Prothrombin deficiency results in embryonic and neonatal lethality in mice.
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Inactivation of the gene for anticoagulant protein C causes lethal perinatal consumptive coagulopathy in miceGenetic and pharmacological modifications of thrombin formation in apolipoprotein e-deficient mice determine atherosclerosis severity and atherothrombosis onset in a neutrophil-dependent mannerStructural basis of Na+ activation mimicry in murine thrombinLaser-induced noninvasive vascular injury models in mice generate platelet- and coagulation-dependent thrombiDefective angiogenesis and fatal embryonic hemorrhage in mice lacking core 1-derived O-glycans.Alternatively spliced tissue factor is not sufficient for embryonic developmentHow the protease thrombin talks to cells.Hemostasis and alterations of the central nervous systemFactor VII deficiency rescues the intrauterine lethality in mice associated with a tissue factor pathway inhibitor deficit.Zebrafish as a model system for the study of hemostasis and thrombosis.Mouse embryogenesis requires the tissue factor extracellular domain but not the cytoplasmic domainAutosomal recessive deficiencies of coagulation factors.Rare coagulation deficiencies.Genetic sequence analysis of inherited bleeding diseases.Thrombin drives tumorigenesis in colitis-associated colon cancerProthrombin structure: unanticipated features and opportunities.The development of inflammatory joint disease is attenuated in mice expressing the anticoagulant prothrombin mutant W215A/E217A.Liver-specific γ-glutamyl carboxylase-deficient mice display bleeding diathesis and short life span.The Fgl2/fibroleukin prothrombinase contributes to immunologically mediated thrombosis in experimental and human viral hepatitisProtease-activated receptors in the cardiovascular system.What is all that thrombin for?Anti-Phosphatidylserine/Prothrombin Antibodies Are Associated with Adverse Pregnancy Outcomes.Modeling Disorders of Blood Coagulation in the Zebrafish.Fatal hemorrhage in mice lacking gamma-glutamyl carboxylase.The rare coagulation disorders--review with guidelines for management from the United Kingdom Haemophilia Centre Doctors' Organisation.Does the genotype predict the phenotype? Evaluations of the hemostatic proteome.Blood coagulation and its regulation by anticoagulant pathways: genetic pathogenesis of bleeding and thrombotic diseases.Mice expressing a mutant form of fibrinogen that cannot support fibrin formation exhibit compromised antimicrobial host defense.Hereditary blood coagulation disorders: management and dental treatment.Tissue factor is required for uterine hemostasis and maintenance of the placental labyrinth during gestation.A guide to murine coagulation factor structure, function, assays, and genetic alterations.Thrombin.The hemostasis system in murine atherosclerosis.Genetic elimination of prothrombin in adult mice is not compatible with survival and results in spontaneous hemorrhagic events in both heart and brain.Reduced thrombin generation increases host susceptibility to group A streptococcal infectionGenetic aspects and research development in haemostasis.Microarray analysis of prothrombin knockdown in zebrafish.Hemifacial microsomia: from gestation to childhood.Historical perspective and future direction of coagulation research.The rare inherited coagulation disorders.
P2860
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P2860
Prothrombin deficiency results in embryonic and neonatal lethality in mice.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Prothrombin deficiency results in embryonic and neonatal lethality in mice.
@ast
Prothrombin deficiency results in embryonic and neonatal lethality in mice.
@en
type
label
Prothrombin deficiency results in embryonic and neonatal lethality in mice.
@ast
Prothrombin deficiency results in embryonic and neonatal lethality in mice.
@en
prefLabel
Prothrombin deficiency results in embryonic and neonatal lethality in mice.
@ast
Prothrombin deficiency results in embryonic and neonatal lethality in mice.
@en
P2093
P2860
P356
P1476
Prothrombin deficiency results in embryonic and neonatal lethality in mice.
@en
P2093
K Holmbäck
M C Burkart
M C Colbert
P2860
P304
P356
10.1073/PNAS.95.13.7597
P407
P577
1998-06-01T00:00:00Z