Angiotensin II-dependent TGF-β signaling contributes to Loeys-Dietz syndrome vascular pathogenesis - Wikidata - awgldk - TriplyDB

Angiotensin II-dependent TGF-β signaling contributes to Loeys-Dietz syndrome vascular pathogenesis

Angiotensin II-dependent TGF-β signaling contributes to Loeys-Dietz syndrome vascular pathogenesis

http://www.wikidata.org/entity/Q37410582

about

Regulatory RNAs controlling vascular (dys)function by affecting TGF-ß family signalling Current Controversies in Diagnosis and Management of Cleft Palate and Velopharyngeal Insufficiency.The role of transforming growth factor β1 in the regulation of blood pressure Fibulin-4 is essential for maintaining arterial wall integrity in conduit but not muscular arteries.MiR-125b Is Critical for Fibroblast-to-Myofibroblast Transition and Cardiac Fibrosis.The Pathogenic Transforming Growth Factor-β Overdrive Hypothesis in Aortic Aneurysms and Dissections: A Mirage?The pathobiology of vascular malformations: insights from human and model organism genetics.Early-lethal Costello syndrome due to rare HRAS Tandem Base substitution (c.35_36GC>AA; p.G12E)-associated pulmonary vascular disease Hypertension overrides the protective effect of female hormones on the development of aortic aneurysm secondary to Alk5 deficiency via ERK activation.Matrix metalloproteinases promote arterial remodeling in aging, hypertension, and atherosclerosis Mutations in a TGF-β ligand, TGFB3, cause syndromic aortic aneurysms and dissections.Role of mechanotransduction in vascular biology: focus on thoracic aortic aneurysms and dissections.TGF-β Neutralization Enhances AngII-Induced Aortic Rupture and Aneurysm in Both Thoracic and Abdominal Regions.A deleterious gene-by-environment interaction imposed by calcium channel blockers in Marfan syndrome.Long noncoding RNA AK056155 involved in the development of Loeys-Dietz syndrome through AKT/PI3K signaling pathway Genetic analysis of the contribution of LTBP-3 to thoracic aneurysm in Marfan syndrome.Fibulin-4 deficiency increases TGF-β signalling in aortic smooth muscle cells due to elevated TGF-β2 levels.Postnatal Deletion of the Type II Transforming Growth Factor-β Receptor in Smooth Muscle Cells Causes Severe Aortopathy in Mice Cathepsin-Mediated Alterations in TGFß-Related Signaling Underlie Disrupted Cartilage and Bone Maturation Associated With Impaired Lysosomal Targeting.Local Application of Leptin Antagonist Attenuates Angiotensin II-Induced Ascending Aortic Aneurysm and Cardiac Remodeling.β-Aminopropionitrile monofumarate induces thoracic aortic dissection in C57BL/6 mice.Insights into ascending aortic aneurysm pathogenesis using in vivo and ex vivo imaging systems in angiotensin II-infused mice Hereditary Influence in Thoracic Aortic Aneurysm and Dissection.Smooth muscle cell-specific Tgfbr1 deficiency promotes aortic aneurysm formation by stimulating multiple signaling events.Aortic aneurysms in Loeys-Dietz syndrome - a tale of two pathways?Experimental in vivo and ex vivo models for the study of human aortic dissection: promises and challenges Transforming growth factor beta1 and aldosterone.A healthy tension in translational research.From Genes to Mechanisms: The Expanding Spectrum of Monogenic Disorders Associated with Inflammatory Bowel Disease.Marfan Syndrome and Related Disorders: 25 Years of Gene Discovery.Pathophysiology of aortic aneurysm: insights from human genetics and mouse models.Aetiology and management of hereditary aortopathy.TGF-β Family Signaling in Connective Tissue and Skeletal Diseases.Function of Ltbp-4L and fibulin-4 in survival and elastogenesis in mice.Genes Associated with Thoracic Aortic Aneurysm and Dissection: An Update and Clinical Implications.Vascular Smooth Muscle Cells.Cytochrome P450 1B1 Contributes to the Development of Angiotensin II-Induced Aortic Aneurysm in Male Apoe(-/-) Mice.Angiotensin II induces region-specific medial disruption during evolution of ascending aortic aneurysms Molecular mechanisms of inherited thoracic aortic disease - from gene variant to surgical aneurysm.Transforming Growth Factor-β in Thoracic Aortic Aneurysms: Good, Bad, or Irrelevant?

