Silicone oil- and agitation-induced aggregation of a monoclonal antibody in aqueous solution. - Wikidata - awgldk - TriplyDB

Silicone oil- and agitation-induced aggregation of a monoclonal antibody in aqueous solution.

Silicone oil- and agitation-induced aggregation of a monoclonal antibody in aqueous solution.

http://www.wikidata.org/entity/Q42108007

about

Protein comparability assessments and potential applicability of high throughput biophysical methods and data visualization tools to compare physical stability profiles In Vivo Analysis of the Potency of Silicone Oil Microdroplets as Immunological Adjuvants in Protein Formulations Silicone Oil Microdroplets Can Induce Antibody Responses Against Recombinant Murine Growth Hormone in Mice.Aggregation mechanism of an IgG2 and two IgG1 monoclonal antibodies at low pH: from oligomers to larger aggregates.Silicone oil microdroplets and protein aggregates in repackaged bevacizumab and ranibizumab: effects of long-term storage and product mishandling Remediating agitation-induced antibody aggregation by eradicating exposed hydrophobic motifs.Surfactant Effects on Particle Generation in Antibody Formulations in Pre-filled Syringes Understanding the immunogenicity and antigenicity of nanomaterials: Past, present and future.Probing residue-specific interactions in the stabilization of proteins using high-resolution NMR: a study of disulfide bond compensation.Practical fundamentals of glass, rubber, and plastic sterile packaging systems.Strategies for the assessment of protein aggregates in pharmaceutical biotech product development Effects of shear on proteins in solution.Aggregates in monoclonal antibody manufacturing processes.Protein particulate detection issues in biotherapeutics development--current status.Biopharmaceutical formulations for pre-filled delivery devices.Immunogenicity of therapeutic proteins: influence of aggregation.Formation, clearance, deposition, pathogenicity, and identification of biopharmaceutical-related immune complexes: review and case studies.Influence of particle shedding from silicone tubing on antibody stability.Interfacial dilatational deformation accelerates particle formation in monoclonal antibody solutions.Functional evaluation and characterization of a newly developed silicone oil-free prefillable syringe system.A Flow-Cytometry-Based Approach to Facilitate Quantification, Size Estimation and Characterization of Sub-visible Particles in Protein Solutions.Fluorescent molecular rotors as dyes to characterize polysorbate-containing IgG formulations.The use of native cation-exchange chromatography to study aggregation and phase separation of monoclonal antibodies.Development of biotechnology products in pre-filled syringes: technical considerations and approaches.The stability of insulin solutions in syringes is improved by ensuring lower molecular weight silicone lubricants are absent.Flow cytometry: a promising technique for the study of silicone oil-induced particulate formation in protein formulations Effects of syringe material and silicone oil lubrication on the stability of pharmaceutical proteins.Protein-silicone oil interactions: comparative effect of nonionic surfactants on the interfacial behavior of a fusion protein.Protein-protein interactions controlling interfacial aggregation of rhIL-1ra are not described by simple colloid models.Effect of Polysorbate 20 and Polysorbate 80 on the Higher-Order Structure of a Monoclonal Antibody and Its Fab and Fc Fragments Probed Using 2D Nuclear Magnetic Resonance Spectroscopy.Protein Adsorption and Layer Formation at the Stainless Steel-Solution Interface Mediates Shear-Induced Particle Formation for an IgG1 Monoclonal Antibody.High-throughput screening of excipients intended to prevent antigen aggregation at air-liquid interface.Conformational Analysis of Proteins in Highly Concentrated Solutions by Dialysis-Coupled Hydrogen/Deuterium Exchange Mass Spectrometry.

P2860

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P2860

Silicone oil- and agitation-induced aggregation of a monoclonal antibody in aqueous solution.

http://www.wikidata.org/entity/Q42108007

description

2009 nî lūn-bûn

@nan

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

2009年论文

@zh

2009年论文

@zh-cn

name

Silicone oil- and agitation-in ...... antibody in aqueous solution.

@en

Silicone oil- and agitation-in ...... antibody in aqueous solution.

@nl

type

label

Silicone oil- and agitation-in ...... antibody in aqueous solution.

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Silicone oil- and agitation-in ...... antibody in aqueous solution.

@nl

prefLabel

Silicone oil- and agitation-in ...... antibody in aqueous solution.

@en

Silicone oil- and agitation-in ...... antibody in aqueous solution.

@nl

P1433

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P1433

Journal of Pharmaceutical Sciences

P1476

Silicone oil- and agitation-in ...... antibody in aqueous solution.

@en

P2093

David N Brems

http://www.w3.org/2001/XMLSchema#string

John F Carpenter

http://www.w3.org/2001/XMLSchema#string

Margaret Speed Ricci

http://www.w3.org/2001/XMLSchema#string

Renuka Thirumangalathu

http://www.w3.org/2001/XMLSchema#string

Sampathkumar Krishnan

http://www.w3.org/2001/XMLSchema#string

P2860

Effects of Tween 20 and Tween 80 on the stability of Albutropin during agitation

Antibodies as therapeutic agents: vive la renaissance!

Physical stability of proteins in aqueous solution: mechanism and driving forces in nonnative protein aggregation.

Roles of conformational stability and colloidal stability in the aggregation of recombinant human granulocyte colony-stimulating factor.

Effects of protein aggregates: an immunologic perspective

Preferential exclusion of sucrose from recombinant interleukin-1 receptor antagonist: role in restricted conformational mobility and compaction of native state.

Kinetics of insulin aggregation in aqueous solutions upon agitation in the presence of hydrophobic surfaces.

Aggregation of granulocyte colony stimulating factor under physiological conditions: characterization and thermodynamic inhibition.

The stabilization of proteins by sucrose.

Infrared methods for study of hemoglobin reactions and structures.

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3167-3181

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scholarly article

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10.1002/JPS.21719

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9

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98

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Theodore W Randolph

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2009-09-01T00:00:00Z

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24272306

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19360857

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2751612

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