Three scrapie prion isolates exhibit different accumulation patterns of the prion protein scrapie isoform
about
Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteinsPrionsAnalysis of prion strains by PrPSc profiling in sporadic Creutzfeldt-Jakob disease.Distinct PrP properties suggest the molecular basis of strain variation in transmissible mink encephalopathy.Levels of the Mahogunin Ring Finger 1 E3 ubiquitin ligase do not influence prion diseaseComputational approaches to shed light on molecular mechanisms in biological processesFatal familial insomnia and familial Creutzfeldt-Jakob disease: different prion proteins determined by a DNA polymorphism.Prion isolate specified allotypic interactions between the cellular and scrapie prion proteins in congenic and transgenic mice.Etiology and pathogenesis of prion diseases.Transmission of Creutzfeldt-Jakob disease from humans to transgenic mice expressing chimeric human-mouse prion protein.Cholesterol depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit formation of the scrapie isoform.PrPSc formation and clearance as determinants of prion tropism.The interpretation of disease phenotypes to identify TSE strains following murine bioassay: characterisation of classical scrapie.Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-PrP antibodies.Prion strain discrimination in cell culture: the cell panel assayIdentification of a prion protein epitope modulating transmission of bovine spongiform encephalopathy prions to transgenic mice.Prion strain targeting independent of strain-specific neuronal tropism.Identification of clinical target areas in the brainstem of prion-infected mice.The region approximately between amino acids 81 and 137 of proteinase K-resistant PrPSc is critical for the infectivity of the Chandler prion strain.The effects of prion protein proteolysis and disaggregation on the strain properties of hamster scrapie.Prion Disease Induces Alzheimer Disease-Like Neuropathologic Changes.PET-blot analysis contributes to BSE strain recognition in C57Bl/6 mice.Astrocyte signaling and neurodegeneration: new insights into CNS disorders.The standard scrapie cell assay: development, utility and prospects.Pathology and immunocytochemistry of a kuru brain.Fatal familial insomnia and familial Creutzfeldt-Jakob disease: clinical, pathological and molecular features.Prion protein transgenes and the neuropathology in prion diseases.Human anti-prion antibodies block prion peptide fibril formation and neurotoxicity.Transport of prion protein across the blood-brain barrier.Evidence for the conformation of the pathologic isoform of the prion protein enciphering and propagating prion diversity.Discriminating scrapie and bovine spongiform encephalopathy isolates by infrared spectroscopy of pathological prion protein.Synaptic prion protein immuno-reactivity in the rodent cerebellum.
P2860
Q24564014-F42E3B90-C9FC-4089-97F5-945978968704Q24633319-1A0DF58B-0443-4E2A-9255-182B1BAB8F0DQ24812893-D41D12C0-0B84-43B6-8BF4-7CE88C637D90Q30420123-2BF95D57-D8C0-461D-8968-4299297588EDQ34576746-03197B81-F15C-4CA1-BBD9-B769D4FB34F0Q34671563-6A94D96A-B85B-4D61-95E4-2B617FB93EDDQ35138028-66FC73DB-4216-4277-B0EC-FB109769FB17Q35523444-BDC0D2F2-65C3-4040-8F5B-D05D8B12C19AQ35795039-C705B8BA-FCD7-433F-B32F-AB9B909A9D21Q35823555-6D5ABB69-E3A1-4232-8508-E624A2494F17Q36235271-6696BCE7-E779-45BB-907D-8F498746E06DQ36326862-24C241D2-F84A-4825-ADA3-DD19567C436AQ36416046-AF1899D4-877A-49DA-95ED-68F51CA173B5Q36663046-33914AE6-42E8-48BC-AA47-CBA85ECD5339Q36693359-64666D38-4862-4B1A-82FE-96E3230FF59EQ36806018-3623D8B6-0545-433A-B802-E34B04CA9C86Q37033154-BC62EB8B-CB7F-4FAC-ABAF-73AB9BFFCE9CQ37105695-4916CF91-4228-4699-A342-E46A3B38D6CBQ37145304-D0332C61-8523-41F9-9143-F124EBC4BB86Q37174326-0F9DB530-6F32-4868-A7A3-7A27F54AA2F3Q37391447-CD252B1C-35CD-407C-86CD-C0442D12F471Q37643561-4147EC4F-FAFA-4F69-B1C4-3EF8C7DAAEECQ38055136-1D1DD95D-3CB6-4CD0-B52B-24192A701243Q38324712-3A5A07DA-DC16-4E96-8A57-DF9998A4972FQ38476222-F7247C29-124B-450C-9E76-603826CB9F80Q40537014-0EF05A04-6850-449F-A4FB-B9ECCD2AA7A2Q40537035-50882CCD-F628-48B3-9BF9-B935F0916F04Q41975386-42374D2B-B8B1-400B-BA8C-74A4C7B74EB0Q41979008-35B99360-21D1-459E-A3DB-D7052FB3F8E7Q46433690-2CCBC98E-9A32-4BC7-AE7E-587DE201DBE9Q47448298-ECF96FF8-3F63-4D76-B7F4-0D17648310BEQ54046641-07045320-9334-4BEC-8205-7BD7C14E27EF
P2860
Three scrapie prion isolates exhibit different accumulation patterns of the prion protein scrapie isoform
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
Three scrapie prion isolates e ...... prion protein scrapie isoform
@ast
Three scrapie prion isolates e ...... prion protein scrapie isoform
@en
type
label
Three scrapie prion isolates e ...... prion protein scrapie isoform
@ast
Three scrapie prion isolates e ...... prion protein scrapie isoform
@en
prefLabel
Three scrapie prion isolates e ...... prion protein scrapie isoform
@ast
Three scrapie prion isolates e ...... prion protein scrapie isoform
@en
P2093
P2860
P356
P1476
Three scrapie prion isolates e ...... prion protein scrapie isoform
@en
P2093
P2860
P304
P356
10.1073/PNAS.90.14.6449
P407
P577
1993-07-01T00:00:00Z