Pim-1 kinase expression predicts radiation response in squamocellular carcinoma of head and neck and is under the control of epidermal growth factor receptor.
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PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancersDinosaurs and ancient civilizations: reflections on the treatment of cancerPim Kinases Promote Migration and Metastatic Growth of Prostate Cancer XenograftsTricyclic Benzo[cd]azulenes selectively inhibit activities of Pim kinases and restrict growth of Epstein-Barr virus-transformed cellsAssociation of Nuclear PIM1 Expression with Lymph Node Metastasis and Poor Prognosis in Patients with Lung Adenocarcinoma and Squamous Cell CarcinomaPIM1 kinase as a target for cancer therapyPim-selective inhibitor DHPCC-9 reveals Pim kinases as potent stimulators of cancer cell migration and invasionERG deregulation induces PIM1 over-expression and aneuploidy in prostate epithelial cells.Pim-1 kinase is a target of miR-486-5p and eukaryotic translation initiation factor 4E, and plays a critical role in lung cancer.The mRNA-binding protein HuR promotes hypoxia-induced chemoresistance through posttranscriptional regulation of the proto-oncogene PIM1 in pancreatic cancer cells.EGFR targeting drugs in the treatment of head and neck squamous cell carcinoma.The oncogenic kinase Pim-1 is modulated by K-Ras signaling and mediates transformed growth and radioresistance in human pancreatic ductal adenocarcinoma cells.Pim1 kinase is upregulated in glioblastoma multiforme and mediates tumor cell survival.Expression of pim-1 in tumors, tumor stroma and tumor-adjacent mucosa co-determines the prognosis of colon cancer patients.EBNA3C augments Pim-1 mediated phosphorylation and degradation of p21 to promote B-cell proliferationThe interconnectedness of cancer cell signaling.Human CD180 Transmits Signals via the PIM-1L Kinase.PIM kinases are progression markers and emerging therapeutic targets in diffuse large B-cell lymphoma.MicroRNA-101-3p suppresses cell proliferation, invasion and enhances chemotherapeutic sensitivity in salivary gland adenoid cystic carcinoma by targeting Pim-1.PIM-1 contributes to the malignancy of pancreatic cancer and displays diagnostic and prognostic value.The War on Cancer rages on.Why target PIM1 for cancer diagnosis and treatment?For better or for worse: the role of Pim oncogenes in tumorigenesis.The PIM family of serine/threonine kinases in cancer.PIM kinases: an overview in tumors and recent advances in pancreatic cancer.Loss of PIM2 enhances the anti-proliferative effect of the pan-PIM kinase inhibitor AZD1208 in non-Hodgkin lymphomas.Regulation of prostate stromal fibroblasts by the PIM1 protein kinase.Pim kinase isoforms: devils defending cancer cells from therapeutic and immune attacks.The direct Myc target Pim3 cooperates with other Pim kinases in supporting viability of Myc-induced B-cell lymphomas.p53-dependent induction of prostate cancer cell senescence by the PIM1 protein kinaseA potential therapeutic target for FLT3-ITD AML: PIM1 kinase.Thyroid hormone inhibits growth of hepatoma cells through induction of miR-214.PI3K-like kinases restrain Pim gene expression in endothelial cells.PIM Kinases and Their Relevance to the PI3K/AKT/mTOR Pathway in the Regulation of Ovarian Cancer.Preclinical characterization of INCB053914, a novel pan-PIM kinase inhibitor, alone and in combination with anticancer agents, in models of hematologic malignancies.
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Pim-1 kinase expression predicts radiation response in squamocellular carcinoma of head and neck and is under the control of epidermal growth factor receptor.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Pim-1 kinase expression predic ...... dermal growth factor receptor.
@en
Pim-1 kinase expression predic ...... dermal growth factor receptor.
@nl
type
label
Pim-1 kinase expression predic ...... dermal growth factor receptor.
@en
Pim-1 kinase expression predic ...... dermal growth factor receptor.
@nl
prefLabel
Pim-1 kinase expression predic ...... dermal growth factor receptor.
@en
Pim-1 kinase expression predic ...... dermal growth factor receptor.
@nl
P2093
P2860
P50
P356
P1433
P1476
Pim-1 kinase expression predic ...... idermal growth factor receptor
@en
P2093
Jouko Sandholm
Katriina Peltola
Maria Sundvall
Marjaana Luukkaa
Päivi J Koskinen
Raija Ristamäki
Reidar Grenman
Sanna-Mari Maula
Sirpa Jalkanen
P2860
P304
P356
10.1593/NEO.81038
P577
2009-07-01T00:00:00Z