Global transcriptional program of p53 target genes during the process of apoptosis and cell cycle progression. - Wikidata - awgldk - TriplyDB

Global transcriptional program of p53 target genes during the process of apoptosis and cell cycle progression.

Global transcriptional program of p53 target genes during the process of apoptosis and cell cycle progression.

http://www.wikidata.org/entity/Q38353894

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MAPPER: a search engine for the computational identification of putative transcription factor binding sites in multiple genomes The transcription factor p53: not a repressor, solely an activator Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway p53 downregulates its activating vaccinia-related kinase 1, forming a new autoregulatory loop Threshold effects of nitric oxide-induced toxicity and cellular responses in wild-type and p53-null human lymphoblastoid cells Nutlin-3a activates p53 to both down-regulate inhibitor of growth 2 and up-regulate mir-34a, mir-34b, and mir-34c expression, and induce senescence Modulation of p53 activity by IkappaBalpha: evidence suggesting a common phylogeny between NF-kappaB and p53 transcription factors.Potential roles for prions and protein-only inheritance in cancer Another fork in the road--life or death decisions by the tumour suppressor p53 Putting the pieces together: How is the mitochondrial pathway of apoptosis regulated in cancer and chemotherapy?The p53-p21-DREAM-CDE/CHR pathway regulates G2/M cell cycle genes DNA damage-induced expression of p53 suppresses mitotic checkpoint kinase hMps1: the lack of this suppression in p53MUT cells contributes to apoptosis TIP30 regulates apoptosis-related genes in its apoptotic signal transduction pathway Histone demethylase Jumonji D3 (JMJD3) as a tumor suppressor by regulating p53 protein nuclear stabilization Oscillations of the p53-Akt network: implications on cell survival and death SLC25A1, or CIC, is a novel transcriptional target of mutant p53 and a negative tumor prognostic marker Association of intron and exon polymorphisms of p53 gene in Iranian patients with gastritis.Transcriptional networks and cellular senescence in human mammary fibroblasts.p53-dependent gene repression through p21 is mediated by recruitment of E2F4 repression complexes.Pro-proliferative FoxM1 is a target of p53-mediated repression.p53 directly suppresses BNIP3 expression to protect against hypoxia-induced cell death.A resource for discovering specific and universal biomarkers for distributed stem cells Tumor suppressor protein p53 recruits human Sin3B/HDAC1 complex for down-regulation of its target promoters in response to genotoxic stress.Deciphering causal and statistical relations of molecular aberrations and gene expressions in NCI-60 cell lines.Functional Genomics and a New Era in Radiation Biology and Oncology.Integrative genomics revealed RAI3 is a cell growth-promoting gene and a novel P53 transcriptional target.The p53 tumor suppressor network is a key responder to microenvironmental components of chronic inflammatory stress.Impact of Alu repeats on the evolution of human p53 binding sites.Essential dosage-dependent functions of the transcription factor yin yang 1 in late embryonic development and cell cycle progression.Analysing microarray data in drug discovery using systems biology.Acetylation of mouse p53 at lysine 317 negatively regulates p53 apoptotic activities after DNA damage Phenotype specific analyses reveal distinct regulatory mechanism for chronically activated p53 Qualitative network modeling of the Myc-p53 control system of cell proliferation and differentiation p53 targets identified by protein expression profiling Identification of primary transcriptional regulation of cell cycle-regulated genes upon DNA damage Protein lysine acetylation in normal and leukaemic haematopoiesis: HDACs as possible therapeutic targets in adult AML.Control of cell migration: a tumour suppressor function for p53?MDM4/HIPK2/p53 cytoplasmic assembly uncovers coordinated repression of molecules with anti-apoptotic activity during early DNA damage response Methylation of RASSF1A gene promoter is regulated by p53 and DAXX.A threshold mechanism mediates p53 cell fate decision between growth arrest and apoptosis.

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P2860

Global transcriptional program of p53 target genes during the process of apoptosis and cell cycle progression.

http://www.wikidata.org/entity/Q38353894

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2003 nî lūn-bûn

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2003年の論文

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2003年学术文章

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2003年学术文章

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2003年学术文章

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Global transcriptional program ...... is and cell cycle progression.

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Global transcriptional program ...... is and cell cycle progression.

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Global transcriptional program ...... is and cell cycle progression.

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Asra Mirza

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Beth Hutchins

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Ferdous Gheyas

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Jonathan R Greene

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Luquan Wang

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Paul Kirschmeier

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Qun Wu

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Suxing Liu

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Terri McClanahan

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Tish Hockenberry

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P2860

Wild-type p53 binds to the TATA-binding protein and represses transcription

Human TAFII31 protein is a transcriptional coactivator of the p53 protein

Cluster analysis and display of genome-wide expression patterns

Exploring the metabolic and genetic control of gene expression on a genomic scale

p53 suppresses the activation of the Bcl-2 promoter by the Brn-3a POU family transcription factor

Transcriptional activation of the human proliferating-cell nuclear antigen promoter by p53.

Identification and classification of p53-regulated genes.

Differential gene expression in p53-mediated apoptosis-resistant vs. apoptosis-sensitive tumor cell lines.

Analyses of p53 target genes in the human genome by bioinformatic and microarray approaches.

Transcriptional repression by p53 through direct binding to a novel DNA element.

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10.1038/SJ.ONC.1206477

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1016108809

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apoptotic process