Voltage-dependent block by saxitoxin of sodium channels incorporated into planar lipid bilayers
about
Folding similarity of the outer pore region in prokaryotic and eukaryotic sodium channels revealed by docking of conotoxins GIIIA, PIIIA, and KIIIA in a NavAb-based model of Nav1.4.The saxitoxin/tetrodotoxin binding site on cloned rat brain IIa Na channels is in the transmembrane electric field.Fast lidocaine block of cardiac and skeletal muscle sodium channels: one site with two routes of access.Lipid surface charge does not influence conductance or calcium block of single sodium channels in planar bilayers.Competitive binding interaction between Zn2+ and saxitoxin in cardiac Na+ channels. Evidence for a sulfhydryl group in the Zn2+/saxitoxin binding site.Differences in saxitoxin and tetrodotoxin binding revealed by mutagenesis of the Na+ channel outer vestibule.Saxitoxin blocks batrachotoxin-modified sodium channels in the node of Ranvier in a voltage-dependent manner.Influence of negative surface charge on toxin binding to canine heart Na channels in planar bilayers.Voltage-dependent activation in purified reconstituted sodium channels from rabbit T-tubular membranes.Use-dependent block of the voltage-gated Na(+) channel by tetrodotoxin and saxitoxin: effect of pore mutations that change ionic selectivity.An ion's view of the potassium channel. The structure of the permeation pathway as sensed by a variety of blocking ions.Single Na+ channels activated by veratridine and batrachotoxinBatrachotoxin-modified sodium channels in planar lipid bilayers. Characterization of saxitoxin- and tetrodotoxin-induced channel closures.Batrachotoxin-modified sodium channels from squid optic nerve in planar bilayers. Ion conduction and gating propertiesOn the interaction of bovine pancreatic trypsin inhibitor with maxi Ca(2+)-activated K+ channels. A model system for analysis of peptide-induced subconductance states.Ion permeation, divalent ion block, and chemical modification of single sodium channels. Description by single- and double-occupancy rate-theory models.Trimethyloxonium modification of single batrachotoxin-activated sodium channels in planar bilayers. Changes in unit conductance and in block by saxitoxin and calciumInteractions of divalent cations with single calcium channels from rat brain synaptosomes.Voltage-dependent blockade of muscle Na+ channels by guanidinium toxinsEffects of membrane surface charge and calcium on the gating of rat brain sodium channels in planar bilayers.Single-channel properties of the reconstituted voltage-regulated Na channel isolated from the electroplax of Electrophorus electricusFunctional reconstitution of the purified brain sodium channel in planar lipid bilayers.The tetrodotoxin binding site is within the outer vestibule of the sodium channel.Blocking mechanisms of batrachotoxin-activated Na channels in artificial bilayers.The sodium channel of excitable and non-excitable cells.Conotoxins as sensors of local pH and electrostatic potential in the outer vestibule of the sodium channel.
P2860
Q30586316-953C02D0-5884-4BD5-8892-74BE516E502BQ34018495-D0AEAF25-0CB1-44D0-8887-3BFD9A539B16Q34019295-8353CE96-35A7-42D7-9AE2-6BA096C44711Q34088758-A4C77F3F-8A0A-4588-A9C6-ED085B4BC2BEQ34127152-F2C9E9C3-33FF-484A-A593-DF0094343CE4Q34169482-BF1CE148-D04A-4A8C-A257-8E53D893AD04Q34257606-FC014733-4D25-4593-9770-7B4678D24277Q34261258-B98C6EEC-E6BC-44EC-99D4-5BB4027406DFQ35587078-5DCE1BEC-41A5-4FF3-B28F-130EBD6ADBC2Q36277894-D50DD4FE-863B-4231-9F27-2D63FCD550BFQ36409428-DE0CD861-7EEC-4C22-A0FB-17C96E9C8C05Q36409597-27CF6292-F4EA-4F55-9E15-F05A82FC6F18Q36409710-4DA52529-4551-4832-86F2-558D0642BE7EQ36410145-7CEEF761-3EC3-46D9-BD18-F7FBD767F65BQ36410925-43816D1B-3941-4284-8A60-E98E28D2ABF5Q36411457-F71B257B-AEF3-4B57-AE35-C652B4BC06FAQ36412797-24A7D01C-44DD-4033-8818-2F1B148CA07DQ36412816-2E644A55-4F8E-40BD-B8FC-CACA8A5DD884Q36433613-DBAF057D-6E0D-43B5-8F40-F29EB7D43508Q36434197-43BF3D64-08D3-409E-BF3B-5F2D05778D15Q37567030-2A457B84-3DA4-4D7F-B718-FAA36131491BQ37673020-0F124DCA-9B5B-4EA6-8091-D2781A3821AEQ37730498-19820245-E149-4C0F-A1E7-AEAEF1AD1A38Q38166410-1B046492-69A2-4733-9285-659D14C0E450Q38186803-050F7C3B-6105-4619-BDCA-DF46191D6E9DQ41953808-2409D7ED-9CD9-4B48-9AB7-31B697EB2FD3
P2860
Voltage-dependent block by saxitoxin of sodium channels incorporated into planar lipid bilayers
description
1984 nî lūn-bûn
@nan
1984 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1984 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1984年の論文
@ja
1984年論文
@yue
1984年論文
@zh-hant
1984年論文
@zh-hk
1984年論文
@zh-mo
1984年論文
@zh-tw
1984年论文
@wuu
name
Voltage-dependent block by sax ...... ted into planar lipid bilayers
@ast
Voltage-dependent block by sax ...... ted into planar lipid bilayers
@en
Voltage-dependent block by sax ...... ted into planar lipid bilayers
@nl
type
label
Voltage-dependent block by sax ...... ted into planar lipid bilayers
@ast
Voltage-dependent block by sax ...... ted into planar lipid bilayers
@en
Voltage-dependent block by sax ...... ted into planar lipid bilayers
@nl
prefLabel
Voltage-dependent block by sax ...... ted into planar lipid bilayers
@ast
Voltage-dependent block by sax ...... ted into planar lipid bilayers
@en
Voltage-dependent block by sax ...... ted into planar lipid bilayers
@nl
P2093
P2860
P1433
P1476
Voltage-dependent block by sax ...... ted into planar lipid bilayers
@en
P2093
B K Krueger
J F Worley
R J French
P2860
P304
P356
10.1016/S0006-3495(84)84156-9
P407
P577
1984-01-01T00:00:00Z