Interleukin-3 signals through multiple isoforms of Stat5.
about
Antiapoptotic activity of Stat5 required during terminal stages of myeloid differentiationThe SH2 domains of Stat1 and Stat2 mediate multiple interactions in the transduction of IFN-alpha signalsBiological effects of c-Mer receptor tyrosine kinase in hematopoietic cells depend on the Grb2 binding site in the receptor and activation of NF-kappaB.Mouse oncostatin M: an immediate early gene induced by multiple cytokines through the JAK-STAT5 pathwayA Stat3-interacting protein (StIP1) regulates cytokine signal transductionHuman interleukin-3 (IL-3) induces disulfide-linked IL-3 receptor alpha- and beta-chain heterodimerization, which is required for receptor activation but not high-affinity bindingSTAT5 in hematopoietic stem cell biology and transplantationStat5b is essential for natural killer cell-mediated proliferation and cytolytic activityDNA binding site selection of dimeric and tetrameric Stat5 proteins reveals a large repertoire of divergent tetrameric Stat5a binding sitesCharacterization of Stat5a and Stat5b homodimers and heterodimers and their association with the glucocortiocoid receptor in mammary cellsSignal transducer and activator of transcription (STAT)5 activation by BCR/ABL is dependent on intact Src homology (SH)3 and SH2 domains of BCR/ABL and is required for leukemogenesisAbrogation of interleukin-3 dependence of myeloid cells by the v-src oncogene requires SH2 and SH3 domains which specify activation of STATsM-CSF and GM-CSF regulation of STAT5 activation and DNA binding in myeloid cell differentiation is disrupted in nonobese diabetic miceDistinct gene-expression profiles characterize mammary tumors developed in transgenic mice expressing constitutively active and C-terminally truncated variants of STAT5.The transcriptional STAT3 is a potential target, whereas transcriptional STAT5A/5B/6 are new biomarkers for prognosis in human breast carcinoma.Transcriptional regulation of the cyclin D1 promoter by STAT5: its involvement in cytokine-dependent growth of hematopoietic cells.Cooperative transcriptional activity of Jun and Stat3 beta, a short form of Stat3Cloning and expression of Stat5 and an additional homologue (Stat5b) involved in prolactin signal transduction in mouse mammary tissue.The antiapoptotic gene mcl-1 is up-regulated by the phosphatidylinositol 3-kinase/Akt signaling pathway through a transcription factor complex containing CREBCoupling of osteopontin and its cell surface receptor CD44 to the cell survival response elicited by interleukin-3 or granulocyte-macrophage colony-stimulating factor.Bcl3 prevents acute inflammatory lung injury in mice by restraining emergency granulopoiesis.Mimicry of erythropoietin by a nonpeptide moleculeIdentification of tyrosine residues within the intracellular domain of the erythropoietin receptor crucial for STAT5 activationErythropoietin-induced erythroid differentiation of the human erythroleukemia cell line TF-1 correlates with impaired STAT5 activationSignal transducer and activator of transcription (STAT) signalling and T-cell lymphomas.A proliferation switch for genetically modified cells.Essential role of signal transducer and activator of transcription (Stat)5a but not Stat5b for Flt3-dependent signaling.Erythropoietin induces activation of Stat5 through association with specific tyrosines on the receptor that are not required for a mitogenic response.The murine DUB-1 gene is specifically induced by the betac subunit of interleukin-3 receptor.Deletion of the carboxyl-terminal transactivation domain of MGF-Stat5 results in sustained DNA binding and a dominant negative phenotype.Naturally occurring dominant negative variants of Stat5.Mutation in the Jak kinase JH2 domain hyperactivates Drosophila and mammalian Jak-Stat pathways.Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expressionOligomerization and scaffolding functions of the erythropoietin receptor cytoplasmic tail.Interpretation of cytokine signaling through the transcription factors STAT5A and STAT5BCytokine signaling through Stat3 activates integrins, promotes adhesion, and induces growth arrest in the myeloid cell line 32D.Genomic dissection of the cytokine-controlled STAT5 signaling network in liverHuman immunodeficiency virus type 1 infection inhibits granulocyte-macrophage colony-stimulating factor-induced activation of STAT5A in human monocyte-derived macrophages.Inteferons pen the JAK-STAT pathway.Inhibition of cytokines and JAK-STAT activation by distinct signaling pathways.
P2860
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P2860
Interleukin-3 signals through multiple isoforms of Stat5.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Interleukin-3 signals through multiple isoforms of Stat5.
@ast
Interleukin-3 signals through multiple isoforms of Stat5.
@en
type
label
Interleukin-3 signals through multiple isoforms of Stat5.
@ast
Interleukin-3 signals through multiple isoforms of Stat5.
@en
prefLabel
Interleukin-3 signals through multiple isoforms of Stat5.
@ast
Interleukin-3 signals through multiple isoforms of Stat5.
@en
P2093
P2860
P1433
P1476
Interleukin-3 signals through multiple isoforms of Stat5
@en
P2093
B L Kreider
C Schindler
H Erdjument-Bromage
P2860
P304
P356
10.1002/J.1460-2075.1995.TB07126.X
P407
P577
1995-04-01T00:00:00Z