Oncogenic Ras diverts a host TNF tumor suppressor activity into tumor promoter.
about
Drosophila at the intersection of infection, inflammation, and cancerDamage signals in the insect immune responseCell competition: how to eliminate your neighboursTransgenic expression of the Helicobacter pylori virulence factor CagA promotes apoptosis or tumorigenesis through JNK activation in DrosophilaSterile inflammation in DrosophilaInflammation meets cancer, with NF-κB as the matchmakerCo-inhibition of NF-κB and JNK is synergistic in TNF-expressing human AML.Macrophages in multiple myeloma: emerging concepts and therapeutic implications.Intercellular cooperation and competition in brain cancers: lessons from Drosophila and human studies.Oncogenic Ras stimulates Eiger/TNF exocytosis to promote growth.Identification of novel Ras-cooperating oncogenes in Drosophila melanogaster: a RhoGEF/Rho-family/JNK pathway is a central driver of tumorigenesis.The orthologous Tbx transcription factors Omb and TBX2 induce epithelial cell migration and extrusion in vivo without involvement of matrix metalloproteinasesLoss of the polarity protein PAR3 activates STAT3 signaling via an atypical protein kinase C (aPKC)/NF-κB/interleukin-6 (IL-6) axis in mouse mammary cells.Malignant Drosophila tumors interrupt insulin signaling to induce cachexia-like wasting.Modeling tumor invasion and metastasis in DrosophilaConserved metabolic energy production pathways govern Eiger/TNF-induced nonapoptotic cell death.Tumor suppression by cell competition through regulation of the Hippo pathway.BTB-Zinc Finger Oncogenes Are Required for Ras and Notch-Driven Tumorigenesis in Drosophila.Crosstalk between Tumor Cells and Macrophages in Stroma Renders Tumor Cells as the Primary Source of MCP-1/CCL2 in Lewis Lung Carcinoma.Loss of Cell Adhesion Increases Tumorigenic Potential of Polarity Deficient Scribble Mutant CellsDisruption of the Cdc42/Par6/aPKC or Dlg/Scrib/Lgl Polarity Complex Promotes Epithelial Proliferation via Overlapping Mechanisms.A protein complex of SCRIB, NOS1AP and VANGL1 regulates cell polarity and migration, and is associated with breast cancer progression.Accumulation of differentiating intestinal stem cell progenies drives tumorigenesisExtracellular Reactive Oxygen Species Drive Apoptosis-Induced Proliferation via Drosophila Macrophages.An in vivo large-scale chemical screening platform using Drosophila for anti-cancer drug discovery.Mechanisms of cell competition: themes and variations.In Drosophila, RhoGEF2 cooperates with activated Ras in tumorigenesis through a pathway involving Rho1-Rok-Myosin-II and JNK signallingCell polarity in morphogenesis and metastasisEnhancement of hyperthermia-induced apoptosis by 5Z-7-oxozeaenol, a TAK1 inhibitor, in A549 cellsMacrophages and cellular immunity in Drosophila melanogasterDrosophila as a model to study the role of blood cells in inflammation, innate immunity and cancer.Variation of NimC1 expression in Drosophila stocks and transgenic strains.Inhibition of tumor necrosis factor alpha reduces the outgrowth of hepatic micrometastasis of colorectal tumors in a mouse model of liver ischemia-reperfusion injury.Src42A modulates tumor invasion and cell death via Ben/dUev1a-mediated JNK activation in Drosophila.Bendless modulates JNK-mediated cell death and migration in Drosophila.Reduced LIMK2 expression in colorectal cancer reflects its role in limiting stem cell proliferation.Preliminary indications of the effect of a brief yoga intervention on markers of inflammation and DNA methylation in chronically stressed women.Macrophage Functions in Tissue Patterning and Disease: New Insights from the Fly.Radiation-enhanced lung cancer progression in a transgenic mouse model of lung cancer is predictive of outcomes in human lung and breast cancerDissecting social cell biology and tumors using Drosophila genetics.
P2860
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P2860
Oncogenic Ras diverts a host TNF tumor suppressor activity into tumor promoter.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Oncogenic Ras diverts a host TNF tumor suppressor activity into tumor promoter.
@en
type
label
Oncogenic Ras diverts a host TNF tumor suppressor activity into tumor promoter.
@en
prefLabel
Oncogenic Ras diverts a host TNF tumor suppressor activity into tumor promoter.
@en
P2093
P2860
P50
P1433
P1476
Oncogenic Ras diverts a host TNF tumor suppressor activity into tumor promoter.
@en
P2093
Juan P Macagno
Karen E Strathdee
Ross L Cagan
P2860
P304
P356
10.1016/J.DEVCEL.2010.05.014
P407
P577
2010-06-01T00:00:00Z