Extensive contribution of Rb-deficient cells to adult chimeric mice with limited histopathological consequences
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pRb inactivation in mammary cells reveals common mechanisms for tumor initiation and progression in divergent epitheliaTargeted disruption of the ubiquitous CNC-bZIP transcription factor, Nrf-1, results in anemia and embryonic lethality in mice.Fli-1, an Ets-related transcription factor, regulates erythropoietin-induced erythroid proliferation and differentiation: evidence for direct transcriptional repression of the Rb gene during differentiation.A pentamer transcriptional complex including tal-1 and retinoblastoma protein downmodulates c-kit expression in normal erythroblastsPAM14, a novel MRG- and Rb-associated protein, is not required for development and T-cell function in miceTid1, a cochaperone of the heat shock 70 protein and the mammalian counterpart of the Drosophila tumor suppressor l(2)tid, is critical for early embryonic development and cell survivalDifferential gene expression of p27Kip1 and Rb knockout pituitary tumors associated with altered growth and angiogenesisTransgenic Models in Retinoblastoma ResearchDistinct genetic alterations in small cell carcinoma from different anatomic sitesTissue-specific tumor suppressor activity of retinoblastoma gene homologs p107 and p130The scl gene product is required for the generation of all hematopoietic lineages in the adult mouseRepression by RB1 characterizes genes involved in the penultimate stage of erythroid developmentLens complementation system for the genetic analysis of growth, differentiation, and apoptosis in vivo.E2F4 cooperates with pRB in the development of extra-embryonic tissues.Dual loss of rb1 and Trp53 in the adrenal medulla leads to spontaneous pheochromocytoma.p19Ink4d is a tumor suppressor and controls pituitary anterior lobe cell proliferationTumour suppressor gene mutations in humans and mice: parallels and contrastsFunctional interactions between retinoblastoma and c-MYC in a mouse model of hepatocellular carcinoma.Cell-autonomous and non-cell-autonomous functions of the Rb tumor suppressor in developing central nervous system.Rescue of myogenic defects in Rb-deficient cells by inhibition of autophagy or by hypoxia-induced glycolytic shift.Tumor suppression by a severely truncated species of retinoblastoma protein.The role of the RB tumour suppressor pathway in oxidative stress responses in the haematopoietic system.An E2F binding-deficient Rb1 protein partially rescues developmental defects associated with Rb1 nullizygosity.ARF mutation accelerates pituitary tumor development in Rb+/- mice.Conditional mutation of Rb causes cell cycle defects without apoptosis in the central nervous system.Cell-nonautonomous function of the retinoblastoma tumour suppressor protein: new interpretations of old phenotypes.pRb-Independent growth arrest and transcriptional regulation of E2F target genesEmerging roles of E2Fs in cancer: an exit from cell cycle controlTransgenic and knockout mice models to reveal the functions of tumor suppressor genes.K-ras is an essential gene in the mouse with partial functional overlap with N-ras.p107 is a suppressor of retinoblastoma development in pRb-deficient mice.Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization.CDK inhibitors p18(INK4c) and p27(Kip1) mediate two separate pathways to collaboratively suppress pituitary tumorigenesis.Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway.Characterization of the cell of origin for small cell lung cancerThe erythroblastic islandMurine bilateral retinoblastoma exhibiting rapid-onset, metastatic progression and N-myc gene amplificationGenetic evidence for functional dependency of p18Ink4c on Cdk4.Selective requirements for E2f3 in the development and tumorigenicity of Rb-deficient chimeric tissues.Unique requirement for Rb/E2F3 in neuronal migration: evidence for cell cycle-independent functions
P2860
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P2860
Extensive contribution of Rb-deficient cells to adult chimeric mice with limited histopathological consequences
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on September 1994
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Extensive contribution of Rb-d ...... histopathological consequences
@en
Extensive contribution of Rb-d ...... istopathological consequences.
@nl
type
label
Extensive contribution of Rb-d ...... histopathological consequences
@en
Extensive contribution of Rb-d ...... istopathological consequences.
@nl
prefLabel
Extensive contribution of Rb-d ...... histopathological consequences
@en
Extensive contribution of Rb-d ...... istopathological consequences.
@nl
P2093
P2860
P1433
P1476
Extensive contribution of Rb-d ...... histopathological consequences
@en
P2093
B O Williams
D M Albert
E M Schmitt
L Remington
R A Weinberg
R T Bronson
P2860
P304
P407
P577
1994-09-01T00:00:00Z