Dual effects of ADP and adenylylimidodiphosphate on CFTR channel kinetics show binding to two different nucleotide binding sites.
about
Channelrhodopsin-2, a directly light-gated cation-selective membrane channelCFTR gating I: Characterization of the ATP-dependent gating of a phosphorylation-independent CFTR channel (DeltaR-CFTR).CFTR channel gating: incremental progress in irreversible steps.Non-specific activation of the epithelial sodium channel by the CFTR chloride channelADP inhibits function of the ABC transporter cystic fibrosis transmembrane conductance regulator via its adenylate kinase activity.On the mechanism of CFTR inhibition by a thiazolidinone derivative.A conditional probability analysis of cystic fibrosis transmembrane conductance regulator gating indicates that ATP has multiple effects during the gating cycle.Potent stimulation and inhibition of the CFTR Cl(-) current by phloxine B.Mutating the Conserved Q-loop Glutamine 1291 Selectively Disrupts Adenylate Kinase-dependent Channel Gating of the ATP-binding Cassette (ABC) Adenylate Kinase Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) and Reduces Channel Function inAdenylate kinase activity in ABC transporters.On the mechanism of MgATP-dependent gating of CFTR Cl- channelsSevered channels probe regulation of gating of cystic fibrosis transmembrane conductance regulator by its cytoplasmic domainsApplication of high-resolution single-channel recording to functional studies of cystic fibrosis mutants.CLC-0 and CFTR: chloride channels evolved from transporters.Regulation of CFTR Cl- channel gating by ATP binding and hydrolysis.Gating of the CFTR Cl- channel by ATP-driven nucleotide-binding domain dimerisation.The gating of the CFTR channel.Protein kinase-independent activation of CFTR by phosphatidylinositol phosphates.Functionally similar vanadate-induced 8-azidoadenosine 5'-[alpha-(32)P]Diphosphate-trapped transition state intermediates of human P-glycoprotin are generated in the absence and presence of ATP hydrolysis.Two mechanisms of genistein inhibition of cystic fibrosis transmembrane conductance regulator Cl- channels expressed in murine cell line.Involvement of F1296 and N1303 of CFTR in induced-fit conformational change in response to ATP binding at NBD2Deletion of phenylalanine 508 causes attenuated phosphorylation-dependent activation of CFTR chloride channels.Voltage-dependent flickery block of an open cystic fibrosis transmembrane conductance regulator (CFTR) channel pore.Mutation of Walker-A lysine 464 in cystic fibrosis transmembrane conductance regulator reveals functional interaction between its nucleotide-binding domains.Mutations that change the position of the putative gamma-phosphate linker in the nucleotide binding domains of CFTR alter channel gating.Nucleoside triphosphate pentose ring impact on CFTR gating and hydrolysis.Apparent affinity of CFTR for ATP is increased by continuous kinase activity.Inhibition of CFTR channels by a peptide toxin of scorpion venom.NM23 proteins: innocent bystanders or local energy boosters for CFTR?Voltage-sensitive gating induced by a mutation in the fifth transmembrane domain of CFTR.Mechanism of electrogenic cation transport by the cloned organic cation transporter 2 from rat.CFTR fails to inhibit the epithelial sodium channel ENaC expressed in Xenopus laevis oocytes.Sites associated with Kalydeco binding on human Cystic Fibrosis Transmembrane Conductance Regulator revealed by Hydrogen/Deuterium Exchange.
P2860
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P2860
Dual effects of ADP and adenylylimidodiphosphate on CFTR channel kinetics show binding to two different nucleotide binding sites.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Dual effects of ADP and adenyl ...... rent nucleotide binding sites.
@ast
Dual effects of ADP and adenyl ...... rent nucleotide binding sites.
@en
type
label
Dual effects of ADP and adenyl ...... rent nucleotide binding sites.
@ast
Dual effects of ADP and adenyl ...... rent nucleotide binding sites.
@en
prefLabel
Dual effects of ADP and adenyl ...... rent nucleotide binding sites.
@ast
Dual effects of ADP and adenyl ...... rent nucleotide binding sites.
@en
P2093
P2860
P356
P1476
Dual effects of ADP and adenyl ...... rent nucleotide binding sites.
@en
P2093
P2860
P356
10.1085/JGP.114.1.55
P577
1999-07-01T00:00:00Z