P2860

Q26767134-D73943DC-D149-4984-B7FB-80C87DB26C9E Q26798156-F7FABCDD-494A-41EA-8D70-0D938FD05F02 Q26998564-AB9042B1-ADB8-4663-AB8A-5F70E9B5E78D Q33633336-1E2C708F-66AE-4DCF-B3AC-CACE98693098 Q33731819-5EB4CD6A-4A82-4801-A531-11BB49DF00D5 Q33736775-2D230381-9746-4528-8819-3479F3CA9814 Q34544980-274957C7-F985-45DD-8035-0A8FE64F904A Q34964138-618EBC3F-ACB7-47A2-9D74-B4558616DEB1 Q35115818-EAFB4CA4-B752-40F1-A98B-DD3C7269FDE8 Q35175533-147DD23C-3826-4D04-8B6E-58B3A1A1835B Q35234874-6AA01201-6D86-4ADC-954E-4B0BC7F19F65 Q35571996-B01473E2-78BB-41BF-8984-559910AD606C Q35996913-96925A6D-B1BC-4AE7-B2A6-8B5CF855B89C Q36210344-A8DDCA39-304A-4B40-93F0-1CEF71D22522 Q36261531-183E5FBA-C4AF-4EDF-B6B8-C60B5A733DD5 Q36300421-8FE2217C-4FE5-4AAE-9CFB-2048FFDDE190 Q36320690-1E2C6A3B-7775-492B-8445-17A23B2B7091 Q36551449-43964404-58FC-4316-A5EE-69C0E35152F8 Q36730987-CEFA2DF5-D21F-4A50-A81B-B6EEF6D4158A Q36956817-584B0966-B956-40F5-A827-C3CE5756B6FE Q37027472-9725E54B-3785-4736-BDBC-EB6AD60DD4F5 Q37208735-C3AA95C1-4704-4576-A650-34F851265AB7 Q37272866-1EA01384-3046-4CE6-AB9C-F1CD212BC835 Q37339708-A1F17531-58F8-42CF-8CA0-C769DE96C6DB Q37410646-D11B45F9-3AC8-4FFF-8517-DBD7CECC9585 Q37553691-E293867D-3256-4F33-8F31-18A92BBD519B Q38318139-026EB1DD-C26B-4DEF-8977-BB23D9AEC60A Q38592372-02DEBE26-B506-4BCA-91AD-BBF3B784E9F8 Q38619050-725F3B1E-C24C-4DEF-B1FF-3E0DCA7FC528 Q38751533-CBC05D70-DF2D-43D4-9828-886ED70951DB Q39030430-F05100F7-B74E-41E0-8891-F6743E33B8CF Q39094762-17EC94E3-2B1F-4D57-91BB-C0C0CEBBF253 Q39155183-AFDBD4AB-FA35-4252-9928-BE873408937D Q39431242-8388018D-BC01-487E-8EF7-A45F3E35F7FA Q41513957-9470F1BC-7EB9-4E7A-89AD-69E9F68E5BD0 Q41633099-B982AFEC-443F-4872-ABE2-77526C284C3C Q41817139-62958FCE-708D-4E0E-9C57-94A042A74113 Q41825777-A1291DC9-AE95-4AC1-9CD7-626BC5BE0AEF Q42185347-6573E1CD-94BB-4D29-8129-90A147EDFEB0 Q42336072-5B9FB430-55B0-4361-BCED-152B5D54C5A0

P2860

Angiotensin II-dependent TGF-β signaling contributes to Loeys-Dietz syndrome vascular pathogenesis

http://www.wikidata.org/entity/Q37410582

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 20 December 2013

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Angiotensin II-dependent TGF-β ...... syndrome vascular pathogenesis

@en

Angiotensin II-dependent TGF-β ...... yndrome vascular pathogenesis.

@nl

type

label

Angiotensin II-dependent TGF-β ...... syndrome vascular pathogenesis

@en

Angiotensin II-dependent TGF-β ...... yndrome vascular pathogenesis.

@nl

prefLabel

Angiotensin II-dependent TGF-β ...... syndrome vascular pathogenesis

@en

Angiotensin II-dependent TGF-β ...... yndrome vascular pathogenesis.

