Phosphorylation of titin modulates passive stiffness of cardiac muscle in a titin isoform-dependent manner.
about
Scaffold Proteins Regulating Extracellular Regulated Kinase Function in Cardiac Hypertrophy and DiseaseTitin-based tension in the cardiac sarcomere: molecular origin and physiological adaptationsHeart failure with preserved ejection fractionDiastolic dysfunctionTetrahydrobiopterin improves diastolic dysfunction by reversing changes in myofilament propertiesHeart failure with preserved ejection fraction.Mutation that dramatically alters rat titin isoform expression and cardiomyocyte passive tensionThe increase in non-cross-bridge forces after stretch of activated striated muscle is related to titin isoformsExcision of titin's cardiac PEVK spring element abolishes PKCalpha-induced increases in myocardial stiffnessHeart failure with preserved ejection fraction: molecular pathways of the aging myocardiumPhysiologic basis and pathophysiologic implications of the diastolic properties of the cardiac muscleCalcium sensitivity and the Frank-Starling mechanism of the heart are increased in titin N2B region-deficient micePhosphoprotein abundance changes in hypertensive cardiac remodeling.Disuse-induced preferential loss of the giant protein titin depresses muscle performance via abnormal sarcomeric organization.A force-activated kinase in a catch smooth muscle.Contribution of titin and extracellular matrix to passive pressure and measurement of sarcomere length in the mouse left ventricle.The giant protein titin: a regulatory node that integrates myocyte signaling pathways.Cardiac titin and heart disease.Muscle giants: molecular scaffolds in sarcomerogenesis.Hyperphosphorylation of mouse cardiac titin contributes to transverse aortic constriction-induced diastolic dysfunctionIdentification of the Acetylation and Ubiquitin-Modified Proteome during the Progression of Skeletal Muscle Atrophy.Magnitude of length-dependent changes in contractile properties varies with titin isoform in rat ventricles.Modulation of cardiac function: titin springs into action.Development of dilated cardiomyopathy in Bmal1-deficient miceA novel mechanism involving four-and-a-half LIM domain protein-1 and extracellular signal-regulated kinase-2 regulates titin phosphorylation and mechanics.Phosphorylating Titin's Cardiac N2B Element by ERK2 or CaMKIIδ Lowers the Single Molecule and Cardiac Muscle ForceThe multifunctional Ca(2+)/calmodulin-dependent protein kinase II delta (CaMKIIδ) phosphorylates cardiac titin's spring elements.Titin is a major human disease gene.Global comparison of phosphoproteins in human and rodent hearts: implications for translational studies of myosin light chain and troponin phosphorylations.Titin-based stiffening of muscle fibers in Ehlers-Danlos SyndromeSarcomere length dependence of power output is increased after PKA treatment in rat cardiac myocytesProtein kinase A-dependent modulation of Ca2+ sensitivity in cardiac and fast skeletal muscles after reconstitution with cardiac troponin.Modulation of titin-based stiffness by disulfide bonding in the cardiac titin N2-B unique sequenceThe cAMP binding protein Epac regulates cardiac myofilament function.Tuning passive mechanics through differential splicing of titin during skeletal muscle development.PKC phosphorylation of titin's PEVK element: a novel and conserved pathway for modulating myocardial stiffness.Effects of contractile protein phosphorylation on force development in permeabilized rat cardiac myocytes.Titin and troponin: central players in the frank-starling mechanism of the heart.Cardiac titin: a multifunctional giantConformation-regulated mechanosensory control via titin domains in cardiac muscle.
