Greasing the wheels of Abeta clearance in Alzheimer's disease: the role of lipids and apolipoprotein E.
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Impact of apolipoprotein E on Alzheimer's diseaseThe pathogenic implication of abnormal interaction between apolipoprotein E isoforms, amyloid-beta peptides, and sulfatides in Alzheimer's diseaseApolipoprotein E: isoform specific differences in tertiary structure and interaction with amyloid-β in human Alzheimer brainATP-binding cassette transporter A1 mediates the beneficial effects of the liver X receptor agonist GW3965 on object recognition memory and amyloid burden in amyloid precursor protein/presenilin 1 mice.Effect of apolipoprotein E genotype and diet on apolipoprotein E lipidation and amyloid peptides: randomized clinical trialApolipoprotein E-low density lipoprotein receptor interaction affects spatial memory retention and brain ApoE levels in an isoform-dependent manner.Genomic convergence and network analysis approach to identify candidate genes in Alzheimer's disease.Metals and cholesterol: two sides of the same coin in Alzheimer's disease pathology.Retinoic acid isomers facilitate apolipoprotein E production and lipidation in astrocytes through the retinoid X receptor/retinoic acid receptor pathway.Vascular pathology in the aged human brainHuman ApoE Isoforms Differentially Modulate Glucose and Amyloid Metabolic Pathways in Female Brain: Evidence of the Mechanism of Neuroprotection by ApoE2 and Implications for Alzheimer's Disease Prevention and Early InterventionMetabolomic Profiling of Bile Acids in Clinical and Experimental Samples of Alzheimer's DiseaseThe vascular contribution to Alzheimer's disease.Modulation of γ-secretase activity by multiple enzyme-substrate interactions: implications in pathogenesis of Alzheimer's diseaseA multifaceted role for apoE in the clearance of beta-amyloid across the blood-brain barrier.Apolipoprotein E: from lipid transport to neurobiologyAn ABCA1-independent pathway for recycling a poorly lipidated 8.1 nm apolipoprotein E particle from glia.Retinoic acid isomers up-regulate ATP binding cassette A1 and G1 and cholesterol efflux in rat astrocytes: implications for their therapeutic and teratogenic effectsEvaluation of the global association between cholesterol-associated polymorphisms and Alzheimer's disease suggests a role for rs3846662 and HMGCR splicing in disease risk.Analysis of differential secondary effects of novel rexinoids: select rexinoid X receptor ligands demonstrate differentiated side effect profiles.Gene-activation mechanisms in the regression of atherosclerosis, elimination of diabetes type 2, and prevention of dementia.AP-2β regulates amyloid beta-protein stimulation of apolipoprotein E transcription in astrocytes.Sterol lipid metabolism in down syndrome revisited: down syndrome is associated with a selective reduction in serum brassicasterol levelsRole of ABC transporters in the pathogenesis of Alzheimer's diseaseThe plaque "micro" environment: microRNAs control the risk and the development of atherosclerosis.Elimination of endoplasmic reticulum stress and cardiovascular, type 2 diabetic, and other metabolic diseases.Characterization of insulin degrading enzyme and other amyloid-β degrading proteases in human serum: a role in Alzheimer's disease?Insulin resistance, dyslipidemia, and apolipoprotein E interactions as mechanisms in cognitive impairment and Alzheimer's diseaseLiver X receptor modulators: a review of recently patented compounds (2007 - 2009).Direct binding of cholesterol to the amyloid precursor protein: An important interaction in lipid-Alzheimer's disease relationships?Current therapeutic targets for the treatment of Alzheimer's disease.Current strategies in the discovery of small-molecule biomarkers for Alzheimer's disease.Transgenic mouse models of Alzheimer disease: developing a better model as a tool for therapeutic interventions.The role of cholesterol metabolism in Alzheimer's disease.HDL and cholesterol handling in the brain.Cerebrospinal fluid steroidomics: are bioactive bile acids present in brain?ApoE rs429358 and rs7412 Polymorphism and Gender Differences of Serum Lipid Profile and Cognition in Aging Chinese PopulationRosiglitazone rescues memory impairment in Alzheimer's transgenic mice: mechanisms involving a reduced amyloid and tau pathology.MiR-106b impairs cholesterol efflux and increases Aβ levels by repressing ABCA1 expression.Curcumin induces ABCA1 expression and apolipoprotein A-I-mediated cholesterol transmembrane in the chronic cerebral hypoperfusion aging rats.
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P2860
Greasing the wheels of Abeta clearance in Alzheimer's disease: the role of lipids and apolipoprotein E.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Greasing the wheels of Abeta c ...... f lipids and apolipoprotein E.
@en
Greasing the wheels of Abeta c ...... f lipids and apolipoprotein E.
@nl
type
label
Greasing the wheels of Abeta c ...... f lipids and apolipoprotein E.
@en
Greasing the wheels of Abeta c ...... f lipids and apolipoprotein E.
@nl
prefLabel
Greasing the wheels of Abeta c ...... f lipids and apolipoprotein E.
@en
Greasing the wheels of Abeta c ...... f lipids and apolipoprotein E.
@nl
P2093
P2860
P356
P1433
P1476
Greasing the wheels of Abeta c ...... f lipids and apolipoprotein E.
@en
P2093
Cheryl Wellington
James Donkin
Jianjia Fan
P2860
P304
P356
10.1002/BIOF.37
P577
2009-05-01T00:00:00Z