Total synthesis of (-)- and ent-(+)-vindoline and related alkaloids. - Wikidata - awgldk - TriplyDB

Total synthesis of (-)- and ent-(+)-vindoline and related alkaloids.

Total synthesis of (-)- and ent-(+)-vindoline and related alkaloids.

http://www.wikidata.org/entity/Q36865773

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Total synthesis of vinblastine, related natural products, and key analogues and development of inspired methodology suitable for the systematic study of their structure-function properties Total synthesis of (+)-fendleridine (aspidoalbidine) and (+)-1-acetylaspidoalbidine Total synthesis of lycogarubin C and lycogalic acid.Asymmetric total synthesis of vindoline Total synthesis and evaluation of a key series of C5-substituted vinblastine derivatives Asymmetric total synthesis of vindorosine, vindoline, and key vinblastine analogues Catharanthine C16 substituent effects on the biomimetic coupling with vindoline: preparation and evaluation of a key series of vinblastine analogues.Cycloadditions of noncomplementary substituted 1,2,3-triazines.Scope of the inverse electron demand Diels-Alder reactions of 1,2,3-triazine.Inverse electron demand Diels-Alder reactions of 1,2,3-triazines: pronounced substituent effects on reactivity and cycloaddition scope 10'-Fluorovinblastine and 10'-Fluorovincristine: Synthesis of a Key Series of Modified Vinca Alkaloids.Total synthesis of (-)-kopsinine and ent-(+)-kopsinine Iron(III)/NaBH4-mediated additions to unactivated alkenes: synthesis of novel 20'-vinblastine analogues Divergent total syntheses of (-)-aspidospermine and (+)-spegazzinine.Cycloadditions of 1,2,3-Triazines Bearing C5-Electron Donating Substituents: Robust Pyrimidine Synthesis Total Synthesis of (-)-Vindoline and (+)-4-epi-Vindoline Based on a 1,3,4-Oxadiazole Tandem Intramolecular [4 + 2]/[3 + 2] Cycloaddition Cascade Initiated by an Allene Dienophile.Total synthesis and evaluation of vinblastine analogues containing systematic deep-seated modifications in the vindoline subunit ring system: core redesign.Tandem Intramolecular Diels-Alder/1,3-Dipolar Cycloaddition Cascade of 1,3,4-Oxadiazoles: Initial Scope and Applications.A remarkable series of vinblastine analogues displaying enhanced activity and an unprecedented tubulin binding steric tolerance: C20' urea derivatives.Total synthesis of kopsinine.Direct coupling of catharanthine and vindoline to provide vinblastine: total synthesis of (+)- and ent-(-)-vinblastine Synthesis of spirocyclic indolines by interruption of the Bischler-Napieralski reaction.Potent Vinblastine C20' Ureas Displaying Additionally Improved Activity Against a Vinblastine-Resistant Cancer Cell Line.Total synthesis of vinblastine, vincristine, related natural products, and key structural analogues Transannular Diels-Alder/1,3-dipolar cycloaddition cascade of 1,3,4-oxadiazoles: total synthesis of a unique set of vinblastine analogues.Total synthesis of a key series of vinblastines modified at C4 that define the importance and surprising trends in activity.Total syntheses of (-)-kopsifoline D and (-)-deoxoapodine: divergent total synthesis via late-stage key strategic bond formation.Gas extrusion in natural products total synthesis.Vinblastine 20' Amides: Synthetic Analogues That Maintain or Improve Potency and Simultaneously Overcome Pgp-Derived Efflux and Resistance.Palladium catalysed meta-C-H functionalization reactions.Total synthesis and biological evaluation of jerantinine E.Inverse-Electron-Demand Diels-Alder Reactions: Principles and Applications.Formation and Trapping of Azafulvene Intermediates Derived from Manganese-Mediated Oxidative Malonate Coupling.Base mediated deprotection strategies for trifluoroethyl (TFE) ethers, a new alcohol protecting group.Evolution of an oxidative dearomatization enabled total synthesis of vinigrol A concise and versatile double-cyclization strategy for the highly stereoselective synthesis and arylative dimerization of Aspidosperma alkaloids.Total synthesis of punctaporonin C by a regio- and stereoselective [2+2]-photocycloaddition.The Difference a Single Atom Can Make: Synthesis and Design at the Chemistry-Biology Interface.Direct Synthesis of β-Aminoenals through Reaction of 1,2,3-Triazine with Secondary Amines.Total Synthesis of (-)-Vindorosine.

P2860

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P2860

Total synthesis of (-)- and ent-(+)-vindoline and related alkaloids.

http://www.wikidata.org/entity/Q36865773

description

2006 nî lūn-bûn

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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2006年论文

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2006年论文

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name

Total synthesis of (-)- and ent-(+)-vindoline and related alkaloids.

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type

label

Total synthesis of (-)- and ent-(+)-vindoline and related alkaloids.

@en

prefLabel

Total synthesis of (-)- and ent-(+)-vindoline and related alkaloids.

@en

P1433

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P1433

Journal of the American Chemical Society

P1476

Total synthesis of (-)- and ent-(+)-vindoline and related alkaloids.

@en

P2093

Dale L Boger

http://www.w3.org/2001/XMLSchema#string

Gregory I Elliott

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Hayato Ishikawa

http://www.w3.org/2001/XMLSchema#string

Juraj Velcicky

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Younggi Choi

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P2860

Purification, characterization, and kinetic analysis of a 2-oxoglutarate-dependent dioxygenase involved in vindoline biosynthesis from Catharanthus roseus

Total synthesis of (+)-aspidospermidine: a new strategy for the enantiospecific synthesis of aspidosperma alkaloids.

Structures of leurocristine (vincristine) and vincaleukoblastine. X-ray analysis of leurocristine methiodide.

Revisiting a classic approach to the Aspidosperma alkaloids: an intramolecular Schmidt reaction mediated synthesis of (+)-aspidospermidine.

Total synthesis of natural (+)- [corrected] and ent-(-)-4-desacetoxy-6,7-dihydrovindorosine [corrected] and natural and ent-minovine: oxadiazole tandem intramolecular Diels-Alder/1,3-dipolar cycloaddition reaction.

Total synthesis of (-)- and ent-(+)-vindoline.

Intramolecular diels-alder/1,3-dipolar cycloaddition cascade of 1,3,4-oxadiazoles.

Stereocontrolled total synthesis of (+)-vincristine.

Stereocontrolled total synthesis of (+)-vinblastine.

Catalytic enantioselective synthesis of alpha-aminooxy and alpha-hydroxy ketone using nitrosobenzene.

P304

10596-10612

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scholarly article

P356

10.1021/JA061256T

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P433

32

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P478

128

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P577

2006-08-01T00:00:00Z

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6892538

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16895428

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2531198

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