Caudo-rostral brain spreading of α-synuclein through vagal connections
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Toward precision medicine in Parkinson's diseaseThe complex relationships between microglia, alpha-synuclein, and LRRK2 in Parkinson's diseaseAlpha-synuclein biology in Lewy body diseasesPropagation of alpha-synuclein pathology: hypotheses, discoveries, and yet unresolved questions from experimental and human brain studies.The bowel and beyond: the enteric nervous system in neurological disordersAlpha-synuclein spreading in Parkinson's diseaseIntrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degenerationESCRT-mediated uptake and degradation of brain-targeted α-synuclein single chain antibody attenuates neuronal degeneration in vivo.Neuroinvasion of α-Synuclein Prionoids after Intraperitoneal and Intraglossal Inoculation.The role of extracellular vesicles in the progression of neurodegenerative disease and cancerPathological alpha-synuclein propagates through neural networksPathogenesis of Parkinson disease--the gut-brain axis and environmental factors.Transfer of human α-synuclein from the olfactory bulb to interconnected brain regions in mice.Neuron-to-neuron α-synuclein propagation in vivo is independent of neuronal injuryDirect evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats.Gut microbiota are related to Parkinson's disease and clinical phenotype.Prion-like propagation of human brain-derived alpha-synuclein in transgenic mice expressing human wild-type alpha-synuclein.Induction of α-synuclein aggregate formation by CSF exosomes from patients with Parkinson's disease and dementia with Lewy bodies.Anti-α-synuclein immunotherapy reduces α-synuclein propagation in the axon and degeneration in a combined viral vector and transgenic model of synucleinopathy.Neuropathological Staging of Brain Pathology in Sporadic Parkinson's disease: Separating the Wheat from the Chaff.Amyotrophic lateral sclerosis--a model of corticofugal axonal spread.Cell-to-cell transmission of pathogenic proteins in neurodegenerative diseases.Protein Transmission, Seeding and Degradation: Key Steps for α-Synuclein Prion-Like PropagationPrions and Protein Assemblies that Convey Biological Information in Health and Disease.The prion hypothesis of Parkinson's disease.Neuropathology of α-synuclein propagation and braak hypothesis.Alpha-synuclein propagation: New insights from animal models.Failing as doorman and disc jockey at the same time: Amygdalar dysfunction in Parkinson's disease.Review: Sporadic Parkinson's disease: development and distribution of α-synuclein pathology.Review: Spreading the word: precise animal models and validated methods are vital when evaluating prion-like behaviour of alpha-synuclein.Cellular internalization of alpha-synuclein aggregates by cell surface heparan sulfate depends on aggregate conformation and cell typeSynaptic failure and α-synuclein.Oral biomarkers in exercise-induced neuroplasticity in Parkinson's disease.How strong is the evidence that Parkinson's disease is a prion disorder?Potential Pathways of Abnormal Tau and α-Synuclein Dissemination in Sporadic Alzheimer's and Parkinson's Diseases.An order in Lewy body disorders: Retrograde degeneration in hyperbranching axons as a fundamental structural template accounting for focal/multifocal Lewy body disease.Brain-to-stomach transfer of α-synuclein via vagal preganglionic projections.Selective neuronal vulnerability in Parkinson disease.Targeting Microglial Activation States as a Therapeutic Avenue in Parkinson's Disease.Animal models of α-synucleinopathy for Parkinson disease drug development.
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Caudo-rostral brain spreading of α-synuclein through vagal connections
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 23 May 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Caudo-rostral brain spreading of α-synuclein through vagal connections
@en
Caudo-rostral brain spreading of α-synuclein through vagal connections.
@nl
type
label
Caudo-rostral brain spreading of α-synuclein through vagal connections
@en
Caudo-rostral brain spreading of α-synuclein through vagal connections.
@nl
prefLabel
Caudo-rostral brain spreading of α-synuclein through vagal connections
@en
Caudo-rostral brain spreading of α-synuclein through vagal connections.
@nl
P2093
P2860
P356
P1476
Caudo-rostral brain spreading of α-synuclein through vagal connections
@en
P2093
Ayse Ulusoy
Bettina Winzen-Reichert
Blanca I Pérez-Revuelta
Donato A Di Monte
Michael Helwig
Raffaella Rusconi
Ruth E Musgrove
P2860
P304
P356
10.1002/EMMM.201302475
P577
2013-05-23T00:00:00Z