Phosphorylation of titin modulates passive stiffness of cardiac muscle in a titin isoform-dependent manner. - Wikidata - awgldk - TriplyDB

Phosphorylation of titin modulates passive stiffness of cardiac muscle in a titin isoform-dependent manner.

Phosphorylation of titin modulates passive stiffness of cardiac muscle in a titin isoform-dependent manner.

http://www.wikidata.org/entity/Q36445698

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Scaffold Proteins Regulating Extracellular Regulated Kinase Function in Cardiac Hypertrophy and Disease Titin-based tension in the cardiac sarcomere: molecular origin and physiological adaptations Heart failure with preserved ejection fraction Diastolic dysfunction Tetrahydrobiopterin improves diastolic dysfunction by reversing changes in myofilament properties Heart failure with preserved ejection fraction.Mutation that dramatically alters rat titin isoform expression and cardiomyocyte passive tension The increase in non-cross-bridge forces after stretch of activated striated muscle is related to titin isoforms Excision of titin's cardiac PEVK spring element abolishes PKCalpha-induced increases in myocardial stiffness Heart failure with preserved ejection fraction: molecular pathways of the aging myocardium Physiologic basis and pathophysiologic implications of the diastolic properties of the cardiac muscle Calcium sensitivity and the Frank-Starling mechanism of the heart are increased in titin N2B region-deficient mice Phosphoprotein abundance changes in hypertensive cardiac remodeling.Disuse-induced preferential loss of the giant protein titin depresses muscle performance via abnormal sarcomeric organization.A force-activated kinase in a catch smooth muscle.Contribution of titin and extracellular matrix to passive pressure and measurement of sarcomere length in the mouse left ventricle.The giant protein titin: a regulatory node that integrates myocyte signaling pathways.Cardiac titin and heart disease.Muscle giants: molecular scaffolds in sarcomerogenesis.Hyperphosphorylation of mouse cardiac titin contributes to transverse aortic constriction-induced diastolic dysfunction Identification of the Acetylation and Ubiquitin-Modified Proteome during the Progression of Skeletal Muscle Atrophy.Magnitude of length-dependent changes in contractile properties varies with titin isoform in rat ventricles.Modulation of cardiac function: titin springs into action.Development of dilated cardiomyopathy in Bmal1-deficient mice A novel mechanism involving four-and-a-half LIM domain protein-1 and extracellular signal-regulated kinase-2 regulates titin phosphorylation and mechanics.Phosphorylating Titin's Cardiac N2B Element by ERK2 or CaMKIIδ Lowers the Single Molecule and Cardiac Muscle Force The multifunctional Ca(2+)/calmodulin-dependent protein kinase II delta (CaMKIIδ) phosphorylates cardiac titin's spring elements.Titin is a major human disease gene.Global comparison of phosphoproteins in human and rodent hearts: implications for translational studies of myosin light chain and troponin phosphorylations.Titin-based stiffening of muscle fibers in Ehlers-Danlos Syndrome Sarcomere length dependence of power output is increased after PKA treatment in rat cardiac myocytes Protein kinase A-dependent modulation of Ca2+ sensitivity in cardiac and fast skeletal muscles after reconstitution with cardiac troponin.Modulation of titin-based stiffness by disulfide bonding in the cardiac titin N2-B unique sequence The cAMP binding protein Epac regulates cardiac myofilament function.Tuning passive mechanics through differential splicing of titin during skeletal muscle development.PKC phosphorylation of titin's PEVK element: a novel and conserved pathway for modulating myocardial stiffness.Effects of contractile protein phosphorylation on force development in permeabilized rat cardiac myocytes.Titin and troponin: central players in the frank-starling mechanism of the heart.Cardiac titin: a multifunctional giant Conformation-regulated mechanosensory control via titin domains in cardiac muscle.

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P2860

Phosphorylation of titin modulates passive stiffness of cardiac muscle in a titin isoform-dependent manner.

http://www.wikidata.org/entity/Q36445698

description

2005 nî lūn-bûn

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2005年の論文

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2005年学术文章

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2005年学术文章

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2005年學術文章

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2005年學術文章

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2005年學術文章

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name

Phosphorylation of titin modul ...... itin isoform-dependent manner.

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type

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Phosphorylation of titin modul ...... itin isoform-dependent manner.

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Phosphorylation of titin modul ...... itin isoform-dependent manner.

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Phosphorylation of titin modul ...... itin isoform-dependent manner.

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Phosphorylation of titin modul ...... itin isoform-dependent manner.

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The Journal of General Physiology

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Phosphorylation of titin modul ...... itin isoform-dependent manner.

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Henk L Granzier

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Norio Fukuda

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Preetha Nair

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Yiming Wu

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P2860

Titin-actin interaction in mouse myocardium: passive tension modulation and its regulation by calcium/S100A1

Cardiac excitation-contraction coupling

Effect of stimulation rate, sarcomere length and Ca(2+) on force generation by mouse cardiac muscle.

Lack of effect of isoproterenol on unloaded velocity of sarcomere shortening in rat cardiac trabeculae.

Muscle assembly: a titanic achievement?

Passive tension in cardiac muscle: contribution of collagen, titin, microtubules, and intermediate filaments

Molecular basis of passive stress relaxation in human soleus fibers: assessment of the role of immunoglobulin-like domain unfolding.

Altered titin expression, myocardial stiffness, and left ventricular function in patients with dilated cardiomyopathy.

Passive stiffness changes caused by upregulation of compliant titin isoforms in human dilated cardiomyopathy hearts.

Cardiac titin: an adjustable multi-functional spring.

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10.1085/JGP.200409177

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3

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125

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2005-03-01T00:00:00Z

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15738048

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phosphorylation

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2234012

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