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Brain region specific mitophagy capacity could contribute to selective neuronal vulnerability in Parkinson's diseaseTowards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examplesLeucine-rich repeat kinase 2 disturbs mitochondrial dynamics via Dynamin-like proteinEmerging modes of PINK1 signaling: another task for MARK2Novel super-resolution capable mitochondrial probe, MitoRed AIE, enables assessment of real-time molecular mitochondrial dynamics.What is the function of mitochondrial networks? A theoretical assessment of hypotheses and proposal for future researchGlutamate excitotoxicity in neurons triggers mitochondrial and endoplasmic reticulum accumulation of Parkin, and, in the presence of N-acetyl cysteine, mitophagyHow Parkinsonian toxins dysregulate the autophagy machineryReduced axonal transport in Parkinson's disease cybrid neurites is restored by light therapy.Bioenergetics of neurons inhibit the translocation response of Parkin following rapid mitochondrial depolarization.DJ-1 knock-down impairs astrocyte mitochondrial function.Computational deconvolution of genome wide expression data from Parkinson's and Huntington's disease brain tissues using population-specific expression analysis.Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson's disease modelsModelling the role of UCH-L1 on protein aggregation in age-related neurodegeneration.Mitochondrial oxidative stress causes mitochondrial fragmentation via differential modulation of mitochondrial fission-fusion proteins.Drosophila melanogaster in the study of human neurodegeneration.Beyond the mitochondrion: cytosolic PINK1 remodels dendrites through protein kinase AIntegrating multiple aspects of mitochondrial dynamics in neurons: age-related differences and dynamic changes in a chronic rotenone model.Mitochondrial dynamics in diabetes.Hyperglycemia- and neuropathy-induced changes in mitochondria within sensory nerves.Modulation of mitochondrial function and morphology by interaction of Omi/HtrA2 with the mitochondrial fusion factor OPA1.Parkin ubiquitinates Drp1 for proteasome-dependent degradation: implication of dysregulated mitochondrial dynamics in Parkinson diseaseMetabotropic glutamate receptor 5 antagonist protects dopaminergic and noradrenergic neurons from degeneration in MPTP-treated monkeys.Current Gaps in Understanding the Molecular Basis of FXTASL166P mutant DJ-1 promotes cell death by dissociating Bax from mitochondrial Bcl-XL.Automated and manual patch clamp data of human induced pluripotent stem cell-derived dopaminergic neuronsCognitive Impairment Associated with Parkinson's Disease: Role of Mitochondria.Tickled PINK1: mitochondrial homeostasis and autophagy in recessive Parkinsonism.Redox regulation of mitochondrial function with emphasis on cysteine oxidation reactions.Basic mechanisms of neurodegeneration: a critical update.Redox regulation of mitochondrial fission, protein misfolding, synaptic damage, and neuronal cell death: potential implications for Alzheimer's and Parkinson's diseases.Understanding the molecular basis of Parkinson's disease, identification of biomarkers and routes to therapy.S-nitrosylation of critical protein thiols mediates protein misfolding and mitochondrial dysfunction in neurodegenerative diseases.Redox modulation by S-nitrosylation contributes to protein misfolding, mitochondrial dynamics, and neuronal synaptic damage in neurodegenerative diseases.Parkin, PINK1 and mitochondrial integrity: emerging concepts of mitochondrial dysfunction in Parkinson's disease.Multipolar functions of BCL-2 proteins link energetics to apoptosisThe interplay of neuronal mitochondrial dynamics and bioenergetics: implications for Parkinson's diseaseMitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences.Impairment of mitochondria dynamics by human A53T α-synuclein and rescue by NAP (davunetide) in a cell model for Parkinson's disease.Orexin A attenuates palmitic acid-induced hypothalamic cell death
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 28 March 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Mitochondrial dynamics in Parkinson's disease.
@en
Mitochondrial dynamics in Parkinson's disease.
@nl
type
label
Mitochondrial dynamics in Parkinson's disease.
@en
Mitochondrial dynamics in Parkinson's disease.
@nl
prefLabel
Mitochondrial dynamics in Parkinson's disease.
@en
Mitochondrial dynamics in Parkinson's disease.
@nl
P2860
P1476
Mitochondrial dynamics in Parkinson's disease.
@en
P2093
Sarah B Berman
Victor S Van Laar
P2860
P304
P356
10.1016/J.EXPNEUROL.2009.03.019
P4011
5b3c515d78adfec1781e2ba02ab7547221d6f97d
P407
P577
2009-03-28T00:00:00Z