A soluble, single-chain T-cell receptor fragment endowed with antigen-combining properties.
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Selection of functional T cell receptor mutants from a yeast surface-display libraryFunctional glycan-free adhesion domain of human cell surface receptor CD58: design, production and NMR studiesCloning and expression of human membrane-bound and soluble engineered T cell receptors for immunotherapy.Periplasmic expression of soluble single chain T cell receptors is rescued by the chaperone FkpA.Stabilizing mutations increase secretion of functional soluble TCR-Ig fusion proteins.T-cell-mediated autoimmunity: novel techniques to characterize autoreactive T-cell receptorsBinding of soluble natural ligands to a soluble human T-cell receptor fragment produced in Escherichia coli.Autoantibodies to the alpha/beta T-cell receptors in human immunodeficiency virus infection: dysregulation and mimicry.A general method for facilitating heterodimeric pairing between two proteins: application to expression of alpha and beta T-cell receptor extracellular segments.Functional three-domain single-chain T-cell receptorsInhibition or activation of human T cell receptor transfectants is controlled by defined, soluble antigen arrays.A bacterially expressed single-chain Fv construct from the 2B4 T-cell receptor.Cloning, expression, and crystallization of the V delta domain of a human gamma delta T-cell receptor.Immunization with soluble BDC 2.5 T cell receptor-immunoglobulin chimeric protein:antibody specificity and protection of nonobese diabetic mice against adoptive transfer of diabetes by maternal immunization.Strategies for achieving high-level expression of genes in Escherichia coli.Medical applications of single-chain antibodies.Characterization of a single-chain T-cell receptor expressed in Escherichia coliVaccination with single chain antigen receptors for islet-derived peptides presented on I-A(g7) delays diabetes in NOD mice by inducing anergy in self-reactiveT-cells.Similarity between fluorescein-specific T-cell receptor and antibody in chemical details of antigen recognition.Covalent assembly of a soluble T cell receptor-peptide-major histocompatibility class I complex.In-cell PCR from mRNA: amplifying and linking the rearranged immunoglobulin heavy and light chain V-genes within single cells.Transgenic TCR expression: comparison of single chain with full-length receptor constructs for T-cell function.Antigen recognition and targeted delivery by the single-chain Fv.Predicted complementarity determining regions of the T cell antigen receptor determine antigen specificity.Cells expressing a major histocompatibility complex class I molecule with a single covalently bound peptide are highly immunogenic.Structural features of T cell receptor variable regions that enhance domain stability and enable expression as single-chain ValphaVbeta fragmentsConformational integrity and ligand binding properties of a single chain T-cell receptor expressed in Escherichia coli.Directed evolution of a stable scaffold for T-cell receptor engineering.Soluble T-cell receptor design influences functional yield in an E. coli chaperone-assisted expression system.
P2860
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P2860
A soluble, single-chain T-cell receptor fragment endowed with antigen-combining properties.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on October 1991
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
A soluble, single-chain T-cell ...... antigen-combining properties.
@en
A soluble, single-chain T-cell ...... antigen-combining properties.
@nl
type
label
A soluble, single-chain T-cell ...... antigen-combining properties.
@en
A soluble, single-chain T-cell ...... antigen-combining properties.
@nl
prefLabel
A soluble, single-chain T-cell ...... antigen-combining properties.
@en
A soluble, single-chain T-cell ...... antigen-combining properties.
@nl
P2093
P2860
P356
P1476
A soluble, single-chain T-cell ...... antigen-combining properties.
@en
P2093
Reinherz EL
Siliciano RF
P2860
P304
P356
10.1073/PNAS.88.19.8646
P407
P577
1991-10-01T00:00:00Z