Transcriptional repression by p53 through direct binding to a novel DNA element.
about
The transcription factor p53: not a repressor, solely an activatorHOXA5 regulates hMLH1 expression in breast cancer cellsSAK, a new polo-like kinase, is transcriptionally repressed by p53 and induces apoptosis upon RNAi silencingBipartite recognition of DNA by TCF/Pangolin is remarkably flexible and contributes to transcriptional responsiveness and tissue specificity of wingless signalingReciprocal repression between P53 and TCTPWnt-mediated repression via bipartite DNA recognition by TCF in the Drosophila hematopoietic systemEstrogen receptor acting in cis enhances WT and mutant p53 transactivation at canonical and noncanonical p53 target sequences.More targets, more pathways and more clues for mutant p53.Visualization and enrichment of live putative cancer stem cell populations following p53 inactivation or Bax deletion using non-toxic fluorescent dyes.The p53 tumor suppressor protein represses human snRNA gene transcription by RNA polymerases II and III independently of sequence-specific DNA bindingDeltaNp73alpha regulates MDR1 expression by inhibiting p53 function.Identification of two novel functional p53 responsive elements in the herpes simplex virus-1 genome.Mdr1 gene expression and mutations in Ras proto-oncogenes in acute myeloid leukemia.Molecular pathways: regulation and therapeutic implications of multidrug resistancep53 Dimers associate with a head-to-tail response element to repress cyclin B transcriptionCancer chemoresistance: the relationship between p53 and multidrug transporters.TSPAN12 is a critical factor for cancer-fibroblast cell contact-mediated cancer invasionGrowth-inhibitory and tumor- suppressive functions of p53 depend on its repression of CD44 expressionDistinct regulatory mechanisms and functions for p53-activated and p53-repressed DNA damage response genes in embryonic stem cellsTranscriptional repression of cancer stem cell marker CD133 by tumor suppressor p53.Etoposide enhances antitumor efficacy of MDR1-driven oncolytic adenovirus through autoupregulation of the MDR1 promoter activity.Mechanisms of doxorubicin resistance in hepatocellular carcinomaChanging the p53 master regulatory network: ELEMENTary, my dear Mr Watson.Versatile functions of p53 protein in multicellular organismsRegulation of multidrug resistance 1 expression by CDX2 in ovarian mucinous adenocarcinoma.DNA damage induced p53 downregulates Cdc20 by direct binding to its promoter causing chromatin remodelingRescue of key features of the p63-null epithelial phenotype by inactivation of Ink4a and Arf.Survivin regulation by HER2 through NF-κB and c-myc in irradiated breast cancer cells.Transcriptional regulation by p53.One function--multiple mechanisms: the manifold activities of p53 as a transcriptional repressor.Global transcriptional program of p53 target genes during the process of apoptosis and cell cycle progression.Spatial repression of PCNA by p53 during kidney development.Census and evaluation of p53 target genes.Structurally diverse MDM2-p53 antagonists act as modulators of MDR-1 function in neuroblastoma.p53 in human embryonal carcinoma: identification of a transferable, transcriptional repression domain in the N-terminal region of p53.The temporal relationship between ABCB1 promoter hypomethylation, ABCB1 expression and acquisition of drug resistance.Multiplex enhancer-reporter assays uncover unsophisticated TP53 enhancer logic.Transcriptional repression by p53 promotes a Bcl-2-insensitive and mitochondria-independent pathway of apoptosisGene expression of cyclin-dependent kinase subunit Cks2 is repressed by the tumor suppressor p53 but not by the related proteins p63 or p73.Identification of cell cycle regulatory genes as principal targets of p53-mediated transcriptional repression.
P2860
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P2860
Transcriptional repression by p53 through direct binding to a novel DNA element.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Transcriptional repression by p53 through direct binding to a novel DNA element.
@en
type
label
Transcriptional repression by p53 through direct binding to a novel DNA element.
@en
prefLabel
Transcriptional repression by p53 through direct binding to a novel DNA element.
@en
P2093
P2860
P356
P1476
Transcriptional repression by p53 through direct binding to a novel DNA element.
@en
P2093
P2860
P304
27716-27720
P356
10.1074/JBC.C100121200
P407
P577
2001-05-11T00:00:00Z