P2860
Q26765993-3088D900-62E0-49DF-BC6A-4864ECBB4723Q26996063-8D7EBCB3-E3B8-49B7-B9EB-36B601A6A7CFQ27024008-4EA76300-DA96-4C13-AF66-14FF35C089FBQ28087715-F17EC89C-8D4A-49A1-8AC7-C11D559C7551Q28281608-CA3693A1-D41F-4405-A40D-FAFE8A77E617Q30420528-AC39B5ED-B29D-4AE6-AE3C-8A69356FF82CQ30482992-15ABD2AE-09C9-46F6-BBB3-146139586E7BQ30694133-52476BEB-EA5C-4EA3-8D66-637E493E83DCQ33787977-11206B2B-7EB8-4242-8AF1-8BA59E6D39BBQ33889242-8142E21C-D08D-4DF5-A266-FA773BFBEB57Q33961078-E386A595-7922-400F-9678-67051CCB3EE7Q34049988-0956585E-7FD1-4B50-B312-97C99F60AF48Q34289975-1EF5D621-F408-4DBB-AEC2-E956AA4FDEE6Q34586569-24CDE923-04DE-4B52-AB4B-252816D1B70EQ34635299-09C94FC3-4A4A-41AB-AA34-E99987CA78E6Q34673137-7B9F1821-0132-4C5C-A259-AF5C8C1FA24CQ34696141-1FCA7D53-874A-42DB-B7A3-559F399DBD56Q34721100-6BFCBE07-28D8-4912-8847-4BCC8AAB8D73Q34793699-E4814B4D-6BF6-4B37-805B-5E3B0AA6DBFCQ35316187-7E8FF52B-9BDF-415B-B8D6-9379C71F4236Q35753878-99CB06FD-F3F6-4161-9724-BDB721441DB6Q35964925-1FB756DA-4D5C-4138-88EA-31713D210909Q36057998-5DB5AE80-31A9-4F85-99B7-9DF12864E81FQ36176071-1A284AF6-B9B7-4786-AC55-52AA339B2016Q36215905-AD6BE628-ADC3-4CDE-9369-A8E8ED8915CCQ36429564-3EA14E76-BB8D-4B05-AB3C-1FB407E87904Q36504127-9558617D-F75A-43C7-BBB5-0EBB6FD8F839Q36675841-EF8B6218-9C8F-4E5E-811B-A5153D38AD47Q37026733-737BD5B5-74BE-4CBD-A877-D5940E43270CQ37174642-EF67E256-45EB-44CE-94B6-E2FB8A22999DQ37200169-98EB6398-5327-4772-9D33-6166314878EDQ37268151-C93F3967-6BE3-4FDB-9F31-3EBA591FE823Q37281915-45ABB575-C254-471C-A03E-386EF5B0E2DAQ37310787-268479C4-3FDC-4196-8EF6-D651B71EA04FQ37392633-86BFD330-F35F-4331-AD5D-AFD4E6B0AD70Q37394610-51C82F71-FA7E-4F51-98B9-56E1AA6D4334Q37428711-70821ED8-8486-4A58-9A0C-16B98AB58D01Q37740973-D447D143-5A44-4BA8-86B8-E49EDD0F09C0Q37755897-93CBC191-2D91-4852-890A-0B47CA69F8E0Q37846578-1BC77826-D497-4DCE-BBEB-2018A83249AC
P2860
Phosphorylation of titin modulates passive stiffness of cardiac muscle in a titin isoform-dependent manner.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Phosphorylation of titin modul ...... itin isoform-dependent manner.
@ast
Phosphorylation of titin modul ...... itin isoform-dependent manner.
@en
type
label
Phosphorylation of titin modul ...... itin isoform-dependent manner.
@ast
Phosphorylation of titin modul ...... itin isoform-dependent manner.
@en
prefLabel
Phosphorylation of titin modul ...... itin isoform-dependent manner.
@ast
Phosphorylation of titin modul ...... itin isoform-dependent manner.
@en
P2093
P2860
P356
P1476
Phosphorylation of titin modul ...... itin isoform-dependent manner.
@en
P2093
Henk L Granzier
Norio Fukuda
Preetha Nair
P2860
P304
P356
10.1085/JGP.200409177
P577
2005-03-01T00:00:00Z