Effects of complementarity determining region mutations on the affinity of an alpha/beta T cell receptor: measuring the energy associated with CD4/CD8 repertoire skewing
about
Selection of functional T cell receptor mutants from a yeast surface-display libraryNatural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognitionIn vitro evolution of a T cell receptor with high affinity for peptide/MHC.Molecular interactions between extracellular components of the T-cell receptor signaling complex.Two mechanisms that account for major histocompatibility complex restriction of T cells.Role of 2CT cell receptor residues in the binding of self- and allo-major histocompatibility complexesMapping the energy of superantigen Staphylococcus enterotoxin C3 recognition of an alpha/beta T cell receptor using alanine scanning mutagenesis.Single and dual amino acid substitutions in TCR CDRs can enhance antigen-specific T cell functions.Evolutionarily conserved amino acids that control TCR-MHC interaction.A structural voyage toward an understanding of the MHC-I-restricted immune response: lessons learned and much to be learned.Identification of a Titin-derived HLA-A1-presented peptide as a cross-reactive target for engineered MAGE A3-directed T cells.Subtle changes in TCRα CDR1 profoundly increase the sensitivity of CD4 T cellsEfficient T cell activation requires an optimal dwell-time of interaction between the TCR and the pMHC complex.The CDR3 regions of an immunodominant T cell receptor dictate the 'energetic landscape' of peptide-MHC recognition
P2860
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P2860
Effects of complementarity determining region mutations on the affinity of an alpha/beta T cell receptor: measuring the energy associated with CD4/CD8 repertoire skewing
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Effects of complementarity det ...... ith CD4/CD8 repertoire skewing
@ast
Effects of complementarity det ...... ith CD4/CD8 repertoire skewing
@en
type
label
Effects of complementarity det ...... ith CD4/CD8 repertoire skewing
@ast
Effects of complementarity det ...... ith CD4/CD8 repertoire skewing
@en
prefLabel
Effects of complementarity det ...... ith CD4/CD8 repertoire skewing
@ast
Effects of complementarity det ...... ith CD4/CD8 repertoire skewing
@en
P2093
P2860
P356
P1476
Effects of complementarity det ...... ith CD4/CD8 repertoire skewing
@en
P2093
P2860
P304
P356
10.1084/JEM.189.3.461
P407
P577
1999-02-01T00:00:00Z