The X11 proteins, Abeta production and Alzheimer's disease.
about
Growth arrest-specific 1 binds to and controls the maturation and processing of the amyloid-beta precursor proteinMint3 enhances the activity of hypoxia-inducible factor-1 (HIF-1) in macrophages by suppressing the activity of factor inhibiting HIF-1An X11alpha/FSBP complex represses transcription of the GSK3beta gene promoterTrafficking regulation of proteins in Alzheimer's diseaseTandem SAM Domain Structure of Human Caskin1: A Presynaptic, Self-Assembling Scaffold for CASKTrafficking and proteolytic processing of APPDeficiency of the copper chaperone for superoxide dismutase increases amyloid-β productionAmyloid precursor protein trafficking, processing, and functionCalsyntenin-1 shelters APP from proteolytic processing during anterograde axonal transport.Identification of novel candidate genes for Alzheimer's disease by autozygosity mapping using genome wide SNP dataCalsyntenin-1 mediates axonal transport of the amyloid precursor protein and regulates Aβ productionGenetic pathway-based hierarchical clustering analysis of older adults with cognitive complaints and amnestic mild cognitive impairment using clinical and neuroimaging phenotypes.Dendritic spine dynamics--a key role for kalirin-7.Aberrant methylation of gene associated CpG sites occurs in borderline personality disorder.Synaptic autoregulation by metalloproteases and γ-secretase.Serotonin 6 receptor controls Alzheimer's disease and depressionSubstrate specificity of gamma-secretase and other intramembrane proteases.Genetic loci modulating amyloid-beta levels in a mouse model of Alzheimer's disease.Neuronal protein trafficking associated with Alzheimer disease: from APP and BACE1 to glutamate receptorsRegulation of amyloid beta-protein precursor by phosphorylation and protein interactions.X11alpha haploinsufficiency enhances Abeta amyloid deposition in Alzheimer's disease transgenic mice.X11beta rescues memory and long-term potentiation deficits in Alzheimer's disease APPswe Tg2576 mice.Placental DNA methylation alterations associated with maternal tobacco smoking at the RUNX3 gene are also associated with gestational age.Membrane rafts in Alzheimer's disease beta-amyloid production.Regulation of β cleavage of amyloid precursor proteinIntracellular trafficking of the β-secretase and processing of amyloid precursor protein.The physiology of the β-amyloid precursor protein intracellular domain AICD.Deletion of the Mint3/Apba3 gene in mice abrogates macrophage functions and increases resistance to lipopolysaccharide-induced septic shock.Structure and Synaptic Function of Metal Binding to the Amyloid Precursor Protein and its Proteolytic Fragments.Integrated functions of membrane-type 1 matrix metalloproteinase in regulating cancer malignancy: Beyond a proteinase.Adaptor protein sorting nexin 17 regulates amyloid precursor protein trafficking and processing in the early endosomes.Phosphorylation of the amino-terminal region of X11L regulates its interaction with APP.X11 proteins regulate the translocation of amyloid beta-protein precursor (APP) into detergent-resistant membrane and suppress the amyloidogenic cleavage of APP by beta-site-cleaving enzyme in brain.Increased amyloidogenic processing of transgenic human APP in X11-like deficient mouse brain.APP dimer formation is initiated in the endoplasmic reticulum and differs between APP isoforms.Expression of the neuronal adaptor protein X11alpha protects against memory dysfunction in a transgenic mouse model of Alzheimer's disease.M344 promotes nonamyloidogenic amyloid precursor protein processing while normalizing Alzheimer's disease genes and improving memory.The memory enhancing effect of the APP-derived tripeptide Ac-rER is mediated through CRMP2.Amyloid precursor protein traffics from the Golgi directly to early endosomes in an Arl5b- and AP4-dependent pathway.GULP1 is a novel APP-interacting protein that alters APP processing.
P2860
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P2860
The X11 proteins, Abeta production and Alzheimer's disease.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
The X11 proteins, Abeta production and Alzheimer's disease.
@ast
The X11 proteins, Abeta production and Alzheimer's disease.
@en
type
label
The X11 proteins, Abeta production and Alzheimer's disease.
@ast
The X11 proteins, Abeta production and Alzheimer's disease.
@en
prefLabel
The X11 proteins, Abeta production and Alzheimer's disease.
@ast
The X11 proteins, Abeta production and Alzheimer's disease.
@en
P50
P1476
The X11 proteins, Abeta production and Alzheimer's disease
@en
P2093
Maria E Tennant
P304
P356
10.1016/J.TINS.2006.03.001
P577
2006-03-20T00:00:00Z