Mutations in the 5' end of the human immunodeficiency virus type 1 polypurine tract affect RNase H cleavage specificity and virus titer.
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RNase H activity: structure, specificity, and function in reverse transcriptionMultiple nucleotide preferences determine cleavage-site recognition by the HIV-1 and M-MuLV RNases H.Effect of polypurine tract (PPT) mutations on human immunodeficiency virus type 1 replication: a virus with a completely randomized PPT retains low infectivity.Recent findings on the mechanisms involved in tenofovir resistance.Alternate polypurine tracts (PPTs) affect the rous sarcoma virus RNase H cleavage specificity and reveal a preferential cleavage following a GA dinucleotide sequence at the PPT-U3 junction.Mutations in the U5 sequences adjacent to the primer binding site do not affect tRNA cleavage by rous sarcoma virus RNase H but do cause aberrant integrations in vivoAlternate polypurine tracts affect rous sarcoma virus integration in vivo.SiRNA-induced mutation in HIV-1 polypurine tract region and its influence on viral fitness.Purine analog substitution of the HIV-1 polypurine tract primer defines regions controlling initiation of plus-strand DNA synthesis.Mutations in the human immunodeficiency virus type 1 polypurine tract (PPT) reduce the rate of PPT cleavage and plus-strand DNA synthesis.The effects of alternate polypurine tracts (PPTs) and mutations of sequences adjacent to the PPT on viral replication and cleavage specificity of the Rous sarcoma virus reverse transcriptase.Integration of rous sarcoma virus DNA: a CA dinucleotide is not required for integration of the U3 end of viral DNA.Effects of mutations in the G tract of the human immunodeficiency virus type 1 polypurine tract on virus replication and RNase H cleavageTwo modes of HIV-1 polypurine tract cleavage are affected by introducing locked nucleic acid analogs into the (-) DNA template.LEDGF/p75 Deficiency Increases Deletions at the HIV-1 cDNA Ends.The fourth central polypurine tract guides the synthesis of prototype foamy virus plus-strand DNA.
P2860
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P2860
Mutations in the 5' end of the human immunodeficiency virus type 1 polypurine tract affect RNase H cleavage specificity and virus titer.
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name
Mutations in the 5' end of the ...... e specificity and virus titer.
@ast
Mutations in the 5' end of the ...... e specificity and virus titer.
@en
type
label
Mutations in the 5' end of the ...... e specificity and virus titer.
@ast
Mutations in the 5' end of the ...... e specificity and virus titer.
@en
prefLabel
Mutations in the 5' end of the ...... e specificity and virus titer.
@ast
Mutations in the 5' end of the ...... e specificity and virus titer.
@en
P2093
P2860
P1433
P1476
Mutations in the 5' end of the ...... e specificity and virus titer.
@en
P2093
Edward Arnold
John G Julias
Stefan G Sarafianos
W Gregory Alvord
P2860
P304
11150-11157
P356
10.1128/JVI.77.20.11150-11157.2003
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P577
2003-10-01T00:00:00Z