Inhibition of vascular endothelial growth factor with a sequence-specific hypoxia response element antagonist.
about
Suppression of androgen receptor-mediated gene expression by a sequence-specific DNA-binding polyamideAlkylation of template strand of coding region causes effective gene silencingEpithelial-to-endothelial transition and cancer stem cells: two cornerstones of vasculogenic mimicry in malignant tumorsTargeting Protein-Protein Interactions in the HIF SystemAllosteric modulation of DNA by small moleculesStructural Basis for Cyclic Py-Im Polyamide Allosteric Inhibition of Nuclear Receptor BindingA multinodular goiter as the initial presentation of a renal cell carcinoma harbouring a novel VHL mutation.Improved nuclear localization of DNA-binding polyamides.Design and synthesis of a cell-permeable synthetic transcription factor mimic.Next generation hairpin polyamides with (R)-3,4-diaminobutyric acid turn unit.Quantitating the concentration of Py-Im polyamide-fluorescein conjugates in live cellsCompletion of a Programmable DNA-Binding Small Molecule LibraryModifications at the C-terminus to improve pyrrole-imidazole polyamide activity in cell culture.Inhibition of hypoxia-inducible factor-1alpha (HIF-1alpha) protein synthesis by DNA damage inducing agentsIn vivo modulation of hypoxia-inducible signaling by topographical helix mimetics.Development of HIF-1 inhibitors for cancer therapySpecificity landscapes of DNA binding molecules elucidate biological functionAltered cytokine profiles in patients with Chuvash polycythemia.Number of polyploid giant cancer cells and expression of EZH2 are associated with VM formation and tumor grade in human ovarian tumor.Angiogenesis inhibitors: current strategies and future prospects.Mini review: protein-protein interactions in transcription: a fertile ground for helix mimetics.DNA-binding small molecules as inhibitors of transcription factors.Noncanonical mechanisms to regulate nuclear receptor signaling.Controlling gene networks and cell fate with precision-targeted DNA-binding proteins and small-molecule-based genome readers.Targeting CREB for cancer therapy: friend or foeSynthesis of cyclic Py-Im polyamide libraries.DNA sequence selectivity of hairpin polyamide turn unitsQuantitative microarray profiling of DNA-binding moleculesInhibition of the HIF1α-p300 interaction by quinone- and indandione-mediated ejection of structural Zn(II).Differential disruption of EWS-FLI1 binding by DNA-binding agents.CCAAT/enhancer-binding protein beta: its role in breast cancer and associations with receptor tyrosine kinases.A therapeutic role for targeting c-Myc/Hif-1-dependent signaling pathways.Expanding the repertoire of natural product-inspired ring pairs for molecular recognition of DNA.Advancing small-molecule-based chemical biology with next-generation sequencing technologies.Programmable oligomers targeting 5'-GGGG-3' in the minor groove of DNA and NF-kappaB binding inhibition.Unanticipated differences between alpha- and gamma-diaminobutyric acid-linked hairpin polyamide-alkylator conjugates.Modulation of NF-κB-dependent gene transcription using programmable DNA minor groove bindersEnhancing the cellular uptake of Py-Im polyamides through next-generation aryl turns.Tumor Repression of VCaP Xenografts by a Pyrrole-Imidazole Polyamide.Pharmacokinetics of Py-Im polyamides depend on architecture: cyclic versus linear.
P2860
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P2860
Inhibition of vascular endothelial growth factor with a sequence-specific hypoxia response element antagonist.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Inhibition of vascular endothe ...... a response element antagonist.
@en
Inhibition of vascular endothe ...... a response element antagonist.
@nl
type
label
Inhibition of vascular endothe ...... a response element antagonist.
@en
Inhibition of vascular endothe ...... a response element antagonist.
@nl
prefLabel
Inhibition of vascular endothe ...... a response element antagonist.
@en
Inhibition of vascular endothe ...... a response element antagonist.
@nl
P2093
P2860
P921
P356
P1476
Inhibition of vascular endothe ...... a response element antagonist.
@en
P2093
Bogdan Z Olenyuk
Guo-Jun Zhang
Jeffery M Klco
Nicholas G Nickols
P2860
P304
16768-16773
P356
10.1073/PNAS.0407617101
P407
P577
2004-11-19T00:00:00Z