Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs. - Wikidata - awgldk - TriplyDB

Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs.

Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs.

http://www.wikidata.org/entity/Q36944556

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Generation of knockout rabbits using transcription activator-like effector nucleases Rab11b regulates the apical recycling of the cystic fibrosis transmembrane conductance regulator in polarized intestinal epithelial cells A decade of Burkholderia cenocepacia virulence determinant research Precision editing of large animal genomes Identification of IFRD1 as a modifier gene for cystic fibrosis lung disease Developmental biology: Transgenic primate offspring Epithelial Anion Transport as Modulator of Chemokine Signaling Animal Models of Cystic Fibrosis Pathology: Phenotypic Parallels and Divergences Engineering large animal models of human disease Genetics in non-genetic model systems NETs and CF Lung Disease: Current Status and Future Prospects Thyroid iodide efflux: a team effort?Gene therapy: light is finally in the tunnel Cystic fibrosis therapeutics: the road ahead Current progress of genetically engineered pig models for biomedical research Loss of cftr function leads to pancreatic destruction in larval zebrafish.Characterization of defects in ion transport and tissue development in cystic fibrosis transmembrane conductance regulator (CFTR)-knockout rats Method for quantitative study of airway functional microanatomy using micro-optical coherence tomography Germline transgenic pigs by Sleeping Beauty transposition in porcine zygotes and targeted integration in the pig genome Porcine model of hemophilia A Classical swine fever virus replicated poorly in cells from MxA transgenic pigs Origins of cystic fibrosis lung disease Precision Genomic Medicine in Cystic Fibrosis Airway Gland Structure and Function Somatic cell nuclear transfer: origins, the present position and future opportunities Genetically manipulated mouse models of lung disease: potential and pitfalls Computed Tomography and Magnetic Resonance Imaging for Longitudinal Characterization of Lung Structure Changes in a Yucatan Miniature Pig Silicosis Model The primary folding defect and rescue of ΔF508 CFTR emerge during translation of the mutant domain A bovine model of respiratory Chlamydia psittaci infection: challenge dose titration CFTR delivery to 25% of surface epithelial cells restores normal rates of mucus transport to human cystic fibrosis airway epithelium Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases Barriers to inhaled gene therapy of obstructive lung diseases: A review Integrative analysis of differentially expressed microRNAs of pulmonary alveolar macrophages from piglets during H1N1 swine influenza A virus infection Impact of the F508del mutation on ovine CFTR, a Cl- channel with enhanced conductance and ATP-dependent gating.Swine influenza H1N1 virus induces acute inflammatory immune responses in pig lungs: a potential animal model for human H1N1 influenza virus.Generation of antibody- and B cell-deficient pigs by targeted disruption of the J-region gene segment of the heavy chain locus.Strategies for whole lung tissue engineering.Hsp 70/Hsp 90 organizing protein as a nitrosylation target in cystic fibrosis therapy.CFTR-deficient pigs display peripheral nervous system defects at birth.Cftr controls lumen expansion and function of Kupffer's vesicle in zebrafish.

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P2860

Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs.

http://www.wikidata.org/entity/Q36944556

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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2008年论文

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2008年论文

@zh-cn

name

Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs.

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Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs.

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Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs.

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Amanda C Kabel

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August Rieke

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Christine L Wohlford-Lenane

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Christopher S Rogers

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Clifton N Murphy

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David Wax

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Greg J Davis

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Kim A Brogden

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Kristin Whitworth

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Mark P Rogan

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P2860

Relative contribution of genetic and nongenetic modifiers to intestinal obstruction in cystic fibrosis.

Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA

Cystic fibrosis

Production of CFTR-null and CFTR-DeltaF508 heterozygous pigs by adeno-associated virus-mediated gene targeting and somatic cell nuclear transfer

Pathophysiology of gene-targeted mouse models for cystic fibrosis

Standardized procedure for measurement of nasal potential difference: an outcome measure in multicenter cystic fibrosis clinical trials.

Discovery of glycine hydrazide pore-occluding CFTR inhibitors: mechanism, structure-activity analysis, and in vivo efficacy.

Pathology of cystic fibrosis review of the literature and comparison with 146 autopsied cases.

Localization of cystic fibrosis transmembrane conductance regulator in chloride secretory epithelia

Regulation of transepithelial ion transport and intracellular calcium by extracellular ATP in human normal and cystic fibrosis airway epithelium.

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321

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David Meyerholz

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Timothy D Starner

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2008-09-01T00:00:00Z

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23281809

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18818360

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cystic fibrosis

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