Interactions of TLC1 (which encodes the RNA subunit of telomerase), TEL1, and MEC1 in regulating telomere length in the yeast Saccharomyces cerevisiae
about
DNA end resection: many nucleases make light workSaccharomyces cerevisiae Dap1p, a novel DNA damage response protein related to the mammalian membrane-associated progesterone receptorProgressive rearrangement of telomeric sequences added to both the ITR ends of the yeast linear pGKL plasmidLimited TTP supply affects telomere length regulation in a telomerase-independent fashionA network of multi-tasking proteins at the DNA replication fork preserves genome stabilitytrt-1 is the Caenorhabditis elegans catalytic subunit of telomerase.Epigenetic telomere protection by Drosophila DNA damage response pathwaysAt short telomeres Tel1 directs early replication and phosphorylates Rif1.The Saccharomyces cerevisiae suppressor of choline sensitivity (SCS2) gene is a multicopy Suppressor of mec1 telomeric silencing defectsA SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organizationProtein kinase activity of Tel1p and Mec1p, two Saccharomyces cerevisiae proteins related to the human ATM protein kinase.TLC1 RNA nucleo-cytoplasmic trafficking links telomerase biogenesis to its recruitment to telomeresLongevity regulation in Saccharomyces cerevisiae: linking metabolism, genome stability, and heterochromatinContribution of Trf4/5 and the nuclear exosome to genome stability through regulation of histone mRNA levels in Saccharomyces cerevisiae.Involvement of the checkpoint protein Mec1p in silencing of gene expression at telomeres in Saccharomyces cerevisiaeMEC3, MEC1, and DDC2 are essential components of a telomere checkpoint pathway required for cell cycle arrest during senescence in Saccharomyces cerevisiae.Cdk1-dependent phosphorylation of Cdc13 coordinates telomere elongation during cell-cycle progression.Telomerase and Tel1p preferentially associate with short telomeres in S. cerevisiae.Role for the silencing protein Dot1 in meiotic checkpoint control.Tel1 kinase and subtelomere-bound Tbf1 mediate preferential elongation of short telomeres by telomerase in yeast.Control of the yeast telomeric senescence survival pathways of recombination by the Mec1 and Mec3 DNA damage sensors and RPA.Def1p is involved in telomere maintenance in budding yeast.Pol12, the B subunit of DNA polymerase alpha, functions in both telomere capping and length regulation.Length-dependent processing of telomeres in the absence of telomerase.ATM Kinase Is Required for Telomere Elongation in Mouse and Human CellsMRE11-RAD50-NBS1 and ATM function as co-mediators of TRF1 in telomere length controlThe ribonucleotide reductase inhibitor Sml1 is a new target of the Mec1/Rad53 kinase cascade during growth and in response to DNA damage.Hyperactivation of the yeast DNA damage checkpoint by TEL1 and DDC2 overexpression.Mutational landscape of yeast mutator strainsRole of RAD52 epistasis group genes in homologous recombination and double-strand break repairYeast telomerase is specialized for C/A-rich RNA templates.The asymmetry of telomere replication contributes to replicative senescence heterogeneity.DNA repair pathway selection caused by defects in TEL1, SAE2, and de novo telomere addition generates specific chromosomal rearrangement signatures.Role of the C terminus of Mec1 checkpoint kinase in its localization to sites of DNA damage.Fission yeast Tel1(ATM) and Rad3(ATR) promote telomere protection and telomerase recruitment.The MRT-1 nuclease is required for DNA crosslink repair and telomerase activity in vivo in Caenorhabditis elegansA kinase-independent role for the Rad3(ATR)-Rad26(ATRIP) complex in recruitment of Tel1(ATM) to telomeres in fission yeastRoles of the checkpoint sensor clamp Rad9-Rad1-Hus1 (911)-complex and the clamp loaders Rad17-RFC and Ctf18-RFC in Schizosaccharomyces pombe telomere maintenanceTelomerase-dependent repeat divergence at the 3' ends of yeast telomeres.A two-step model for senescence triggered by a single critically short telomere.
P2860
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P2860
Interactions of TLC1 (which encodes the RNA subunit of telomerase), TEL1, and MEC1 in regulating telomere length in the yeast Saccharomyces cerevisiae
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
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1999年學術文章
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name
Interactions of TLC1 (which en ...... yeast Saccharomyces cerevisiae
@en
type
label
Interactions of TLC1 (which en ...... yeast Saccharomyces cerevisiae
@en
prefLabel
Interactions of TLC1 (which en ...... yeast Saccharomyces cerevisiae
@en
P2093
P2860
P356
P1476
Interactions of TLC1 (which en ...... yeast Saccharomyces cerevisiae
@en
P2093
J C Mallory
K B Ritchie
P2860
P304
P356
10.1128/MCB.19.9.6065
P407
P577
1999-09-01T00:00:00Z