashes a host-immune mechanism eradicating chronic myelogenous leukemia-initiating cells.p210BCR/ABL-induced alteration of pre-mRNA splicing in primary human CD34+ hematopoietic progenitor cells.Induction of Chronic Myeloid Leukemia in Mice.

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P2860

Efficient transplantation of BCR-ABL-induced chronic myelogenous leukemia-like syndrome in mice.

http://www.wikidata.org/entity/Q36262876

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1993 nî lūn-bûn

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Efficient transplantation of B ...... eukemia-like syndrome in mice.

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Efficient transplantation of B ...... eukemia-like syndrome in mice.

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Efficient transplantation of B ...... eukemia-like syndrome in mice.

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Efficient transplantation of B ...... eukemia-like syndrome in mice.

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Efficient transplantation of B ...... eukemia-like syndrome in mice.

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Efficient transplantation of B ...... eukemia-like syndrome in mice.

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Efficient transplantation of B ...... eukemia-like syndrome in mice.

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P2093

Gishizky ML

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Johnson-White J

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Witte ON

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P2860

Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22

Letter: A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining

Evidence for regulation of the human ABL tyrosine kinase by a cellular inhibitor

Transformation of an interleukin 3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210bcr/abl protein.

Induction of a chronic myelogenous leukemia-like syndrome in mice with v-abl and BCR/ABL.

Resting and activated subsets of mouse multipotent hematopoietic stem cells.

bcr-abl, the hallmark of chronic myeloid leukaemia in man, induces multiple haemopoietic neoplasms in mice.

An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity.

In vitro transformation of immature hematopoietic cells by the P210 BCR/ABL oncogene product of the Philadelphia chromosome.

Characterization of the BCR promoter in Philadelphia chromosome-positive and -negative cell lines.

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