p185, a product of the neu proto-oncogene, is a receptorlike protein associated with tyrosine kinase activity
about
The HER2 Receptor in Breast Cancer: Pathophysiology, Clinical Use, and New Advances in TherapyOncogenic forms of the neu/HER2 tyrosine kinase are permanently coupled to phospholipase C gammaNeural expression and chromosomal mapping of Neu differentiation factor to 8p12-p21Activated neu oncogene sequences in primary tumors of the peripheral nervous system induced in rats by transplacental exposure to ethylnitrosoureaIdentification of the protein encoded by the human diffuse B-cell lymphoma (dbl) oncogenec-erbB2 and topoisomerase IIalpha protein expression independently predict poor survival in primary human breast cancer: a retrospective studyThe Role of Forkhead Box Protein M1 in Breast Cancer Progression and Resistance to TherapyInsulin-like growth factor and epidermal growth factor signaling in breast cancer cell growth: focus on endocrine resistant diseaseAt the crossroads: EGFR and PTHrP signaling in cancer-mediated diseases of boneThe HER-2/neu receptor tyrosine kinase gene encodes a secreted autoinhibitorMMTV mouse models and the diagnostic values of MMTV-like sequences in human breast cancerCorrelation of the structure of the transmembrane domain of the neu oncogene-encoded p185 protein with its functionHeregulin regulates cytoskeletal reorganization and cell migration through the p21-activated kinase-1 via phosphatidylinositol-3 kinaseAnalysis of Her2/neu membrane protein clusters in different types of breast cancer cells using localization microscopyConversion of a phosphoseryl/threonyl phosphatase into a phosphotyrosyl phosphataseErbB4 signaling in the mammary gland is required for lobuloalveolar development and Stat5 activation during lactationActivation of ErbB4 by the bifunctional epidermal growth factor family hormone epiregulin is regulated by ErbB2Constitutive activation of fibroblast growth factor receptor 3 by the transmembrane domain point mutation found in achondroplasiaClathrin-independent endocytosis of ErbB2 in geldanamycin-treated human breast cancer cells.Spk1, a new kinase from Saccharomyces cerevisiae, phosphorylates proteins on serine, threonine, and tyrosine.Tight correlation between expression of the Forkhead transcription factor FOXM1 and HER2 in human breast cancer.Production and characterisation of monoclonal antibodies against RAI3 and its expression in human breast cancer.A chimeric EGF-R-neu proto-oncogene allows EGF to regulate neu tyrosine kinase and cell transformation.Transcriptional repression of the neu protooncogene by the adenovirus 5 E1A gene products.Phosphorylation process induced by epidermal growth factor alters the oncogenic and cellular neu (NGL) gene products.Increased tyrosine kinase activity associated with the protein encoded by the activated neu oncogene.neu protooncogene fused to an immunoglobulin heavy chain gene requires immunoglobulin light chain for cell surface expression and oncogenic transformation.The epidermal growth factor receptor and the product of the neu protooncogene are members of a receptor tyrosine phosphorylation cascade.Activation of Neu (ErbB-2) mediated by disulfide bond-induced dimerization reveals a receptor tyrosine kinase dimer interface.Role of HER2 gene overexpression in breast carcinoma.Amplification of the proto-neu oncogene facilitates oncogenic activation by a single point mutation.Experimental approaches to hypothetical hormones: detection of a candidate ligand of the neu protooncogene.Overexpression of the EGF receptor-related proto-oncogene erbB-2 in human mammary tumor cell lines by different molecular mechanismsOverexpression of ErbB2 in cancer and ErbB2-targeting strategies.A subdomain in the transmembrane domain is necessary for p185neu* activation.Transgenic mouse models of human breast cancer.Comparing fluorescence in situ hybridization and chromogenic in situ hybridization methods to determine the HER2/neu status in primary breast carcinoma using tissue microarray.Increasing CD44+/CD24(-) tumor stem cells, and upregulation of COX-2 and HDAC6, as major functions of HER2 in breast tumorigenesisIncreased expression of the putative growth factor receptor p185HER2 causes transformation and tumorigenesis of NIH 3T3 cells.EGFs and ERBBs--brief history and prospects
P2860
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P2860
p185, a product of the neu proto-oncogene, is a receptorlike protein associated with tyrosine kinase activity
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
1986年论文
@zh
1986年论文
@zh-cn
name
p185, a product of the neu pro ...... with tyrosine kinase activity
@en
type
label
p185, a product of the neu pro ...... with tyrosine kinase activity
@en
prefLabel
p185, a product of the neu pro ...... with tyrosine kinase activity
@en
P2093
P2860
P356
P1476
p185, a product of the neu pro ...... with tyrosine kinase activity
@en
P2093
P A Heffernan
R A Weinberg
P2860
P304
P356
10.1128/MCB.6.5.1729
P407
P577
1986-05-01T00:00:00Z