Transcriptional trans-activation by the human papillomavirus type 16 E2 gene product.
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Ski interacts with the evolutionarily conserved SNW domain of SkipCornifin, a cross-linked envelope precursor in keratinocytes that is down-regulated by retinoidsHuman papillomavirus induced transformation in cervical and head and neck cancersAdeno-associated virus type 2 rep protein inhibits human papillomavirus type 16 E2 recruitment of the transcriptional coactivator p300.Antisense Myc sequences induce differentiation of F9 cells.Transactivation by the E2 protein of oncogenic human papillomavirus type 31 is not essential for early and late viral functions.E2 polypeptides encoded by bovine papillomavirus type 1 form dimers through the common carboxyl-terminal domain: transactivation is mediated by the conserved amino-terminal domain.A synthetic peptide defines a serologic IgA response to a human papillomavirus-encoded nuclear antigen expressed in virus-carrying cervical neoplasia.HPV-16 E2 gene disruption and sequence variation in CIN 3 lesions and invasive squamous cell carcinomas of the cervix: relation to numerical chromosome abnormalities.The upstream regulatory region of the human papilloma virus-16 contains an E2 protein-independent enhancer which is specific for cervical carcinoma cells and regulated by glucocorticoid hormones.Transcriptional regulation of the human papillomavirus-16 E6-E7 promoter by a keratinocyte-dependent enhancer, and by viral E2 trans-activator and repressor gene products: implications for cervical carcinogenesis.The bovine papillomavirus constitutive enhancer is essential for viral transformation, DNA replication, and the maintenance of latencyStructure-function analysis of the human papillomavirus type 16 E7 oncoprotein.Separation of the transcriptional activation and replication functions of the bovine papillomavirus-1 E2 protein.A transactivator function of cottontail rabbit papillomavirus e2 is essential for tumor induction in rabbits.During negative regulation of the human papillomavirus-16 E6 promoter, the viral E2 protein can displace Sp1 from a proximal promoter element.Brd4 is required for e2-mediated transcriptional activation but not genome partitioning of all papillomaviruses.Identification and analysis of papillomavirus E2 protein binding sites in the human genome.Transcription of the transforming genes of the oncogenic human papillomavirus-16 is stimulated by tumor promotors through AP1 binding sites.Expression of the L2 and E7 genes of the human papillomavirus type 16 in female genital dysplasiasEnhanced transcriptional activation by E2 proteins from the oncogenic human papillomavirusesMechanisms of human papillomavirus-induced oncogenesis.The specific DNA recognition sequence of the bovine papillomavirus E2 protein is an E2-dependent enhancerThe carboxy-terminal domain shared by the bovine papillomavirus E2 transactivator and repressor proteins contains a specific DNA binding activity.Sequence-specific and general transcriptional activation by the bovine papillomavirus-1 E2 trans-activator require an N-terminal amphipathic helix-containing E2 domain.Structural and mutational analysis of E2 trans-activating proteins of papillomaviruses reveals three distinct functional domains.Expression and amplification in transgenic mice of a polyoma virus mutant regulatory region.Nuclear proto-oncogene products transactivate the human papillomavirus type 16 promoter.The human papillomavirus type 16 E2 transcription factor binds with low cooperativity to two flanking sites and represses the E6 promoter through displacement of Sp1 and TFIID.trans activation by the full-length E2 proteins of human papillomavirus type 16 and bovine papillomavirus type 1 in vitro and in vivo: cooperation with activation domains of cellular transcription factors.Presence of catenated human papillomavirus type 16 episomes in a cervical carcinoma cell line.Numerous nuclear proteins bind the long control region of human papillomavirus type 16: a subset of 6 of 23 DNase I-protected segments coincides with the location of the cell-type-specific enhancer.Identification of human papillomavirus type 18 transforming genes in immortalized and primary cellsThe E6/E7 promoter of human papillomavirus type 16 is activated in the absence of E2 proteins by a sequence-aberrant Sp1 distal element.Mutational analysis of cis elements involved in E2 modulation of human papillomavirus type 16 P97 and type 18 P105 promoters.Identification of the human papillomavirus E2 protein in genital tract tissues.Analysis of trans activation by human papillomavirus type 16 E7 and adenovirus 12S E1A suggests a common mechanism.Identification of a novel constitutive enhancer element and an associated binding protein: implications for human papillomavirus type 11 enhancer regulationGenetic assignment of multiple E2 gene products in bovine papillomavirus-transformed cellsProgesterone and glucocorticoid response elements occur in the long control regions of several human papillomaviruses involved in anogenital neoplasia
P2860
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P2860
Transcriptional trans-activation by the human papillomavirus type 16 E2 gene product.
description
1987 nî lūn-bûn
@nan
1987年の論文
@ja
1987年論文
@yue
1987年論文
@zh-hant
1987年論文
@zh-hk
1987年論文
@zh-mo
1987年論文
@zh-tw
1987年论文
@wuu
1987年论文
@zh
1987年论文
@zh-cn
name
Transcriptional trans-activation by the human papillomavirus type 16 E2 gene product.
@en
type
label
Transcriptional trans-activation by the human papillomavirus type 16 E2 gene product.
@en
prefLabel
Transcriptional trans-activation by the human papillomavirus type 16 E2 gene product.
@en
P2860
P1433
P1476
Transcriptional trans-activation by the human papillomavirus type 16 E2 gene product.
@en
P2093
P M Howley
W C Phelps
P2860
P304
P407
P577
1987-05-01T00:00:00Z