Identification of residues that control specific binding of the Shc phosphotyrosine-binding domain to phosphotyrosine sites.
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Interaction of c-Jun amino-terminal kinase interacting protein-1 with p190 rhoGEF and its localization in differentiated neuronsEfficient T-cell receptor signaling requires a high-affinity interaction between the Gads C-SH3 domain and the SLP-76 RxxK motifAdaptor ShcA protein binds tyrosine kinase Tie2 receptor and regulates migration and sprouting but not survival of endothelial cellsThe phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor proteinInteraction of phosphorylated FcepsilonRIgamma immunoglobulin receptor tyrosine activation motif-based peptides with dual and single SH2 domains of p72syk. Assessment of binding parameters and real time binding kineticsSequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domainDissecting the thrombopoietin receptor: functional elements of the Mpl cytoplasmic domainA mammalian adaptor protein with conserved Src homology 2 and phosphotyrosine-binding domains is related to Shc and is specifically expressed in the brainA unique autophosphorylation site on Tie2/Tek mediates Dok-R phosphotyrosine binding domain binding and functionMultiple modes of peptide recognition by the PTB domain of the cell fate determinant NumbStructure of a Numb PTB domain-peptide complex suggests a basis for diverse binding specificityRe-engineering the target specificity of the insulin receptor by modification of a PTB domain binding siteRole of Gab proteins in phosphatidylinositol 3-kinase activation by thrombopoietin (Tpo)Interaction domains: from simple binding events to complex cellular behaviorShcB and ShcC activation by the Trk family of receptor tyrosine kinasesN-Shc and Sck, two neuronally expressed Shc adapter homologs. Their differential regional expression in the brain and roles in neurotrophin and Src signaling'Srcasm: a novel Src activating and signaling moleculeAnalysis of a Shc family adaptor protein, ShcD/Shc4, that associates with muscle-specific kinaseThe mammalian numb phosphotyrosine-binding domain. Characterization of binding specificity and identification of a novel PDZ domain-containing numb binding protein, LNXGenetic identification of effectors downstream of Neu (ErbB-2) autophosphorylation sites in a Drosophila modelShc interaction with Src homology 2 domain containing inositol phosphatase (SHIP) in vivo requires the Shc-phosphotyrosine binding domain and two specific phosphotyrosines on SHIPEvidence for a requirement for both phospholipid and phosphotyrosine binding via the Shc phosphotyrosine-binding domain in vivoTyrosine phosphorylation of the beta 4 integrin cytoplasmic domain mediates Shc signaling to extracellular signal-regulated kinase and antagonizes formation of hemidesmosomes.The bldD gene of Streptomyces coelicolor A3(2): a regulatory gene involved in morphogenesis and antibiotic production.Intrasteric inhibition of ATP binding is not required to prevent unregulated autophosphorylation or signaling by the insulin receptor.Lessons in signaling and tumorigenesis from polyomavirus middle T antigen.The LDL receptor clustering motif interacts with the clathrin terminal domain in a reverse turn conformationRecruitment and phosphorylation of SH2-containing inositol phosphatase and Shc to the B-cell Fc gamma immunoreceptor tyrosine-based inhibition motif peptide motif.High-affinity binding of the Drosophila Numb phosphotyrosine-binding domain to peptides containing a Gly-Pro-(p)Tyr motifBinding specificity and mutational analysis of the phosphotyrosine binding domain of the brain-specific adaptor protein ShcC.Role of the Caenorhabditis elegans Shc adaptor protein in the c-Jun N-terminal kinase signaling pathwayLessons from polyoma middle T antigen on signaling and transformation: A DNA tumor virus contribution to the war on cancer.The ShcD signaling adaptor facilitates ligand-independent phosphorylation of the EGF receptor.The Roles of Insulin-Like Growth Factors in Mesenchymal Stem Cell NicheTeaching an old dogma new tricks: twenty years of Shc adaptor signalling.SchA-p85-FAK complex dictates isoform-specific activation of Akt2 and subsequent PCBP1-mediated post-transcriptional regulation of TGFβ-mediated epithelial to mesenchymal transition in human lung cancer cell line A549.Up-regulation of N-cadherin by Collagen I-activated Discoidin Domain Receptor 1 in Pancreatic Cancer Requires the Adaptor Molecule Shc1.Interactions of the NPXY microdomains of the low density lipoprotein receptor-related protein 1.Amyloid precursor protein modulates ERK-1 and -2 signaling.Engineering the recruitment of phosphotyrosine binding domain-containing adaptor proteins reveals distinct roles for RET receptor-mediated cell survival.
P2860
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P2860
Identification of residues that control specific binding of the Shc phosphotyrosine-binding domain to phosphotyrosine sites.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on February 1996
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Identification of residues tha ...... main to phosphotyrosine sites.
@en
Identification of residues tha ...... main to phosphotyrosine sites.
@nl
type
label
Identification of residues tha ...... main to phosphotyrosine sites.
@en
Identification of residues tha ...... main to phosphotyrosine sites.
@nl
prefLabel
Identification of residues tha ...... main to phosphotyrosine sites.
@en
Identification of residues tha ...... main to phosphotyrosine sites.
@nl
P2093
P2860
P356
P1476
Identification of residues tha ...... main to phosphotyrosine sites.
@en
P2093
P van der Geer
R Stephens
P2860
P304
P356
10.1073/PNAS.93.3.963
P407
P577
1996-02-01T00:00:00Z