about
Uracil-DNA glycosylase-DNA substrate and product structures: conformational strain promotes catalytic efficiency by coupled stereoelectronic effectsModification of the human thymine-DNA glycosylase by ubiquitin-like proteins facilitates enzymatic turnoverHuman DNA polymerase beta initiates DNA synthesis during long-patch repair of reduced AP sites in DNAOverexpression of the human HAP1 protein sensitizes cells to the lethal effect of bioreductive drugsSubstitution of Asp-210 in HAP1 (APE/Ref-1) eliminates endonuclease activity but stabilises substrate binding.Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA.Inactivation of the DNA repair genes mutS, mutL or the anti-recombination gene mutS2 leads to activation of vitamin B1 biosynthesis genes.DNA damage in plant herbarium tissueAfrican swine fever virus AP endonuclease is a redox-sensitive enzyme that repairs alkylating and oxidative damage to DNA.Mammalian base excision repair: the forgotten archangelDNA damage by peroxynitrite characterized with DNA repair enzymes.Enzymic removal of 5-methylcytosine from DNA by a human DNA-glycosylase.Design and activity of AP endonuclease-1 inhibitors.Discontinuous or semi-discontinuous DNA replication in Escherichia coli?Endonuclease-sensitive DNA modifications induced by acetone and acetophenone as photosensitizers.Irradiation of DNA with 193 nm light yields formamidopyrimidine-DNA glycosylase(Fpg) protein-sensitive lesions.DNA excision repair in mammalian cell extracts.Base excision repair of oxidative DNA damage and association with cancer and agingComparative analysis of editosome proteins in trypanosomatidsMy journey to DNA repair.Photolysis of N-hydroxpyridinethiones: a new source of hydroxyl radicals for the direct damage of cell-free and cellular DNA.Analysis of the impact of a uracil DNA glycosylase attenuated in AP-DNA binding in maintenance of the genomic integrity in Escherichia coli.A role for the human DNA repair enzyme HAP1 in cellular protection against DNA damaging agents and hypoxic stress.Recognition of oxidized abasic sites by repair endonucleases.African swine fever virus protein pE296R is a DNA repair apurinic/apyrimidinic endonuclease required for virus growth in swine macrophages.Uracil-DNA glycosylase affects mismatch repair efficiency in transformation and bisulfite-induced mutagenesis in Streptococcus pneumoniae.Induction of chromosomal instability by chronic oxidative stressBloom helicase is involved in DNA surveillance in early S phase in vertebrate cells.Expression levels of the DNA repair enzyme HAP1 do not correlate with the radiosensitivities of human or HAP1-transfected rat cell lines.Role of the HAP1 protein in repair of oxidative DNA damage and regulation of transcription factors.Spectrum of spontaneous HPRT- mutations in TK6 human lymphoblasts.Early decrease of apurinic/apyrimidinic endonuclease expression after transient focal cerebral ischemia in mice.DNA oxidation products determined with repair endonucleases in mammalian cells: types, basal levels and influence of cell proliferation.The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sitesEscherichia coli apurinic-apyrimidinic endonucleases enhance the turnover of the adenine glycosylase MutY with G:A substrates.Base-excision repair and beyond --A short summary attributed to scientific achievements of Tomas Lindahl, Nobel Prize Laureate in Chemistry 2015.Ubiquitous presence in mammalian cells of enzymatic activity specifically cleaving 8-hydroxyguanine-containing DNA.Spectrum of spontaneous missense mutations causing cyclic AMP-resistance phenotypes in cultured S49 mouse lymphoma cells differs markedly from those of mutations induced by alkylating mutagens.
P2860
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P2860
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
@zh
1990年论文
@zh-cn
name
Repair of intrinsic DNA lesions.
@ast
Repair of intrinsic DNA lesions.
@en
type
label
Repair of intrinsic DNA lesions.
@ast
Repair of intrinsic DNA lesions.
@en
prefLabel
Repair of intrinsic DNA lesions.
@ast
Repair of intrinsic DNA lesions.
@en
P1433
P1476
Repair of intrinsic DNA lesions.
@en
P304
P356
10.1016/0165-1110(90)90022-4
P407
P577
1990-05-01T00:00:00Z