Regulation of IRF-3-dependent innate immunity by the papain-like protease domain of the severe acute respiratory syndrome coronavirus
about
Herpes simplex virus 1 tegument protein US11 downmodulates the RLR signaling pathway via direct interaction with RIG-I and MDA-5Antiviral activities of ISG20 in positive-strand RNA virus infectionsEvasion of antiviral immunity through sequestering of TBK1/IKKε/IRF3 into viral inclusion bodiesNidovirus papain-like proteases: multifunctional enzymes with protease, deubiquitinating and deISGylating activitiesCoronavirus virulence genes with main focus on SARS-CoV envelope geneFrom SARS to MERS: crystallographic studies on coronaviral proteases enable antiviral drug designToll-like receptors in antiviral innate immunityViral OTU deubiquitinases: a structural and functional comparisonCoronavirus Infection Modulates the Unfolded Protein Response and Mediates Sustained Translational RepressionToll-Like Receptor 3 Mediates Establishment of an Antiviral State against Hepatitis C Virus in Hepatoma CellsCrystal structures of the X-domains of a Group-1 and a Group-3 coronavirus reveal that ADP-ribose-binding may not be a conserved propertyThe SARS-Unique Domain (SUD) of SARS Coronavirus Contains Two Macrodomains That Bind G-QuadruplexesSevere Acute Respiratory Syndrome Coronavirus Papain-like Novel Protease Inhibitors: Design, Synthesis, Protein−Ligand X-ray Structure and Biological EvaluationDeubiquitinase function of arterivirus papain-like protease 2 suppresses the innate immune response in infected host cellsX-ray Structural and Biological Evaluation of a Series of Potent and Highly Selective Inhibitors of Human Coronavirus Papain-like ProteasesStructural Basis for the Ubiquitin-Linkage Specificity and deISGylating Activity of SARS-CoV Papain-Like ProteaseVaricella-zoster virus immediate-early protein ORF61 abrogates the IRF3-mediated innate immune response through degradation of activated IRF3Genomic characterization of severe acute respiratory syndrome-related coronavirus in European bats and classification of coronaviruses based on partial RNA-dependent RNA polymerase gene sequencesProtein Interferon-Stimulated Gene 15 Conjugation Delays but Does Not Overcome Coronavirus Proliferation in a Model of Fulminant HepatitisPotent and selective inhibition of pathogenic viruses by engineered ubiquitin variants.The SARS-coronavirus papain-like protease: structure, function and inhibition by designed antiviral compounds.Interaction between innate immunity and porcine reproductive and respiratory syndrome virus.The zinc-finger domain was essential for porcine reproductive and respiratory syndrome virus nonstructural protein-1α to inhibit the production of interferon-β.Novel influenza virus NS1 antagonists block replication and restore innate immune function.PLP2 of mouse hepatitis virus A59 (MHV-A59) targets TBK1 to negatively regulate cellular type I interferon signaling pathway.A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication.Structure-based design, synthesis, and biological evaluation of a series of novel and reversible inhibitors for the severe acute respiratory syndrome-coronavirus papain-like protease.Pathogenicity of severe acute respiratory coronavirus deletion mutants in hACE-2 transgenic mice.Chiropteran types I and II interferon genes inferred from genome sequencing traces by a statistical gene-family assembler.Coronaviruses post-SARS: update on replication and pathogenesis.Deubiquitinating and interferon antagonism activities of coronavirus papain-like proteases.Mechanisms of severe acute respiratory syndrome pathogenesis and innate immunomodulation.Pathogenesis of murine coronavirus in the central nervous system.Accessory protein 5a is a major antagonist of the antiviral action of interferon against murine coronavirus.Porcine epidemic diarrhea virus nucleocapsid protein antagonizes beta interferon production by sequestering the interaction between IRF3 and TBK1.Coronavirus papain-like proteases negatively regulate antiviral innate immune response through disruption of STING-mediated signalingAutocrine interferon priming in macrophages but not dendritic cells results in enhanced cytokine and chemokine production after coronavirus infectionMurine coronavirus ubiquitin-like domain is important for papain-like protease stability and viral pathogenesis.Middle East respiratory syndrome coronavirus: another zoonotic betacoronavirus causing SARS-like diseaseThe role of viral population diversity in adaptation of bovine coronavirus to new host environments
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P2860
Regulation of IRF-3-dependent innate immunity by the papain-like protease domain of the severe acute respiratory syndrome coronavirus
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 30 August 2007
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Regulation of IRF-3-dependent ...... spiratory syndrome coronavirus
@en
Regulation of IRF-3-dependent ...... piratory syndrome coronavirus.
@nl
type
label
Regulation of IRF-3-dependent ...... spiratory syndrome coronavirus
@en
Regulation of IRF-3-dependent ...... piratory syndrome coronavirus.
@nl
prefLabel
Regulation of IRF-3-dependent ...... spiratory syndrome coronavirus
@en
Regulation of IRF-3-dependent ...... piratory syndrome coronavirus.
@nl
P2093
P2860
P356
P1476
Regulation of IRF-3-dependent ...... spiratory syndrome coronavirus
@en
P2093
Chien-Te K Tseng
Monica Tseng
Naina Barretto
Rongtuan Lin
Santhana G Devaraj
Susan C Baker
Zhongbin Chen
Zihong Chen
P2860
P304
32208-32221
P356
10.1074/JBC.M704870200
P407
P577
2007-08-30T00:00:00Z