Bmi-1 regulates the Ink4a/Arf locus to control pancreatic beta-cell proliferation.
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Induction of human beta-cell proliferation and engraftment using a single G1/S regulatory molecule, cdk6The role of epigenetics in the pathology of diabetic complicationsRhoB loss prevents streptozotocin-induced diabetes and ameliorates diabetic complications in miceEpigenetics: a molecular link between environmental factors and type 2 diabetesChanges in Regenerative Capacity through LifespanEpigenetic Regulation of Islet Development and RegenerationEpithelial-mesenchymal transition and cancer stemness: the Twist1-Bmi1 connectionAging-Induced Stem Cell Mutations as Drivers for Disease and CancerBmi-1 promotes glioma angiogenesis by activating NF-κB signalingPcif1 modulates Pdx1 protein stability and pancreatic β cell function and survival in miceLong noncoding RNA variations in cardiometabolic diseases.Islet biology, the CDKN2A/B locus and type 2 diabetes risk.Activation of Wnt/β-catenin signaling by lithium chloride attenuates d-galactose-induced neurodegeneration in the auditory cortex of a rat model of aging.Expression of linear and novel circular forms of an INK4/ARF-associated non-coding RNA correlates with atherosclerosis risk.Postnatal development, maturation and aging in the mouse cochlea and their effects on hair cell regeneration.Adaptive changes in pancreatic beta cell fractional area and beta cell turnover in human pregnancy.Islet microenvironment, modulated by vascular endothelial growth factor-A signaling, promotes β cell regeneration.Impact papers on aging in 2009.Chromatin modifications as determinants of muscle stem cell quiescence and chronological aging.Tissue-specific p19Arf regulation dictates the response to oncogenic K-ras.Superior efficacy of a combined epigenetic therapy against human mantle cell lymphoma cells.Gene expression profiles of Beta-cell enriched tissue obtained by laser capture microdissection from subjects with type 2 diabetes.The molecular balancing act of p16(INK4a) in cancer and aging.Glucose and aging control the quiescence period that follows pancreatic beta cell replicationAge-related impairment of pancreatic Beta-cell function: pathophysiological and cellular mechanisms.Identification and characterization of Bmi-1-responding element within the human p16 promoter.Co-delivery of doxorubicin and Bmi1 siRNA by folate receptor targeted liposomes exhibits enhanced anti-tumor effects in vitro and in vivo.Aging, rejuvenation, and epigenetic reprogramming: resetting the aging clock.Pancreatic beta-cells: from generation to regeneration.Bmi-1 promotes the aggressiveness of glioma via activating the NF-kappaB/MMP-9 signaling pathway.The Polycomb protein, Bmi1, regulates insulin sensitivityBmi1 enhances tumorigenicity and cancer stem cell function in pancreatic adenocarcinoma.Validation of Bmi1 as a therapeutic target of hepatocellular carcinoma in mice.Epigenetic mechanisms in diabetic vascular complications.Heavy metals and epigenetic alterations in brain tumors.A systems view of epigenetic networks regulating pancreas development and β-cell functionDeconstructing pancreas development to reconstruct human islets from pluripotent stem cells.The histone lysine demethylase JMJD3/KDM6B is recruited to p53 bound promoters and enhancer elements in a p53 dependent manner.Type 2 diabetes and the aging pancreatic beta cell.Transgenic overexpression of the transcription factor Nkx6.1 in β-cells of mice does not increase β-cell proliferation, β-cell mass, or improve glucose clearance.
P2860
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P2860
Bmi-1 regulates the Ink4a/Arf locus to control pancreatic beta-cell proliferation.
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article científic
@ca
article scientifique
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articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on April 2009
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Bmi-1 regulates the Ink4a/Arf locus to control pancreatic beta-cell proliferation.
@en
Bmi-1 regulates the Ink4a/Arf locus to control pancreatic beta-cell proliferation.
@nl
type
label
Bmi-1 regulates the Ink4a/Arf locus to control pancreatic beta-cell proliferation.
@en
Bmi-1 regulates the Ink4a/Arf locus to control pancreatic beta-cell proliferation.
@nl
prefLabel
Bmi-1 regulates the Ink4a/Arf locus to control pancreatic beta-cell proliferation.
@en
Bmi-1 regulates the Ink4a/Arf locus to control pancreatic beta-cell proliferation.
@nl
P2093
P2860
P356
P1433
P1476
Bmi-1 regulates the Ink4a/Arf locus to control pancreatic beta-cell proliferation.
@en
P2093
Anil Bhushan
Sangeeta Dhawan
Shuen-Ing Tschen
P2860
P304
P356
10.1101/GAD.1742609
P577
2009-04-01T00:00:00Z