Early events in DNA replication require cyclin E and are blocked by p21CIP1. - Wikidata - awgldk - TriplyDB

Early events in DNA replication require cyclin E and are blocked by p21CIP1.

Early events in DNA replication require cyclin E and are blocked by p21CIP1.

http://www.wikidata.org/entity/Q36382696

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Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells The cell cycle regulator p27Kip1 interacts with MCM7, a DNA replication licensing factor, to inhibit initiation of DNA replication Plk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP-dependent destruction of the APC Inhibitor Emi1 Cyclin-binding motifs are essential for the function of p21CIP1 Negative regulation of DNA replication by the retinoblastoma protein is mediated by its association with MCM7.Xenopus Cdc45-dependent loading of DNA polymerase alpha onto chromatin under the control of S-phase Cdk.Mutations of the Drosophila dDP, dE2F, and cyclin E genes reveal distinct roles for the E2F-DP transcription factor and cyclin E during the G1-S transition.A dual role of cyclin E in cell proliferation and apoptosis may provide a target for cancer therapy Nonperiodic activity of the human anaphase-promoting complex-Cdh1 ubiquitin ligase results in continuous DNA synthesis uncoupled from mitosis Changes in association of the Xenopus origin recognition complex with chromatin on licensing of replication origins NPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcription Endoreplication: polyploidy with purpose Cyclin-dependent kinase control of centrosome duplication Chromosome association of minichromosome maintenance proteins in Drosophila endoreplication cycles The DP-1 transcription factor is required for keratinocyte growth and epidermal stratification Novel roles for p53 in the genesis and targeting of tetraploid cancer cells Components of an SCF ubiquitin ligase localize to the centrosome and regulate the centrosome duplication cycle Esthesioneuroblastoma: reflections of a 21-year experience.A requirement for replication in activation of the ATR-dependent DNA damage checkpoint.Protein phosphatase 2A regulates binding of Cdc45 to the prereplication complex.ATR and ATM regulate the timing of DNA replication origin firing.Wee1 kinase alters cyclin E/Cdk2 and promotes apoptosis during the early embryonic development of Xenopus laevis Lithocholic Acid Hydroxyamide Destabilizes Cyclin D1 and Induces G0/G1 Arrest by Inhibiting Deubiquitinase USP2a Initiation of DNA replication in eukaryotes: questioning the origin.Alternating oscillations and chaos in a model of two coupled biochemical oscillators driving successive phases of the cell cycle.Discovery of a distinct domain in cyclin A sufficient for centrosomal localization independently of Cdk binding.Initiation of DNA replication after fertilization is regulated by p90Rsk at pre-RC/pre-IC transition in starfish eggs.In vivo accumulation of cyclin A and cellular replication factors in autonomous parvovirus minute virus of mice-associated replication bodies.Differential control of transcription by DNA-bound cyclins.Role of replication protein A as sensor in activation of the S-phase checkpoint in Xenopus egg extracts.Global absolute quantification reveals tight regulation of protein expression in single Xenopus eggs.Proteolytic cleavage of cyclin E leads to inactivation of associated kinase activity and amplification of apoptosis in hematopoietic cells.Identification of the nuclear localization signal in Xenopus cyclin E and analysis of its role in replication and mitosis.Inhibition of S-phase cyclin-dependent kinase activity blocks expression of Epstein-Barr virus immediate-early and early genes, preventing viral lytic replication Dissection of the XChk1 signaling pathway in Xenopus laevis embryos.Two for two: Cdk2 and its role in centrosome doubling.Nuclear accumulation of cyclin E/Cdk2 triggers a concentration-dependent switch for the destruction of p27Xic1.The function of Xenopus Bloom's syndrome protein homolog (xBLM) in DNA replication Interaction of a cyclin E fragment with Ku70 regulates Bax-mediated apoptosis.Cyclins E1 and E2 are required for endoreplication in placental trophoblast giant cells

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P2860

Early events in DNA replication require cyclin E and are blocked by p21CIP1.

http://www.wikidata.org/entity/Q36382696

description

1995 nî lūn-bûn

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1995年の論文

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1995年学术文章

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1995年学术文章

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1995年学术文章

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1995年学术文章

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1995年学术文章

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1995年學術文章

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1995年學術文章

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1995年學術文章

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name

Early events in DNA replication require cyclin E and are blocked by p21CIP1.

@ast

Early events in DNA replication require cyclin E and are blocked by p21CIP1.

@en

type

label

Early events in DNA replication require cyclin E and are blocked by p21CIP1.

@ast

Early events in DNA replication require cyclin E and are blocked by p21CIP1.

@en

prefLabel

Early events in DNA replication require cyclin E and are blocked by p21CIP1.

@ast

Early events in DNA replication require cyclin E and are blocked by p21CIP1.

@en

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P1476

Early events in DNA replication require cyclin E and are blocked by p21CIP1.

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P2093

M Philippe

http://www.w3.org/2001/XMLSchema#string

M W Kirschner

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P K Jackson

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S Chevalier

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P2860

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

Cyclin A is required at two points in the human cell cycle

p13suc1 acts in the fission yeast cell division cycle as a component of the p34cdc2 protein kinase

Human cyclin E, a nuclear protein essential for the G1-to-S phase transition

Steps in the assembly of replication-competent nuclei in a cell-free system from Xenopus eggs

WAF1, a potential mediator of p53 tumor suppression

Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle

Reconstitution of complete SV40 DNA replication with purified replication factors

p21 is a universal inhibitor of cyclin kinases

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755-769

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10.1083/JCB.130.4.755

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4

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130

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2199964

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