Genetic findings in Parkinson's disease and translation into treatment: a leading role for mitochondria?
about
PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neuronsRelationships among molecular genetic and respiratory properties of Parkinson's disease cybrid cells show similarities to Parkinson's brain tissuesMitochondrial quality control: insights on how Parkinson's disease related genes PINK1, parkin, and Omi/HtrA2 interact to maintain mitochondrial homeostasis.Drosophila melanogaster in the study of human neurodegeneration.MitoPark mice mirror the slow progression of key symptoms and L-DOPA response in Parkinson's diseaseAntiinflammatory activity of melatonin in central nervous systemA time to reap, a time to sow: mitophagy and biogenesis in cardiac pathophysiologyAcute action of rotenone on nigral dopaminergic neurons--involvement of reactive oxygen species and disruption of Ca2+ homeostasis.Neuroprotective effects of aldehyde dehydrogenase 2 activation in rotenone-induced cellular and animal models of parkinsonismCorticotropin-Releasing Factor Receptor-1 Antagonism Reduces Oxidative Damage in an Alzheimer’s Disease Transgenic Mouse Model.Rotenone Susceptibility Phenotype in Olfactory Derived Patient Cells as a Model of Idiopathic Parkinson's DiseasePost-transcriptional regulation of mRNA associated with DJ-1 in sporadic Parkinson diseaseMitochondria in neuroplasticity and neurological disorders.Functional mechanism of neuroprotection by inhibitors of type B monoamine oxidase in Parkinson's disease.Pharmacological therapy in Parkinson's disease: focus on neuroprotection.Parkin, PINK1 and mitochondrial integrity: emerging concepts of mitochondrial dysfunction in Parkinson's disease.Synaptic protein alterations in Parkinson's disease.Mitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences.Adjunctive therapy in Parkinson's disease: the role of rasagiline.The possible involvement of mitochondrial dysfunctions in Lewy body dementia: a systematic review.PKA Phosphorylation of NCLX Reverses Mitochondrial Calcium Overload and Depolarization, Promoting Survival of PINK1-Deficient Dopaminergic NeuronsThe combination of lithium and l-Dopa/Carbidopa reduces MPTP-induced abnormal involuntary movements (AIMs) via calpain-1 inhibition in a mouse model: Relevance for Parkinson׳s disease therapy.A New Perspective for Parkinson's Disease: Circadian Rhythm.Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentationEffect of chronic L-dopa or melatonin treatments after dopamine deafferentation in rats: dyskinesia, motor performance, and cytological analysis.Abnormal visual gain control and excitotoxicity in early-onset Parkinson's disease Drosophila models.Mouse models of neurodegenerative disease: preclinical imaging and neurovascular component.Let-7d microRNA Attenuates 6-OHDA-Induced Injury by Targeting Caspase-3 in MN9D Cells.As a painkiller: a review of pre- and postnatal non-steroidal anti-inflammatory drug exposure effects on the nervous systems.An investigation into closed-loop treatment of neurological disorders based on sensing mitochondrial dysfunction.
P2860
Q24322788-227CAEF6-3A01-43C7-9CCF-29EA490DA654Q30437451-8A1240AE-8BBA-47DE-87DE-A9448A619B1FQ33603972-5B694417-48D6-436C-BBFD-883703588292Q34022667-3F2925D7-D7F5-4303-BFB6-5BB97FDE6F9CQ34133023-6A01C03B-5328-4E2F-A580-F8B36FA8099EQ34402174-5BA172C2-DCC3-4407-AECC-6AFC0E04ED8CQ34716974-26417D8E-FEC0-47FD-9398-C71F7466AD58Q35012808-67BE649E-4133-4070-8CE3-10FCE21C999AQ35557892-4225431F-DC89-4984-BC32-9E6FD8F8049DQ35801845-C6E9884E-15D5-4047-A502-7C076784311EQ36001692-C79B74E8-F52C-4BFB-869C-376286779046Q37093037-B565E173-BCCD-405E-8C5D-BEF8163DFF41Q37216404-BE7E0541-EDEB-4975-837C-A0FD40BF8DBDQ37578490-C89B51EE-746F-40B6-9B51-453C36DE51C1Q37741285-3212E5CF-3385-4661-AB2F-8FA212C468DAQ37953288-310A6854-A04B-4085-AF7B-A1590CA7640BQ37972089-18326FA0-D2ED-47A8-AD73-58689547E2E5Q38021865-53D99729-0431-44F5-A2D6-9DC785E0A310Q38026830-5516DE5F-FFD4-4A64-B94E-A1EB0C5E814AQ38582520-0637FC6E-9A0A-4641-BA68-BBF3BE3D49B7Q38829987-DEDB88AB-5FF2-4DFD-8D8A-6C22DF04B337Q38859177-FD9AF98F-2856-49DA-9A63-442F9B0D874CQ39044244-E6675EE6-9438-4FCF-9830-F5BBF723C01AQ39834753-82AA21DB-FA6E-4D5B-B10C-C6E1CAE69FA6Q42127267-D0006A20-AC0F-42BF-950D-C0DD6D594735Q47590441-0B0E6EF0-8E78-473E-8729-07F67D842272Q47998495-F7ECC20A-1C15-47CC-8336-A9CD221C25E1Q48106683-529AA7D8-2D1D-4278-8ADF-3EBC93300131Q48340046-7DDEB6A3-27CA-4537-94E6-60C5DF8181D4Q50032095-A87E8175-E3F1-4D73-932D-7EAF9F1F6E79
P2860
Genetic findings in Parkinson's disease and translation into treatment: a leading role for mitochondria?
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Genetic findings in Parkinson' ...... leading role for mitochondria?
@ast
Genetic findings in Parkinson' ...... leading role for mitochondria?
@en
type
label
Genetic findings in Parkinson' ...... leading role for mitochondria?
@ast
Genetic findings in Parkinson' ...... leading role for mitochondria?
@en
prefLabel
Genetic findings in Parkinson' ...... leading role for mitochondria?
@ast
Genetic findings in Parkinson' ...... leading role for mitochondria?
@en
P2093
P2860
P921
P1476
Genetic findings in Parkinson' ...... leading role for mitochondria?
@en
P2093
C van Broeckhoven
V Bogaerts
P2860
P304
P356
10.1111/J.1601-183X.2007.00342.X
P407
P577
2007-08-03T00:00:00Z
2008-03-01T00:00:00Z