@nl

P1433

Q37410582-A286CBBF-F3CA-4476-94CD-82408E66F497

P1476

Q37410582-3D1E7D12-F9B0-4062-A4F8-A3F7D50E649A

P2093

Q37410582-3024E39C-6F9D-432B-B612-60E6C6A8A66B

Q37410582-4F66974D-3BB4-4BBF-B1D6-C1C5962C1C25

Q37410582-59ED2929-5BA1-42E2-9829-934FF15C4BD6

Q37410582-5BD4A2C2-995C-4BD8-B5B6-638BFCBC4F25

Q37410582-5DCAA0F9-7A1D-488A-87EF-189CED168CD4

Q37410582-7540B9B8-04A9-41D2-9631-B6D8E6A24C1F

Q37410582-8E28BA1A-C5A4-4AA3-B6C6-63B3E59257FA

Q37410582-999D8637-7159-461A-8122-C09DD6FE6805

Q37410582-9B4AC016-3161-4CDB-9E5D-BF7CDABBD3F6

Q37410582-9E93D74D-65C6-415E-A703-F07A52F45311

P2860

Q37410582-00DBACAA-F259-4E90-A77E-194D3443CBA5

Q37410582-13A74CB6-A080-44D7-A003-ADE791A53015

Q37410582-156747CF-2155-4435-A1E1-8286F56870E3

Q37410582-19C28F56-920D-41C6-BB55-88391839F196

Q37410582-2E767FDF-1C4D-41F2-969C-8178AE2B9B17

Q37410582-30606DAF-70CE-4680-9E5F-D5BC0B423338

Q37410582-35A85E14-6D8B-4036-99A7-4C5892C9423F

Q37410582-3DA68865-0710-4C83-93F4-80DC782D5BAB

Q37410582-3F6AB949-C3D9-4961-8C31-8447D4FBFA12

Q37410582-49F4BFE2-9386-4D0A-BADB-31260AFFDA2D

P304

Q37410582-5A855C5B-00CB-4BC5-8ABF-249A39DECD48

P31

Q37410582-4786A518-D6AA-44BF-84F1-A4188C27B55B

P356

Q37410582-2ECFB0BB-4028-42F2-9B9F-3C74289FD2A1

P407

Q37410582-E7297192-351B-4B5C-A1E7-C2C1D78B6C7A

P433

Q37410582-67AD1690-5924-405E-B31A-08295266CA24

P478

Q37410582-6AD978FE-BE52-4096-8463-6EC6D2D6C03C

P50

Q37410582-1E17D0C0-BE6E-4696-B9ED-85831B130EEB

Q37410582-AA6BC900-7AA1-4BDF-9531-4D3F3D76F4BF

P577

Q37410582-EA487810-65AE-4DFA-9203-EA634C289DCE

P698

Q37410582-0A1C3F68-5C4D-4C06-8406-6F85214A9E1A

P921

Q37410582-803811DA-8D82-4367-A0DB-45E3FCF74B79

P932

Q37410582-12F65D68-E153-46C6-BBEA-39D3BA7BD958

P356

P1433

Journal of Clinical Investigation

P1476

Angiotensin II-dependent TGF-β ...... syndrome vascular pathogenesis

@en

P2093

Christel van Erp

http://www.w3.org/2001/XMLSchema#string

Colette M ap Rhys

http://www.w3.org/2001/XMLSchema#string

David C Loch

http://www.w3.org/2001/XMLSchema#string

David L Huso

http://www.w3.org/2001/XMLSchema#string

Djahida Bedja

http://www.w3.org/2001/XMLSchema#string

Elena M Gallo

http://www.w3.org/2001/XMLSchema#string

Elizabeth E Gerber

http://www.w3.org/2001/XMLSchema#string

Harry C Dietz

http://www.w3.org/2001/XMLSchema#string

Jennifer P Habashi

http://www.w3.org/2001/XMLSchema#string

Kathleen C Kent

http://www.w3.org/2001/XMLSchema#string

P2860

TGF-β signalling is mediated by two autonomously functioning TβRI:TβRII pairs

Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

A syndrome of altered cardiovascular, craniofacial, neurocognitive and skeletal development caused by mutations in TGFBR1 or TGFBR2

Aneurysm syndromes caused by mutations in the TGF-beta receptor

Abnormal lung development and cleft palate in mice lacking TGF-beta 3 indicates defects of epithelial-mesenchymal interaction

Angiotensin II blockade and aortic-root dilation in Marfan's syndrome

Blocking Smad7 restores TGF-beta1 signaling in chronic inflammatory bowel disease

TGFbeta2 knockout mice have multiple developmental defects that are non-overlapping with other TGFbeta knockout phenotypes

Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta

P304

448-460

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1172/JCI69666

http://www.w3.org/2001/XMLSchema#string

P407

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

124

http://www.w3.org/2001/XMLSchema#string

P50

P577

2013-12-20T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

24355923

http://www.w3.org/2001/XMLSchema#string

P921

P932

3871227

http://www.w3.org/2001/XMLSchema#string