Aggregation of granulocyte colony stimulating factor under physiological conditions: characterization and thermodynamic inhibition.
about
Conformational and aggregation properties of a PEGylated alanine-rich polypeptideNon-native aggregation of recombinant human granulocyte-colony stimulating factor under simulated process stress conditions.Conformational change in the C-terminal domain is responsible for the initiation of creatine kinase thermal aggregationFully Synthetic Granulocyte Colony-Stimulating Factor Enabled by Isonitrile-Mediated Coupling of Large, Side-Chain-Unprotected PeptidesAggregation of granulocyte-colony stimulating factor in vitro involves a conformationally altered monomeric state.Roles of conformational stability and colloidal stability in the aggregation of recombinant human granulocyte colony-stimulating factor.Effects of sucrose on conformational equilibria and fluctuations within the native-state ensemble of proteinsAggregation kinetics of recombinant human FVIII (rFVIII)Lipid binding region (2303-2332) is involved in aggregation of recombinant human FVIII (rFVIII)Effects of glycosylation on the stability of protein pharmaceuticals.Antibody nanoparticle dispersions formed with mixtures of crowding molecules retain activity and in vivo bioavailability.A comparison of biophysical characterization techniques in predicting monoclonal antibody stability.The use of self-interaction chromatography in stable formulation and crystallization of proteins.Analytical methods and formulation factors to enhance protein stability in solution.Immunogenicity of therapeutic proteins: influence of aggregation.Protein folding, misfolding, aggregation and their implications in human diseases: discovering therapeutic ways to amyloid-associated diseases.Substituted Polyesters by Thiol-Ene Modification: Rapid Diversification for Therapeutic Protein Stabilization.Physical instability of a therapeutic Fc fusion protein: domain contributions to conformational and colloidal stability.Nonspecific shielding of unfavorable electrostatic intramolecular interactions in the erythropoietin native-state increase conformational stability and limit non-native aggregation.Diffusion and sedimentation interaction parameters for measuring the second virial coefficient and their utility as predictors of protein aggregation.Milling solid proteins to enhance activity after melt-encapsulation.Modulation of protein aggregation by polyethylene glycol conjugation: GCSF as a case study.Silicone oil- and agitation-induced aggregation of a monoclonal antibody in aqueous solution.Second virial coefficient studies of cosolvent-induced protein self-interaction.Multistep aggregation pathway of human interleukin-1 receptor antagonist: kinetic, structural, and morphological characterization.Conformational transitions provoked by organic solvents in chicken egg ovalbumin: mimicking the local environment.Effect of protein and solution properties on the Donnan effect during the ultrafiltration of proteins.Factors affecting the physical stability (aggregation) of peptide therapeutics.Multi-step conformational transitions in heat-treated protein therapeutics can be monitored in real time with temperature-controlled electrospray ionization mass spectrometry.Optimization of protein solution by a novel experimental design method using thermodynamic properties.Fundamental analysis of recombinant human epidermal growth factor in solution with biophysical methods.Quality Comparison of Biosimilar and Copy Filgrastim Products with the Innovator Product
P2860
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P2860
Aggregation of granulocyte colony stimulating factor under physiological conditions: characterization and thermodynamic inhibition.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Aggregation of granulocyte col ...... and thermodynamic inhibition.
@en
type
label
Aggregation of granulocyte col ...... and thermodynamic inhibition.
@en
prefLabel
Aggregation of granulocyte col ...... and thermodynamic inhibition.
@en
P2093
P356
P1433
P1476
Aggregation of granulocyte col ...... and thermodynamic inhibition.
@en
P2093
Byeong S Chang
Daxian Shan
John F Carpenter
Jonathan N Webb
Mark C Manning
Merrill Goldenberg
Sampathkumar Krishnan
P304
P356
10.1021/BI012006M
P407
P577
2002-05-01T00:00:00Z