Properties of the tetrodotoxin binding component in plasma membranes isolated from Electrophorus electricus.
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An unexpected role for brain-type sodium channels in coupling of cell surface depolarization to contraction in the heart.Competitive binding interaction between Zn2+ and saxitoxin in cardiac Na+ channels. Evidence for a sulfhydryl group in the Zn2+/saxitoxin binding site.Interaction of nonylguanidine with the sodium channel.Influence of negative surface charge on toxin binding to canine heart Na channels in planar bilayers.Membrane potential dependent binding of scorpion toxin to action potential Na+ ionophore.Functional expression of "cardiac-type" Nav1.5 sodium channel in canine intracardiac ganglia.Use-dependent block of the voltage-gated Na(+) channel by tetrodotoxin and saxitoxin: effect of pore mutations that change ionic selectivity.Comparison of ionic selectivity of batrachotoxin-activated channels with different tetrodotoxin dissociation constants.Batrachotoxin-modified sodium channels in planar lipid bilayers. Characterization of saxitoxin- and tetrodotoxin-induced channel closures.Divalent cation competition with [3H]saxitoxin binding to tetrodotoxin-resistant and -sensitive sodium channels. A two-site structural model of ion/toxin interaction.Modification of cardiac sodium channels by carboxyl reagents. Trimethyloxonium and water-soluble carbodiimide.Trimethyloxonium modification of single batrachotoxin-activated sodium channels in planar bilayers. Changes in unit conductance and in block by saxitoxin and calciumVoltage-dependent blockade of muscle Na+ channels by guanidinium toxinsPurification of the tetrodotoxin-binding component associated with the voltage-sensitive sodium channel from Electrophorus electricus electroplax membranes.Identification of two sodium channel subtypes in chick heart and brain.The tetrodotoxin binding site is within the outer vestibule of the sodium channel.Blocking mechanisms of batrachotoxin-activated Na channels in artificial bilayers.Analysis of saxitoxin binding in isolated rat synaptosomes using a rapid filtration assay.Saxitoxin binding to the mammalian sodium channel. Competition by monovalent and divalent cations.Ionic channels in excitable membranes. Current problems and biophysical approaches.Isolation of membrane fractions with sodium channels sensitive to veratridine and tetrodotoxin from the electric organ of the eel Electrophorus electricus.On the mechanism by which saxitoxin binds to and blocks sodium channels.Block of sodium channels in planar lipid bilayers by guanidium toxins and calcium. Are the mechanisms of voltage dependence the same?A mutant of TTX-resistant cardiac sodium channels with TTX-sensitive properties.Mapping the site of block by tetrodotoxin and saxitoxin of sodium channel II.A single point mutation confers tetrodotoxin and saxitoxin insensitivity on the sodium channel II.Surface charges near the guanidinium neurotoxin binding site.
P2860
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P2860
Properties of the tetrodotoxin binding component in plasma membranes isolated from Electrophorus electricus.
description
1976 nî lūn-bûn
@nan
1976年の論文
@ja
1976年論文
@yue
1976年論文
@zh-hant
1976年論文
@zh-hk
1976年論文
@zh-mo
1976年論文
@zh-tw
1976年论文
@wuu
1976年论文
@zh
1976年论文
@zh-cn
name
Properties of the tetrodotoxin ...... from Electrophorus electricus.
@en
Properties of the tetrodotoxin ...... from Electrophorus electricus.
@nl
type
label
Properties of the tetrodotoxin ...... from Electrophorus electricus.
@en
Properties of the tetrodotoxin ...... from Electrophorus electricus.
@nl
prefLabel
Properties of the tetrodotoxin ...... from Electrophorus electricus.
@en
Properties of the tetrodotoxin ...... from Electrophorus electricus.
@nl
P356
P1433
P1476
Properties of the tetrodotoxin ...... from Electrophorus electricus.
@en
P2093
P304
P356
10.1021/BI00650A002
P407
P577
1976-03-01T00:00:00Z