A dileucine motif in the C terminus of the beta2-adrenergic receptor is involved in receptor internalization.
about
Seven non-contiguous intracellular residues of the lutropin/choriogonadotropin receptor dictate the rate of agonist-induced internalization and its sensitivity to non-visual arrestinsIdentification of a motif in the carboxyl terminus of CXCR2 that is involved in adaptin 2 binding and receptor internalizationThe structural basis of arrestin-mediated regulation of G-protein-coupled receptorsIdentification of the human receptor activity-modifying protein 1 domains responsible for agonist binding specificityA dopamine D2 receptor mutant capable of G protein-mediated signaling but deficient in arrestin bindingA modular, fully integrated ultra-high-throughput screening system based on confocal fluorescence analysis techniques.G protein-coupled receptor sorting to endosomes and lysosomes.Internalization and sequestration of the human prostacyclin receptor.The NH(2)-terminus of norepinephrine transporter contains a basolateral localization signal for epithelial cells.C-terminal di-leucine motif of dopamine D₁ receptor plays an important role in its plasma membrane trafficking.Mutating the dileucine motif of the human beta(2)-adrenoceptor reduces the high initial rate of receptor phosphorylation by GRK without affecting postendocytic sorting.Modulation of cellular signaling by herpesvirus-encoded G protein-coupled receptors.Functions of DPLIY motif and helix 8 of human melanocortin-3 receptor.Hierarchical phosphorylation of delta-opioid receptor regulates agonist-induced receptor desensitization and internalizationThe G protein-coupled receptors: pharmacogenetics and disease.Beta 2-adrenergic receptor activation enhances neurogenesis in Alzheimer's disease mice.H2, the minor subunit of the human asialoglycoprotein receptor, trafficks intracellularly and forms homo-oligomers, but does not bind asialo-orosomucoid.Internalization-defective mutants of somatostatin receptor subtype 2 exert normal signaling functions in hematopoietic cells.Regulation of β2-adrenergic receptor maturation and anterograde trafficking by an interaction with Rab geranylgeranyltransferase: modulation of Rab geranylgeranylation by the receptorCK2 phosphorylation of an acidic Ser/Thr di-isoleucine motif in the Na+/H+ exchanger NHE5 isoform promotes association with beta-arrestin2 and endocytosis.Role of the G protein-coupled receptor kinase site serine cluster in beta2-adrenergic receptor internalization, desensitization, and beta-arrestin translocation.Structural determinants regulating expression of the high affinity leukotriene B4 receptor: involvement of dileucine motifs and alpha-helix VIII.Internalization determinants of the parathyroid hormone receptor differentially regulate beta-arrestin/receptor association.Receptor-ligand interactions studied with homogeneous fluorescence-based assays suitable for miniaturized screening.Growth hormone receptor ubiquitination coincides with recruitment to clathrin-coated membrane domains.Multiple distant amino acid residues present in the serpentine region of the follitropin receptor modulate the rate of agonist-induced internalization.Distinct function of the cytoplasmic tail in human D1-like receptor ligand binding and coupling.Role of the carboxyl-terminal region, di-leucine motif and cysteine residues in signalling and internalization of vasopressin V1a receptor.The rate of internalization of the gonadotropin receptors is greatly affected by the origin of the extracellular domain.Role of two dileucine-like motifs in insulin receptor anchoring to microvilli.The intracellular trafficking of opioid receptors directed by carboxyl tail and a di-leucine motif in Neuro2A cells.Leucine-based receptor sorting motifs are dependent on the spacing relative to the plasma membrane.Di-leucine-mediated internalization of ligand by a truncated growth hormone receptor is independent of the ubiquitin conjugation system.Interactions between the Hepatitis C Virus Nonstructural 2 Protein and Host Adaptor Proteins 1 and 4 Orchestrate Virus Release.
P2860
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P2860
A dileucine motif in the C terminus of the beta2-adrenergic receptor is involved in receptor internalization.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
A dileucine motif in the C ter ...... d in receptor internalization.
@en
type
label
A dileucine motif in the C ter ...... d in receptor internalization.
@en
prefLabel
A dileucine motif in the C ter ...... d in receptor internalization.
@en
P2093
P2860
P356
P1476
A dileucine motif in the C ter ...... d in receptor internalization.
@en
P2093
P2860
P304
12285-12290
P356
10.1073/PNAS.94.23.12285
P407
P577
1997-11-01T00:00:00Z